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Serositis in duckling vaccine oral liquid synergistic agent for poultry biology and preparation method thereof

A technology of duck serositis and oral liquid, which is applied in the field of poultry pharmaceutical composition and its preparation, can solve the problems of duck serositis, such as uncertainty, limited effect, instability, etc., and achieve the effect of improving the body's immunity

Inactive Publication Date: 2008-12-03
海南正强超越生化技术开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Regarding vaccination, there is no very effective immune prevention and control measures at present. The commonly used vaccine is Escherichia coli and Murray bacillus dual vaccine. The vaccination needs to be injected twice and the effect is very limited and unstable. Meningitis brings great uncertainty

Method used

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  • Serositis in duckling vaccine oral liquid synergistic agent for poultry biology and preparation method thereof
  • Serositis in duckling vaccine oral liquid synergistic agent for poultry biology and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Embodiment 1: Preparation of Oral Liquid Synergist 1 of the present invention

[0017] (1) Weigh 10 grams of capillary wormwood, 2 grams of Gastrodia elata, 15 grams of Schisandra chinensis, 10 grams of Duyiwei, 20 grams of hawthorn, 10 grams of herb, 10 grams of gentian, 2 grams of snake gall, 10 grams of ox gall, 40 grams of aloe, Rock sugar 25 grams.

[0018] (2) Decoct the raw material twice, add 8 times the amount of water for the first time, decoct for 2 hours, add 6 times the amount of water for the second time, decoct for 1 hour, combine the two decoctions, filter to obtain the filtrate, and concentrate to specific gravity 1.35 extract, add 85-95% edible glacial acetic acid for extraction, recover glacial acetic acid and concentrate, dry at 45-50°C to obtain 14.86 grams of dry extract;

[0019] (3) Grinding the dry extract into powder, adding 5 grams of rifampicin and 5 grams of polymyxin, and stirring evenly;

[0020] (4) Add 85-95% edible glacial acetic acid...

Embodiment 2

[0021] Embodiment two: preparation of oral liquid synergist 2 of the present invention

[0022] (1) Weigh 15 grams of capillary wormwood, 5 grams of Gastrodia elata, 20 grams of Schisandra chinensis, 15 grams of Duyiwei, 20 grams of hawthorn, 15 grams of herb, 15 grams of gentian, 5 grams of snake gall, 20 grams of ox gall, 60 grams of aloe vera, Rock sugar 25 grams.

[0023] (2) Decoct the raw material twice, add 8 times the amount of water for the first time, decoct for 2 hours, add 6 times the amount of water for the second time, decoct for 1 hour, combine the two decoctions, filter to obtain the filtrate, and concentrate to specific gravity 1.35 extract, add 85-95% edible glacial acetic acid for extraction, recover glacial acetic acid and concentrate, dry at 45-50°C to obtain 19.35 grams of dry extract;

[0024] (3) Grinding the dry extract into powder, adding 10 grams of rifampicin and 15 grams of polymyxin, and stirring evenly;

[0025] (4) Add 85-95% edible glacial ac...

Embodiment 3

[0026] Embodiment three: security of the present invention

[0027] 1000 ducks were randomly divided into two groups. Group 1 added 100ml of oral liquid synergist 1 of the present invention in the daily feed of each duck, and group 2 added oral liquid synergist 2 of the present invention. Observation for 30 days.

[0028] In 30 days, all the 1000 ducks had no abnormality, no lack of energy or death, and the growth was good. It shows that the oral liquid of the present invention has good safety performance.

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Abstract

The invention relates to a drug composition for poultry and a preparation method thereof. An oral liquid synergistic agent for duck serositis vaccine is prepared from the following materials by weight portion: 10 to 15 portions of artemisia capillaries, 2 to 5 portions of gastrodia tuber, 15 to 20 portions of schisandra chinensis, 10 to 20 portions of lamiophlomis rotata(benth)kudo, 20 to 25 portions of hawthorn, 10 to 15 portions of atractylodes, 10 to 15 portions of gentian, 2 to 5 portions of snake gall, 10 to 20 portions of ox gall, 40 to 60 portions of aloe, 25 to 40 portions of rock candy, 10 portions of rifampicin and 15 portions of polymyxin. The oral liquid synergistic agent can be fed by being directly mixed with normal feed of the poultry or directly with water drunk by the poultry to effectively improve the immunity of an organism, disease resistant capability and anti-stress capability, lower the ratio of infecting duck serositis and improve the preventing and treating effect of the duck serositis vaccine.

Description

【Technical field】 [0001] The invention relates to a pharmaceutical composition for poultry and a preparation method thereof. 【Background technique】 [0002] Duck serositis is an acute septic infectious disease caused by poultry infected with Riemerella. At present, there are at least 21 serotypes in the world, and there is no cross-immunity between them. The ones that are popular in my country are 1 and 2 Types 1, 6, and 10 are the main types, of which type 1 is the most common. This disease is currently the most common and the most harmful disease in the poultry industry. If it is not treated in time, it often leads to a large number of deaths. In the past, the disease mainly occurred in ducklings less than 5 weeks old. Now, with the enhancement of virulence, ducks of any age are susceptible. Sick ducks are the main source of infection, mainly transmitted through the respiratory tract and digestive tract, and can also be infected. The mortality rate of traumatic wound infec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/12A61K9/10A61P31/04A61P37/04A61K35/58A61K35/413A61K31/496A61K36/8988A61K35/583
Inventor 谢兴荣刘治西唐兆新郭世宁汪连涛王芝武帮勇吴国辉陈胜叶亚多潘永发林仕
Owner 海南正强超越生化技术开发有限公司
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