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Skin-condition improving composition comprising vaccinium uliginosum extract and method for preparation thereof

A technology for improving skin and bilberry. It is applied in skin care preparations, medical preparations containing active ingredients, and drug combinations. It can solve the problem of unknown skin whitening effects and difficult transdermal absorption of polymers. Collagen, can not fully predict the function and other problems, to achieve the effect of preventing and removing skin wrinkles, preventing skin photoaging, and promoting the improvement of wrinkle conditions

Active Publication Date: 2008-01-09
UNIV IND COOP GRP OF KYUNG HEE UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, if collagen is applied to the skin surface in the form of cosmetics, there is a problem that it is difficult to absorb polymer collagen percutaneously, so that its function cannot be fully expected
However, the effects of bilberry on skin wrinkling and skin lightening are not known

Method used

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  • Skin-condition improving composition comprising vaccinium uliginosum extract and method for preparation thereof
  • Skin-condition improving composition comprising vaccinium uliginosum extract and method for preparation thereof
  • Skin-condition improving composition comprising vaccinium uliginosum extract and method for preparation thereof

Examples

Experimental program
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Effect test

preparation example 1

[0066] Preparation Example 1: Preparation of Bilberry Extract

[0067] In a water bath at 50° C., 100 g of bilberry fruit collected from Bukhan, Korea, and 500 ml of 80% water were heated together for 12 hours to obtain a vaccinium extract. The vaccinia extract was filtered through multiple layers of gauze and the supernatant was collected. The supernatants obtained by repeating the extraction and filtration process 3 times were combined together, and the water contained in the combined supernatants was completely evaporated under reduced pressure with a rotary evaporator to obtain a concentrated hot water extract .

preparation example 2

[0068] Preparation Example 2: Preparation of Bilberry Extract Powder

[0069] The concentrated Vaccinium bilberry extract was dissolved in distilled water and then spray-dried to obtain the final Vaccinium vaccinium extract in powder form.

preparation example 3

[0070] Preparation Example 3: Preparation of Bilberry Extract

[0071] 100 g of Vaccinium cranberry fruit was added to 500 ml of 80% methanol (methanol: water = 4: 1), and ultrasonic treatment was performed 4 times at room temperature to obtain an extract. The extract will be filtered through gauze and the supernatant collected. Supernatants obtained by repeating the extraction and filtration process 3 times were combined together, and methanol contained in the combined supernatants was evaporated under reduced pressure using a rotary evaporator. The residual extract was dissolved in a small amount of distilled water to obtain an alcoholic extract of Vaccinium cranberry.

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Abstract

The present invention relates to a composition for the improvement of skin conditions, comprising an extract of Vaccinium uliginosum as an active ingredient. The Vaccinium uliginosum extract has the effects of inhibiting and scavenging reactive oxygen species produced in skin tissue as a result of ultraviolet irradiation to the skin, effectively inhibiting tyrosinase activity to inhibit the production of melanin in melanin cells, inhibiting the secretion of cytokines in keratinocytes, promoting the production of procollagen, and inhibiting the decomposition of collagen. Thus, the extract will be useful for the prevention of skin photo aging caused by ultraviolet radiation, the enhancement of skin whitening and the improvement of wrinkles. In addition, the Vaccinium uliginosum extract is suitable to use as a component for improving skin wrinkles in cosmetics, foods and drugs, because the Vaccinium uliginosum extract can achieve the effect of improving skin conditions, even when it is applied to the skin or used internally.

Description

technical field [0001] The present invention relates to a composition for improving skin condition, which composition contains Vaccinium uliginosum L. extract, more particularly, the present invention relates to a composition for improving skin condition (skin aging), The composition can prevent and improve skin discoloration, freckles, pigmentation, etc., promote skin whitening, prevent and remove skin wrinkles, and improve skin elasticity. The composition of the present invention for improving skin condition can be easily prepared in the form of extract or dried extract powder, and can be used as a component of cosmetics, functional health food, medicine, etc. for improving skin condition. Background technique [0002] Recently, as the average life expectancy increases and the elderly population increases, research on aging in the fields of medicine, biology, and food is gradually increasing. All living organisms age because of aging, which means that the organism's abili...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61Q19/02A61Q19/08
CPCA61K2800/522A61K8/97A61K36/45A61K2800/782A61Q19/02A61Q19/08A23L1/3002A23L33/105A61K8/9789A61P17/16A61P17/18A61P43/00A23V2002/00A23V2200/318A61K8/602A61Q17/04
Inventor 丁世荣
Owner UNIV IND COOP GRP OF KYUNG HEE UNIV
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