Coated fabric containing antibiotic peptides and preparation method thereof

A technology for coating fabrics and antimicrobial peptides, which is applied in the fields of peptides, plant fibers, textiles, and papermaking, and can solve problems such as microbial resistance, skin irritation, and discoloration of antibacterial agents

Inactive Publication Date: 2008-07-23
HANGZHOU WENSLI SILK TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Taking the processing of synthetic fibers of silver-containing zeolite antibacterial materials as an example, the processing must be realized through antibacterial masterbatch technology. More importantly, it is necessary to prevent the discoloration of antibacterial agents, because generally silver-containing antibacterial Discoloration in molded products; on the other hand, although the antibacterial effect of organic antibacterial agents is strong, they are highly toxic, and many organic antibacterial agents have other side effects, such as irritation to the skin, etc. Long-term use of organic antibacterial agents can also cause microorganisms Risk of drug resistance and mutation

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Dissolve 0.1 gram of Protegrins, an antimicrobial peptide derived from porcine leukocytes prepared by the laboratory, in 500 grams of polyurethane solution diluted to 2%, and then immerse the polyester fabric in the above solution with a bath ratio of 1:50 and soak for 10 minutes at room temperature. Minutes, two dipping and two rolling, the excess rate is 100%, then pre-baking (70°C, 20 minutes), baking (130°C, 5 minutes), soaking in water for 10 minutes, and drying to obtain polyester containing antimicrobial peptides fabric. The polyester fabric can effectively kill 93.7% of Escherichia coli E.coli and 89.7% of Staphylococcus aureus S.aureus.

[0024] Antibacterial test method:

[0025] Take the coated fabrics and uncoated fabrics containing antimicrobial peptides with a diameter of 1 cm, sterilize them with ultraviolet radiation (irradiation time is 30 minutes), and infiltrate them with sterile water; put the samples into sterile cell culture dishes respectively, a...

Embodiment 2

[0027] Dissolve 1.5 grams of the antimicrobial peptide Protegrins derived from porcine leukocytes prepared by the laboratory in 500 grams of polyurethane solution diluted to 2.5%, then soak the knitted cotton cloth in the above solution, the bath ratio is 1:50, and soak at room temperature. 8 minutes, double soaking and second rolling, the remaining rate is 100%, then pre-baking (70°C, 25 minutes), baking (130°C, 6 minutes), soaking in water for 8 minutes, and drying to obtain antimicrobial peptides. Knitted cotton fabric. The knitted cotton fabric can effectively kill 95.9% of Escherichia coli E.coli and 92.3% of Staphylococcus aureus S.aureus.

Embodiment 3

[0029] Dissolve 0.06 gram of commercially available antimicrobial peptide Protegrins in 500 grams of cross-linkable polyacrylate toluene solution diluted to 1.6%, glass transition temperature Tg of 0 ℃, then the wool / acrylic fiber blended fabric is immersed in the above solution, The bath ratio is 1:50, soaking at room temperature for 10 minutes, two dipping and two rolling, the rolling rate is 100%, then pre-baking (70°C, 20 minutes), baking (130°C, 6 minutes), soaking in water for 10 minutes, After drying, the wool and acrylic blended fabric containing antimicrobial peptides is obtained. The wool nitrile blended fabric can effectively kill 93.1% of Escherichia coli E.coli and 90.6% of Staphylococcus aureus S.aureus.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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Abstract

The invention discloses a coated fabric containing antibacterial peptides and the preparation method, the surface of the fabrics are coated with coating agents containing antibacterial peptides. The preparation method comprises as follows: firstly, the antibacterial peptides are dissolved or dispersed into the coating agents at normal temperature to form finishing agents, then the fabrics are coated by the conventional rolling-baking method. The coated fabric containing antibacterial peptides has the advantages of broad spectrum antibacterial and bactericidal effect because the surface of the fabrics are coated with coating agents containing antibacterial peptides; no obvious influence on the appearance of the fabrics due to the thin coating layer.

Description

technical field [0001] The invention belongs to the field of textiles, in particular to a coated fabric containing antimicrobial peptides and a preparation method thereof. Background technique [0002] In most parts of our country, especially our Zhejiang province, the climate is relatively humid, which is very suitable for the reproduction and growth of microorganisms, and symptoms such as bedsores often appear. On the other hand, in some public places, such as hospitals, bedding and mattresses contaminated by patients' pus, blood, urine, stool and exudate, etc., have become places for the growth and reproduction of various microorganisms, creating a barrier for hospital cross-infection and infection. hidden dangers. Therefore, textile fabrics with antibacterial function play an extremely important role in preventing the invasion of germs. On the one hand, it can protect people who use textiles, prevent the reproduction of various bacteria and fungi, and prevent the spread...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): D06M16/00C12S11/00C07K7/08D06M15/263D06M15/564D06M101/06D06M101/32D06M101/20D06M101/34
Inventor 马廷方孙国君姚菊明
Owner HANGZHOU WENSLI SILK TECH
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