Collecting device of exhaled breath condensate (EBC)

A technology for exhaled breath condensate and collection device, which is applied in sampling devices, medical science, sensors, etc., can solve the problems of unseen setting technology, affecting analysis quality, and troublesome operation.

Inactive Publication Date: 2008-08-13
JILIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The residual saliva remains at the lower end of the T-shaped tube. When taking out the residual saliva, the T-shaped tube needs to be removed from the device, which is cumbersome to operate, and it is easy to cause artificial interference to EBC and affect the quality of analysis; at the same time, t

Method used

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  • Collecting device of exhaled breath condensate (EBC)
  • Collecting device of exhaled breath condensate (EBC)
  • Collecting device of exhaled breath condensate (EBC)

Examples

Experimental program
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Effect test

Embodiment 1

[0030]Four-way pipe 5 can adopt hard material, as materials such as metal, glass, nontoxic plastics, present embodiment adopts glass material; The four outlets of the four outlets are connected respectively with the replaceable air inlet nozzle 1, the suction one-way valve 3, and the exhalation one-way valve 4 saliva residue collection container 17, wherein the replaceable air inlet nozzle 1 is replaced with a new one every time it is used. Sexually used parts; the second outlet of the four-way tube 5 and the inspiratory one-way valve 3 connected thereto control the patient's inspiratory passage; the third outlet of the four-way tube 5 and the exhalation one-way valve 4 connected thereto collect The exhaled breath of the patient makes it one-way connected to the refrigeration chamber 8; the fourth outlet of the four-way pipe 5 and the residual saliva collection vessel 17 connected to it collect and use the residual saliva of the patient to prevent the residual saliva of the pat...

Embodiment 2

[0040] "Claw-shaped" four-way pipe 18 can be made of hard materials, such as metal, glass, non-toxic plastics and other materials. In this embodiment, glass material is used; the pipe diameter is 8-20 mm, so that breathing is unobstructed. In this embodiment, 10 mm is used; The four outlets of the "claw-shaped" four-way pipe 18 are respectively matched to connect the replaceable air inlet nozzle 1, the suction check valve 3, and the exhalation check valve 4 saliva residual fluid collection container 17, wherein the replaceable inlet nozzle 1 is It is a one-time use part; the second outlet of the "claw" four-way pipe 18 and the suction check valve 3 connected thereto control the patient's inspiratory channel; the "claw" four-way pipe 18 The third outlet of the "claw" four-way pipe 18 and the connected exhalation one-way valve 4 collect the exhaled air of the patient and make it one-way connected to the cooling chamber 8; the fourth outlet of the "claw" four-way pipe 18 and the s...

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Abstract

The invention relates to a EBC detection as a detection technique completely without wound, with important use value for airway inflammation. A fourway gaspath solves the automatic separation of entrance of expired air, exit of expired air, inspired air and spit residue. The upbending design and 'claw type' of the exit pipeline of the expired air can solve the effect of spit residue from the expired air on refrigeration area. A singlechip system detects the expired air amount and the condensing temperature is set to quantify the collection of the condensate of expired air, so as to quantitatively evaluate change and degree of states such as oxidation stress, inflammation and the like in airway of a variety of respiratory disease.

Description

Field of invention: [0001] The present invention relates to a medical detection front-end device, which is an exhaled air condensate (EBC) collection device capable of monitoring the exhaled gas flow rate, so as to facilitate the detection of biochemical indicators in the later stage of the collected EBC to evaluate the severity of various respiratory diseases. Changes and degrees of oxidative stress and inflammatory state in the airway. Background technique: [0002] At present, the specimen collection methods used to detect airway secretions in inflammatory respiratory diseases mainly include sputum collection and bronchoalveolar lavage fluid collection. Among them, sputum collection includes ordinary sputum samples and induced sputum samples. As we all know, in many cases, limited by the specific conditions of patients, it is difficult for ordinary sputum samples to meet the requirements of clinical testing. For example, some patients have symptoms of little or no sputum...

Claims

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Application Information

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IPC IPC(8): A61B5/097G01N1/22
Inventor 华树成赵静李丹凌振宝吕晓红林乡山刘振华王君
Owner JILIN UNIV
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