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A externally use nebula pressurized spray for treating ulcer and solar dermatitis of dermatosis

A technology for sprays and skin diseases, which is applied to skin diseases, medical preparations containing active ingredients, organic active ingredients, etc. It can solve problems such as inappropriate treatment of skin ulcers, restrictions on the use of drugs, and insufficient stability of curative effect. Low cost, short course of treatment, quick effect

Inactive Publication Date: 2008-04-09
BEIJING UNION GENIUS PHARMA TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prevention and treatment of skin diseases, there is no ideal drug treatment for skin ulcers, especially leprosy ulcers and solar dermatitis. At present, hormone therapy is used for clinical treatment of such diseases, but the curative effect is not stable enough and the side effects are large. The dosage forms such as ointment, powder and liniment in traditional Chinese medicine are not suitable for the treatment of skin ulcers, which limits the use of such drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Take 5g of comfrey and 10g of mint, grind them, and reflux extract with 5 times the volume of 50% ethanol for 3 hours, and use the extracted solution and medicinal residues for later use; take Folium Isatidis and grind them, mix them with the medicinal residues from the previous step, and add 5 times the volume of water Boil and extract for 2 hours, filter the medicinal dregs and add 2 times the volume of water for extraction for 3 hours, filter the medicinal residues and add 2 times the volume of water for extraction for 4 hours, combine the three extracted aqueous solutions, filter, heat and concentrate the filtrate to the original volume 1 / 5, cooled, combined with ethanol extracts of comfrey and peppermint, added 15g of high-ester catechins, mixed evenly, and filled.

Embodiment 2

[0019] Take 40g of comfrey and 50g of mint, grind them, and reflux extract with 8 times the volume of 70% ethanol for 5 hours, and use the extracted solution and medicinal residues for later use; take Folium Isatidis and grind them, mix them with the medicinal residues from the previous step, and add 8 times the volume of water Boil and extract for 3 hours, filter the dregs and add 4 times the volume of water and extract for 3 hours, filter and take the dregs and add 3 times the volume of water for extraction for 4 hours, combine the three extracted aqueous solutions, filter, heat and concentrate the filtrate to the original volume 1 / 3, cooled, combined with the ethanol extracts of comfrey and peppermint, added 50g of high-ester catechins, mixed evenly, and filled.

Embodiment 3

[0021] Take 28g of comfrey and 30g of mint, grind them, and reflux extract with 7 times the volume of 65% ethanol for 5 hours, and use the extracted solution and medicinal residues for later use; take Folium Isatidis and grind them, mix them with the medicinal residues from the previous step, and add 6 times the volume of water Boil and extract for 3 hours, filter the medicinal dregs and add 3 times the volume of water to extract for 3 hours, filter and take the medicinal residues and add 4 times the volume of water and extract for 4 hours, combine the three extracted aqueous solutions, filter, heat and concentrate the filtrate to the original volume 1 / 4, cooled, combined with the ethanol extracts of comfrey and peppermint, added 30g of high-ester catechins, mixed evenly, and filled.

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Abstract

The invention discloses medicine preparation for treating dermatoses of helcosis and solar dermatitis and the preparation process of the spraying agent thereof. The spraying agent for external use for preventing and treating the dermatoses of helcosis and solar dermatitis is produced by applying high ester type catechin, matching three kinds of natural medicines of Asian puccoon, peppermint and syers woad leaves to compose compound, and adopting a plurality of advanced preparation technology. The process has the concrete steps that after being pulverized, the Asian puccoon and the peppermint are extracted through reflux with ethyl alcohol, the gruffs are mixed with the pulverized syers woad leaves, the mixture is boiled by adding water and is extracted for three times, the water extracting solution in the three times is combined together, filtered, and mixed with the ethyl alcohol extracting solution of the Asian puccoon and the peppermint after filter liquid is concentrated, then the high ester type catechin is added, separate packaging and spray can charging are performed, and thereby the spraying agent is produced. The medicine preparation has the advantages of high efficiency and non toxicity. The medicine effect is exerted rapidly, the raw materials mentioned in the invention are cheap and available, and have low cost.

Description

technical field [0001] The invention discloses a pharmaceutical preparation and a preparation method thereof, in particular to an externally used medicine for treating skin ulcers and solar dermatitis and a preparation process of a spray thereof, which belongs to the field of biomedicine. Background technique [0002] The content of tea polyphenols in tea is generally 15% to 20%. Among the components of tea polyphenols, flavanols are the main ones, and catechins are the main flavanols. The content of catechins accounts for about 70% of the total tea polyphenols, and catechins are mainly composed of monomer catechin (C), epicatechin (EC), epigallocatechin (EGC), Composition of Epigallocatechin Gallate (ECG), Epigallocatechin Gallate (EGCG). In the past 30 years, researchers at home and abroad have discovered that tea polyphenols contained in tea have various pharmacological effects such as anti-oxidation, anti-tumor, anti-ultraviolet radiation damage, and anti-allergy. Con...

Claims

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Application Information

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IPC IPC(8): A61K36/534A61P17/02A61P17/00A61K31/352
Inventor 李楠韩国柱张维英王爱平王英明王童单永超
Owner BEIJING UNION GENIUS PHARMA TECH
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