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Production of slow-releasing capsule in treatment of pelvic inflammatory disease

A slow-release capsule and production method technology, which is applied in the direction of pharmaceutical formulations, medical preparations containing active ingredients, drug delivery, etc., can solve the problems of undisclosed content and drug preparation methods, etc., so as to improve the pain threshold of hot plate reaction, enhance the Effects of peritoneal macrophage phagocytosis and promotion of lymphocyte transformation

Active Publication Date: 2007-11-21
广西葛洪堂药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, the above-mentioned published articles only disclose part of the pharmaceutical ingredients, and do not disclose the content and the preparation method of the medicine. That is to say, the pharmaceutical product for the treatment of pelvic inflammatory disease of the present invention and the preparation method are not fully disclosed in the literature.

Method used

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  • Production of slow-releasing capsule in treatment of pelvic inflammatory disease
  • Production of slow-releasing capsule in treatment of pelvic inflammatory disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0078] Weigh the following traditional Chinese medicine ingredients (unit: g)

[0079] Golden cherry root 18.8; Millipeda 32.7; Qianjinba 18.1; Gongluomu 18.3; LMZ 7.5;

[0080] Its production steps are:

[0081] (1) Take 2.1 g of the total amount of Andrographis paniculata, pulverize it into fine powder with superfine pulverization technology, and sterilize it with high-pressure steam at 100-120° C. for 30-60 minutes to obtain intermediate product A;

[0082] (2) Get remaining Andrographis paniculata 4.5g soak 1 hour with the ethanol of volume concentration 60-80%, carry out reflux alcohol extraction, the solution after alcohol extraction reclaims ethanol, obtains alcohol extraction part B;

[0083] (3) Gongluomu and Liangmianzhen were decocted twice, each time for 2 to 3 hours, filtered the medicinal solution, combined with the extracted solution twice, and concentrated to obtain the water-extracted part C;

[0084] (4) Boil Rosa japonica root, Spatholobus Spatholobus, and...

Embodiment 2

[0088] Weigh the following traditional Chinese medicine ingredients (unit: g)

[0089] Golden Cherry Root 8, Millipede 15, Qianjinba 8, Gonggongmu 8, LMZ 3, Andrographis 2.5;

[0090] Its production steps are:

[0091] (1) Take 0.8 g of the total amount of Andrographis paniculata, pulverize it into fine powder with superfine pulverization technology, and sterilize it with high-pressure steam at 100-120°C for 30-60 minutes to obtain intermediate product A;

[0092] (2) Get 1.7 parts by weight of the remaining Andrographis paniculata and soak it in ethanol with a volume concentration of 60-80% for 1 hour, carry out reflux alcohol extraction, and recover ethanol from the solution after alcohol extraction to obtain alcohol extraction part B;

[0093] (3) Gongluomu and Liangmianzhen were decocted twice, each time for 2 to 3 hours, filtered the medicinal solution, combined with the extracted solution twice, and concentrated to obtain the water-extracted part C;

[0094] (4) Boil R...

Embodiment 3

[0098] Weigh the following traditional Chinese medicine ingredients (unit: g)

[0099] Golden cherry root 23.4; Millipeda 38.8; Qianjinba 22.9; Gongluomu 23.2;

[0100] Its production steps are:

[0101] (1) Take 3 g of the total amount of Andrographis paniculata, grind it into fine powder, and sterilize it with high-pressure steam at 100-120° C. for 30-60 minutes to obtain intermediate product A;

[0102] (2) Take the remaining 5.1g of Andrographis paniculata, together with the weighed golden cherry root, Caulis Spatholobus, Qianjinba, Gongluomu, and Liangmianzhen, add 5 to 8 times the amount of water, decoct twice, each time for 2 to 3 hours, medicine Liquid was filtered, and the two boiling extracts were combined to obtain the water extraction part B;

[0103] (3) Concentrate B, dry it, and pulverize it into a fine powder to obtain the intermediate product dry cream powder C;

[0104] (4) Mix the intermediate products A and C, granulate, mix with appropriate amount of au...

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Abstract

The invention is concerned with the method of preparation of the capsule for pelvic inflamatroy disease therapy that is in dry cream form extracts from leatherleaf milletia, creat, leatherleaf mahonia, prickly ash, Qianjin Stubbs, and cherry-kan by ethanol or water, adds into 0.5-5% spermaceti wax or other retarder dressing and separates into 2,4,6,8 hours releasing pills with different identify colors and mixes into empty capsule, pack the pilles into boxes to get the final products.

Description

technical field [0001] The invention relates to a medicament for treating pelvic inflammatory disease, in particular to a medicament for treating endometritis and adnexitis with damp-heat syndrome and a production method thereof. Background technique [0002] Pelvic inflammatory disease refers to the inflammation of female internal genitalia and its surrounding connective tissue and pelvic peritoneum, which can be divided into acute and chronic types. Ovarian inflammation, pelvic connective tissue inflammation, and pelvic peritonitis, among which salpingo-oophoritis is the most common, can lead to inflammation when the body's immune function declines, endocrine changes, or exogenous pathogenic bacteria invade. Endometritis is an inflammation caused by pathogens invading through the detachment surface of the placenta and spreading to the decidual layer of the uterus, which mostly occurs in uterine surgery, abortion and postpartum; Adhesion and periovarian inflammation occurs...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/758A61K9/52A61P15/00
Inventor 苏作林邓向东廖展苇
Owner 广西葛洪堂药业有限公司
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