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Use of thyroid hormone conversion inhibitors

A thyroid hormone and inhibitor technology, applied in the field of topical mixtures, can solve problems such as difficulty in topical treatment of psoriasis

Inactive Publication Date: 2007-12-19
TRUSTEES OF BOSTON UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Not only is moderate to severe psoriasis relatively difficult to treat locally, but systemic therapy or radiotherapy is often required due to its chronic and relapsing nature

Method used

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  • Use of thyroid hormone conversion inhibitors
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  • Use of thyroid hormone conversion inhibitors

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Abstract

The present invention is directed to the use of thyroid hormone conversion inhibitors to treat hyperproliferative skin disorders, preferably their use in topical admixtures.

Description

field of invention [0001] [001] This application claims the benefit of U.S. Provisional Application U.S.S.N.60 / 606,481, filed September 1, 2004, under 35 U.S.C.§119(e) of the United States. [0002] [002] The present invention relates to the use of an inhibitor of thyroid hormone conversion in the treatment of hyperproliferative skin diseases, preferably in a topical mixture. Background of the invention [0003] [003] A number of diseases are associated with cellular hyperproliferation, including psoriasis, ichthyosis, cancer, and viral infections of the skin. For example, psoriasis is a chronic inflammatory disease characterized by hyperproliferation and abnormal differentiation of keratinocytes. [0004] [004] Psoriasis is one of the most common skin diseases, affecting as many as 1-2% of the world's population. It is characterized by well-defined erythematous papules and circular plaques covered with silvery-white mica flaky scales. Different degrees of pruritus appear...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K49/04
CPCA61K31/60A61K31/192A61K31/198A61K31/138A61K31/196A61P17/00A61P17/06A61P17/12A61P29/00A61P35/00A61P37/00A61P43/00A61P5/16
Inventor J·D·萨菲尔M·F·霍利克
Owner TRUSTEES OF BOSTON UNIV