Gel agent for treating glaucoma and its preparing process
A gel, glaucoma technology, applied in the field of medicine, can solve the problem of high price, and achieve the effects of reducing the possibility of absorption, reducing side effects, and being convenient to use
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Embodiment 1
[0017] Raw material parts by weight
[0018] Timolol maleate 0.6830
[0019] Hydroxypropyl Methyl Cellulose 1.5
[0020] Ethylparaben 0.03
[0021] Edetate disodium (EDTA-2Na) 0.03
[0022] Sodium sulfite 0.2
[0023] Glycerin 2
[0024] Add distilled water to 100.
[0025] Preparation:
[0026] A Dissolve hydroxypropyl methylcellulose in water first, which is called a solution.
[0027] B Dissolve the prescribed amount of ethylparaben with hot water, the temperature of which is 80 or 85 or 88 or 90 or 92 or 95°C, called b solution.
[0028] C Add solution b, timolol maleate, disodium edetate (EDTA-2Na), sodium sulfite, and glycerin to solution a according to the above ratio, and add 100 parts of distilled water. Timolol maleate gel can be made. The drug content in the gel is 0.5%.
Embodiment 2
[0030] Raw material parts by weight
[0031] Timolol maleate 0.3415
[0032] Hydroxypropyl Methyl Cellulose 1.0
[0033] Ethylparaben 0.03
[0034] Edetate disodium (EDTA-2Na) 0.03
[0035] Sodium bisulfite 0.2
[0036] Glycerin 2
[0037] Add distilled water to 100.
[0038] The preparation steps are the same as in Example 1. The drug content in the gel is 0.25%.
Embodiment 3
[0040] Raw material parts by weight
[0041] Timolol maleate 0.6830
[0042] Methylcellulose 1.0
[0043] Ethylparaben 0.03
[0044] Edetate disodium (EDTA-2Na) 0.03
[0045] Sodium bisulfite 0.2
[0046] Glycerin 2
[0047] Add distilled water to 100.
[0048] The preparation steps are the same as in Example 1. The drug content in the gel is 0.5%
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