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Medicine for treating dumps emotional handicap type disease

A technology for emotional disorders and drugs, applied in drug combinations, nervous system diseases, pharmaceutical formulations, etc., can solve problems such as lower patient compliance, unacceptable patient acceptance, and increased toxic reactions, so as to weaken adverse reactions, facilitate administration, and stabilize mood Effect

Inactive Publication Date: 2007-12-05
张宝山
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the effective dose curves of these drugs are positively crossed with their own toxicity response curves, that is to say, when the drug reaches the effective dose, its toxic response also increases, resulting in a decrease in patient compliance
selective serotonin reuptake inhibitors (SSRIs) s ) also has different degrees of adverse reactions, and the price is expensive, which is difficult for most patients to accept

Method used

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Examples

Experimental program
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preparation example Construction

[0046] The preparation method of the capsule of the medicine of the present invention is, at first prepare the plant Chinese herbal medicine extract, weigh each raw material of the plant Chinese herbal medicine according to the proportion, cut or smash after washing, add water and immerse, put rhubarb alone, after soaking for 2 to 3 hours, Decoct for 1-2 hours (after decocting for 0.5-1 hour, add rhubarb), filter, and take out the filtrate; then add water, decoct for 1-2 hours, filter, and combine the two filtrates. Concentrate the combined filtrate by a low-temperature vacuum method, dry it to a thick paste, grind it into fine powder, pass it through a 80-100 mesh sieve, and set aside.

[0047] Then, the powdered clomipramine, sulpiride, sodium valproate, borneol and pulverized plant Chinese herbal extracts are fully stirred evenly according to the proportioning ratio to prepare the medicine of the present invention.

[0048] The above-mentioned stirred medicine can be put in...

Embodiment 1

[0076] 1. Weigh 750g of Rhizoma Cyperi, 450g of Dannanxing, 750g of Suanzaoren, 600g of Shichangpu, 900g of Rhubarb, 600g of Albizia Albizia, 500g of Noctilucia, 750g of Epimedium, 450g of Citrus aurantium, 450g of Bupleurum, 750g of Schisandra, and 500g of Angelica , peach kernel 450g, Chuanxiong 450g, rinse and cut or mash, add pure water to soak for 2 hours, put the rhubarb alone, decoct for 1.5 hours (after decocting for 1 hour, add yellow), filter, take out the filtrate; add pure water to the medicinal residue Boil for another 1 hour, filter, and combine the two filtrates. Concentrate the combined filtrate under low-temperature vacuum to a thick paste, dry, pulverize, pass through a 100-mesh sieve, and set aside.

[0077] 2. Accurately weigh 16.7g of powdered clomimethazine, 22.3g of sulpiride, 22.3g of sodium valproate, 20g of borneol, and 918.7g of crushed traditional Chinese medicine extract, and mix well.

[0078] 3. Fill capsules with 450mg per capsule.

[0079] Fo...

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Abstract

The medicine for treating depression and other mental disturb diseases is prepared with chlorimipramine, sulpiride, sodium valproate, borneol and Chinese herbal medicine extractum prepared with nutagrass flatsedge rhizome, arisaema with bile, wild jujube seed and other Chinese medicinal materials. The medicine consists of chemically synthetic medicine and Chinese herbal medicine component, and has synergistic treating effect, less toxic side effect, and good patient's compliance.

Description

technical field [0001] The present invention relates to a kind of medicine that is used for the treatment of depressive mood disorders such as depression, sleep disorder, obsessive-compulsive symptoms, neurasthenia, climacteric syndrome, chronic fatigue syndrome, specifically a kind of chemically synthesized medicine and plant Chinese herbal medicine It is a combined drug for calming the nerves, regulating qi and relieving depression. Background technique [0002] Depression, sleep disorders, obsessive-compulsive symptoms, neurasthenia, climacteric syndrome, chronic fatigue syndrome and other depressive mood disorders are common and frequently-occurring diseases that endanger human physical and mental health. As far as depression is concerned, its lifetime prevalence rate is 6.1% to 9.5%, and patients have to see a doctor repeatedly, thus causing a serious economic burden. In addition, it will reduce the labor capacity of patients. As for the mental pain brought to the pat...

Claims

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Application Information

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IPC IPC(8): A61K36/8905A61K9/14A61K9/20A61K9/48A61P25/24
Inventor 张宝山马和增褚会英张敏
Owner 张宝山
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