Externally-applied plaster of bullatacin for resisting acquired immuno-deficiency syndrome virus

An anti-AIDS and virus technology, applied in the direction of antiviral agents, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. , The effect of strong drug load capacity and strong air permeability

Active Publication Date: 2014-03-19
贵州正鑫实业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The technical problem to be solved by the present invention is to provide a kind of external-use patch of bratasine anti-AIDS virus, which has not only solved the shortcomings of the previous oral or intravenous administration of anti-tumor drugs, but also overcomes the disadvantages of traditional external-use patches. It has the disadvantages of high skin irritation and certain toxicity, and reduces the economic cost

Method used

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  • Externally-applied plaster of bullatacin for resisting acquired immuno-deficiency syndrome virus
  • Externally-applied plaster of bullatacin for resisting acquired immuno-deficiency syndrome virus
  • Externally-applied plaster of bullatacin for resisting acquired immuno-deficiency syndrome virus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1: the external-use patch of bratasine anti-AIDS virus, it comprises backing layer, drug storage and anti-adhesive layer, selects the good cotton medical non-woven fabric of ventilation to be backing layer, and drug storage is with high Molecular gel acrylate pressure-sensitive adhesive is used as an adhesive agent, which contains a prepared pratasine liquid, and a polyester film treated with silicone oil as an anti-adhesive layer.

[0029] Bratasine medicinal solution is to dissolve 198 grams of Bratasine partial drug essence in 1100ml mixture of absolute ethanol and propylene glycol with a volume ratio of 1:1, fully stir, mix evenly, and make an external patch 20400 patches (Size: 7×10cm).

Embodiment 2

[0030] Embodiment 2: the preparation method of the external-use patch of bratasine anti-AIDS virus, it comprises the following steps: (1) batching: 198 grams of bratasine local drug essence are dissolved in the anhydrous 1:1 volume ratio In the 1100ml mixed liquid of ethanol and propylene glycol, fully stir, make it mix evenly; (2) glue making: adopt the production technology of acrylate pressure-sensitive adhesive to make pressure-sensitive adhesive; The mixed solution of medicine essence, absolute ethanol and propylene glycol is mixed with the heated and melted pressure-sensitive adhesive, coated on the anti-adhesive layer, and then covered with the backing layer; (4) Slicing: cut into a suitable size (5× 7cm, 7×10cm, 9×12cm and other specifications); dry and cool, sealed with aluminum-plastic composite film.

Embodiment 3

[0031] Embodiment 3: The beneficial effect of medicine described in the present invention is further set forth below by drug clinical trial:

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PUM

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Abstract

The invention discloses an anti-AIDS virus bullatacin patch for external use, which comprises a backing layer, a drug reservoir and an anti-sticking layer; a cotton medicinal non-woven fabrics with good permeability is used as the backing layer, a polymeric gel (an acrylate pressure-sensitive gel) as an adhesive; the patch comprises the prepared liquid of bullatacin, and a silicone-oil anti-sticking polyester film is functioned as an anti-sticking layer. The patch for external use has the advantages that not only the disadvantage of serious harmful and side effects of the existing oral or intravenous antitumor drug are solved, but also the disadvantage of heavy skin irritation and a certain extend of toxicity of traditional patches for external use are overcome, and the economic cost is reduced.

Description

technical field [0001] The invention relates to an anti-AIDS virus external drug preparation, in particular to an anti-AIDS virus external patch. Background technique [0002] AIDS, the medical full name is "acquired immunodeficiency syndrome", is an infectious disease caused by human immunodeficiency virus, also known as AIDS virus. HIV, or HIV for short, is a virus that attacks the human immune system. It takes the most important T4 lymphocytes in the human immune system as the target of attack, and swallows and destroys T4 lymphocytes in large quantities, thereby destroying the human immune system, and finally causing the immune system to collapse, causing the human body to develop disease due to loss of resistance to various diseases and die. In recent years, AIDS has spread more and more rapidly around the world, seriously threatening human health and social development, and has become the fourth biggest killer threatening people's health. [0003] The HIV reproducti...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/70A61K31/7048A61K47/32A61K47/34A61P31/18
Inventor 杨正强杨仁洲脱冰林周显勇张安袁胜伟
Owner 贵州正鑫实业有限公司
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