Chuan Xiong Tea soft capsule and method for preparing the same

A Chuanxiong tea blend and soft capsule technology, which is applied in capsule delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of not fully achieving the efficacy of the original dosage form and affecting the curative effect

Inactive Publication Date: 2008-12-24
北京康业元投资顾问有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the improved dosage form of "Chuanxiong Cha Tiao San" developed at present is especially changed to oral liquid, capsule or granule granule, and a large number of active ingredients in the original decoction are concentrated and improved in clarity. The addition of alcohol precipitation and filtration processes has resulted in the loss of active ingredients. In addition, it is difficult to retain the volatile oils that have the aroma of forsythia and peppermint, which have the effect of promoting blood circulation and removing stasis. Therefore, it directly affects the curative effect. The different active ingredients make the new dosage form of "Chuanxiong Cha Tiaosan" unable to fully achieve the efficacy of the original dosage form.

Method used

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  • Chuan Xiong Tea soft capsule and method for preparing the same
  • Chuan Xiong Tea soft capsule and method for preparing the same
  • Chuan Xiong Tea soft capsule and method for preparing the same

Examples

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Comparison scheme
Effect test

Embodiment 1

[0089] A preparation method of "Chuanxiong Chatiao Soft Capsule", which comprises: firstly weighing various traditional Chinese medicines according to weight ratio, including 200 parts of Chuanxiong, 100 parts of Radix Paeoniae Rubra, 50 parts of Gastrodia elata, 100 parts of notopterygium, 100 parts of Angelica dahurica, 50 parts of pepper, 100 parts of chrysanthemum, 100 parts of mint, 30 parts of windproof, 100 parts of tea, 50 parts of licorice, remove the mud and wash them, put them into a multi-functional Chinese medicine extraction tank, add water and decoct three times, the first time 1- 2 hours, 1-1.5 hours for the second time and the third time respectively; at the same time, collect the volatile oil, combine the decoction liquid extract, and centrifugal filter; concentrate the filtrate under reduced pressure at 60°C to a relative density of 1.05, and then Spray drying to become dry extract powder and pulverize to make it finer than 120 mesh; dissolve the extracted vo...

Embodiment 2

[0091]A preparation method of "Chuanxiong Chatiao Soft Capsule", which comprises: firstly weighing various traditional Chinese medicines according to the weight ratio, including 127 parts of Chuanxiong, 53 parts of Radix Paeoniae Rubra, 21 parts of Gastrodia elata, 42 parts of notopterygium, 42 parts of Angelica dahurica, 10 parts of pungent, 53 parts of chrysanthemum, 84 parts of mint, 15 parts of windproof, 63 parts of tea, 21 parts of licorice, etc., remove the mud and wash them, put them in a multi-functional Chinese medicine extraction tank, add water and decoct three times, the first time 1 -2 hours, 1-1.5 hours for the second time and the third time respectively; at the same time, collect the volatile oil, combine the water decoction extract, and centrifugal filter; concentrate the filtrate under reduced pressure at 60°C to a relative density of 1.05, and then It is spray-dried to become dry extract powder and pulverized so that the fineness is less than 120 meshes; the ...

Embodiment 3

[0093] The preparation method of "Chuanxiong Chatiao Soft Capsule" described in Example 1: First, weigh each herb by weight, including 127 parts of Chuanxiong, 53 parts of Radix Paeoniae Rubra, 21 parts of Tianma, 42 parts of Notopterygium, 42 parts of Angelica dahurica, 10 parts of asarum, 53 parts of chrysanthemum, 5 parts of mint, 15 parts of windproof, 63 parts of tea, 21 parts of licorice and other Chinese medicinal materials, remove the mud and wash them, put them into a multi-functional traditional Chinese medicine extraction tank, add water and decoct three times, 1-2 hours for one time, 1-1.5 hours for the second time and 1.5 hours for the third time; at the same time, collect the volatile oil, combine the decoction liquid extract, and centrifugal filter; concentrate the filtrate under reduced pressure at 60°C to a relative density of 1.05 , and then spray-dry it into dry extract powder and pulverize it so that the fineness is less than 120 mesh; crush aromatic Chinese...

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Abstract

The invention relates to a Chuanxiong Chatiao soft capsule and a preparation method thereof. In modern medicine, the Chuanxiong Chatiao powder is improved and made into tablets, capsule, oral liquid and so on, which can not achieve the efficacy of the original formulation. The preparation method of the Chuanxiong Chatiao soft capsule is that Chuanxiong, red peony root, gastrodia elata, notopterygium, angelica, asarum, chrysanthemum, mint, parsnip, tea leaves, liquorices and catnip are put into the Chinese medicine extraction pot. Water is added for soaking, and the mixture is decocted for three times. At the same time, volatile oil is collected. The water decoction liquid and extraction liquid are combined and processed with centrifugal filtration. The filtrate is decompressed and condensed, and crushed with grain size less than 120 meshes after being processed with spray drying. The extraction volatile oil is melted with a certain amount of edible oil. Dry extractum power is mixed with edible oil. The dry extractum power takes 20-50 weight percent of the oil base in soft capsule. The mixture is grinded by a colloid mill, and pigment gelatin which is taken as capsule wall materialis added and is made into capsule core extractum oil base liquid. The soft capsule is formed by pressing under the condition of stirring. The soft capsule is manufactured after being dried, washed and dried. The Chuanxiong Chatiao soft capsule is used for replacing Chuanxiong Chatiao powder.

Description

Technical field: [0001] The invention relates to the preparation of a traditional Chinese medicine soft capsule, which is a Chuanxiong chatiao soft capsule and a preparation method thereof. Background technique: [0002] "Chuanxiong Tea Tiaosan" comes from the ancient medical book "Taiping Huimin Heji Bureau Prescription". Or headache pain. This prescription can disperse wind and cold, light clear and ascend, dredge collaterals and relieve pain. Treat Taiyang Meridian headache (back headache involving the nape), Baizhi cure Yangming Meridian headache (frontal pain); Asarum, Mint, Nepeta, and Fangfeng Xinsan ascend to evacuate upper wind pathogens, and strengthen the wind-relieving and pain-relieving ability of the three main herbs , and also relieve the exterior and become a ministerial drug; licorice and medicine slow the middle and become an adjuvant drug; clear tea can clear the upper part and lower it, so as to prevent the drugs from being too warm and dry, and rise an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61K9/48A61P29/00
Inventor 邹积宏刘红梅
Owner 北京康业元投资顾问有限公司
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