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Injection for curing diarrhea of pig and preparation thereof

A technology for injection and swine dysentery, which is applied in the field of injection for treating swine dysentery and its preparation, can solve the problems of poor drug sensitivity in the treatment effect, increase the dosage of drugs, prolong the treatment time, etc., and achieve the goal of reducing the drug resistance of bacteria Odds, reduction in frequency and dose of medication, effects of weight gain

Inactive Publication Date: 2009-10-14
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The drugs currently used in the treatment of swine dysentery, such as acemethaquine and lincomycin hydrochloride, have generally increased drug resistance in pigs due to long-term drug use in recent years. During the long-term treatment and preventive drug use, the use of drugs cannot reach Satisfactory treatment effect or sensitivity to drugs is getting worse, and sometimes other secondary infections occur during treatment due to prolonged treatment time, causing other diseases and high mortality
At the same time, in order to treat diseases, farmers increase the dosage of drugs or prolong the use time, and the drug residues exceed the standard.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] (1) Take 30 L of water for injection, add 1.5 kg of sodium salicylate, stir to dissolve, then add 0.5 kg of acetylmethaquine, and stir until completely dissolved.

[0019] (2) Take 20 L of water for injection, add 0.01 kg of EDTA-2Na, 0.2 kg of sodium bisulfite, 0.2 kg of atropine sulfate, and 10 kg of lincomycin hydrochloride, and stir until completely dissolved.

[0020] (3) Combine the solution prepared in step 1 and step 2, then add water for injection to 100L, stir evenly, keep for 15-20min, and make the injection for treating swine dysentery of the present invention after the liquid is clear.

Embodiment 2

[0022] (1) Take 30 L of water for injection, add 30 kg of sodium salicylate, stir to dissolve, then add 10 kg of acemethaquine, and stir until completely dissolved.

[0023] (2) Take 20 L of water for injection, add 0.01 kg of EDTA-2Na, 0.2 kg of sodium bisulfite, 0.2 kg of atropine sulfate, and 1 kg of lincomycin hydrochloride, and stir until completely dissolved.

[0024] (3) Combine the prepared solution of step 1 and step 2, then add water for injection to 100L, stir evenly, keep for 15-20min, and make the injection for treating swine dysentery of the present invention after the liquid is clear.

Embodiment 3

[0026] (1) Take 30 L of water for injection, add 6 kg of sodium salicylate, stir to dissolve, then add 2 kg of acemethaquine, and stir until completely dissolved.

[0027] (2) Take 20 L of water for injection, add 0.01 kg of EDTA-2Na, 0.2 kg of sodium bisulfite, 0.2 kg of atropine sulfate, and 7 kg of lincomycin hydrochloride, and stir until completely dissolved.

[0028] (3) Combine the prepared solution of step 1 and step 2, then add water for injection to 100L, stir evenly, keep for 15-20min, and make the injection for treating swine dysentery of the present invention after the liquid is clear.

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PUM

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Abstract

The invention discloses an injection for treating swine dysentery and a preparation method thereof, aiming to provide an injection for treating swine dysentery that has quick effect, reduces the frequency and dose of medication, and reduces the occurrence of excessive drug residues for treating swine dysentery. The injection and its process are simple and easy to realize preparation method. Each 100L injection includes: acetylmequine 0.5-10kg, lincomycin hydrochloride 1-10kg, sodium bisulfite 0.2kg, sodium salicylate 1.5-30kg, EDTA-2Na 0.01kg, atropine sulfate 0.2kg, the balance For injection water. The present invention is a compound preparation using antibacterial drugs and antibiotics in combination. Acetamequin and lincomycin hydrochloride are used in combination, and adopt double effects to double inhibit Treponema hyodysenteriae, reduce the probability of bacterial drug resistance, and increase the incidence of swine dysentery. The sensitivity of Treponema, together with the inhibition of the secretion of intestinal digestive glands by atropine sulfate, reduces the amount of intestinal water during the disease of pigs, and the treatment of swine dysentery is effective.

Description

technical field [0001] The invention relates to an injection for treating swine dysentery and a preparation method thereof. Background technique [0002] Swine dysentery is a common intestinal disease in pigs. It is characterized by catarrhal hemorrhagic inflammation of the large intestine mucosa and then develops into fibrinous necrotizing enteritis. It is clinically manifested as mucus or mucohemorrhagic diarrhea. The pathogen is swine dysentery Treponema, diseased pigs and pigs with bacteria are the source of infection of this disease. The carrier rate is high, and the carrier time can be as long as more than 70 days. In addition to causing death of pigs, it can also reduce feed utilization and hinder growth and development. [0003] The drugs currently used in the treatment of swine dysentery, such as acemethaquine and lincomycin hydrochloride, etc., due to long-term drug use in recent years, have generally increased the drug resistance of pigs. Satisfactory therapeutic...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/498A61K9/08A61K31/7056A61P1/12A61P31/00
Inventor 徐克福
Owner TIANJIN SHENGJI GRP CO LTD
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