An ultrasonic equipment for treatment of osteoarthritis

A technology of ultrasound and arthritis, which is applied in the direction of ultrasound therapy and treatment, and can solve problems such as poor effect

Inactive Publication Date: 2007-11-07
DUPLOGEN INC +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0008] However, the above-mentioned arthritis treatment instruments require close adhesion to very curved joints or require the use of separate elements that can enhance the effect of ultrasound to achieve accompanying effects, and they have a disadvantage that they are used as instruments for fundamentally treating joints. The effect is relatively poor

Method used

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  • An ultrasonic equipment for treatment of osteoarthritis
  • An ultrasonic equipment for treatment of osteoarthritis
  • An ultrasonic equipment for treatment of osteoarthritis

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Experimental program
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Effect test

Embodiment 1

[0046] In order to examine the effect of the ultrasonic apparatus for treating arthritis of the present invention, the next test will be carried out using experimental animals in which arthritis has been induced. In the test, in addition to ultrasound radiation, hyaluronic acid, which is widely used in the treatment of osteoarthritis, was also injected into test animals. Hyaluronic acid is similar to the bone fluid of the joint, so when it is injected into the joint, it can effectively treat osteoarthritis because it protects the articular cartilage by covering the lubricant, and it is absorbed into the periosteal membrane or cartilage tissue so that Synthesis of hyaluronic acid can be activated by bone fluid cells. When osteoarthritis develops, damage to the joints becomes severe because the production of hyaluronic acid, which acts as joint lubricant, decreases so that the joints cannot absorb or disperse external influences. It is known that hyaluronic acid, which is used ...

Embodiment 2

[0054] In order to determine the optimum ultrasonic intensity, various experiments were performed by changing the ultrasonic intensity while the frequency was fixed at 1 MHz. To examine the in vitro effect of ultrasound on the proliferation and metabolism of collagen cells, the following conventional methods were used: an explant culture method of culturing cartilage tissue directly in human joints; a monolayer culture method of culturing chondrocytes separated from chondrocytes ; and alginate culture. The single-molecule culture method is a culture method that can effectively observe the proliferation of chondrocytes, the explant culture method is a culture method that is easy to observe the synthesis of cartilage matrix in chondrocytes, and the alginate culture method is a culture method in which the chondrocyte matrix The culture method was experimentally synthesized and effective in maintaining the chondrocyte phenotype.

[0055] The effect of ultrasound on the reproducti...

Embodiment 3

[0059] Embodiment 3: clinical test

[0060] To evaluate the efficacy of ultrasound in the treatment of knee osteoarthritis, a clinical trial was conducted in 46 patients (40 women and 6 men). Selected trial patients were patients with knee pain who were diagnosed with radiographically grade 1-3 osteoarthritis of the knee joint by radiographic test results, and patients with inflammatory arthritis, such as rheumatoid arthritis, were excluded from the selection outside.

[0061] In this clinical test, the ultrasonic frequency of the ultrasonic therapy equipment is set to about 1MHz and the intensity is about 400mW / cm 2 , and the treatment time is set to 20 minutes. One knee was selected on both sides (left and right) and the gel used for ultrasound treatment was fully applied, the probe was lightly bonded to the affected area, and the run switch was pressed to start the treatment. To assess efficacy, WOMAC survey (Assessment of Pain, Firmness, and Function) was conducted by t...

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Abstract

The present invention relates to an ultrasonic device for the treatment o arthritis, and more particularly, to an ultrasonic device for the treatment or prevention of degenerative arthritis, which is so structured that it generates ultrasonic waves with an intensity of 200-800 mW / cm2 and applies low-intensity ultrasonic energy of 100-400 mW / cm2 to cartilage cells deep in the skin's dermis. The inventive ultrasonic device comprises: a main control unit including an ultrasonic oscillation control unit allowing the generation of ultrasonic waves with a frequency of 0.1-5 MHz and low intensity of 200-800 mW / cm2; an ultrasonic generator for generating ultrasonic waves according to the control state of the main control unit; an ultrasonic vibrator that vibrates according to ultrasonic waves inputted from the ultrasonic generator; and a probe for transferring ultrasonic vibration to a joint to be treated. The ultrasonic device can induce the regeneration of cartilage tissue by the activation of cartilage tissue, and thus, can fundamentally treat degenerative arthritis.

Description

technical field [0001] The present invention relates to an ultrasonic instrument for treating arthritis, more specifically, relates to an ultrasonic instrument for treating or preventing degenerative arthritis. 2 Ultrasound, and the intensity is 100-400mW / cm 2 The low-intensity ultrasound acts on the deep chondrocytes of the skin dermis. Background technique [0002] Degenerative arthritis, known by many names, including osteoarthritis and senile arthritis, is a disease that occurs when the cartilage in a joint is destroyed, creating an uneven surface or when the cartilage is damaged by prolonged weight bearing on the joint. Damage to the smooth surface of the articular cartilage, where the bluish-white, shiny substance meets the end of the bone. [0003] Structures where two or more bones are connected to each other in a movable manner are often called "joints." Articulated parts include knees, jaws, shoulders, hips, fingers, toes, elbows, necks, and vertebrae. The bony ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61N7/00
CPCA61N7/00
Inventor 闵炳铉朴素罗
Owner DUPLOGEN INC
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