Chinese medicinal composition for treating disease of stomach

A composition and disease technology, applied in the direction of drug combination, medical raw materials derived from fungi, digestive system, etc., can solve problems that restrict the development and utilization of Hericium erinaceus mycelium

Inactive Publication Date: 2009-03-04
长春白求恩制药有限公司
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  • Abstract
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Problems solved by technology

Although the preparation has shown good curative effect on stomach, duodenal ulcer, chronic gastritis, etc., the extraction, separation and purification methods of active ingredients in mycelia and the basic chemical composition of active ingredients have not been solved. The development and utilization of Hericium erinaceus has been restricted for a long time

Method used

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  • Chinese medicinal composition for treating disease of stomach
  • Chinese medicinal composition for treating disease of stomach

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Embodiment Construction

[0051]Take the pure strain of Hericium erinaceus, culture it on a slant for 7-9 days at 27±1°C, culture it for 5-7 days in a primary shake flask at 27±1°C, and culture it in a secondary shake flask at 27±1°C The seeds are cultured for 5-7 days, cultured in the primary seed tank at 27±1°C for 5-7 days, cultured in the secondary seed tank at 27±1°C for 5-7 days, fermented at 27±1°C for 5-7 days, Heating the fermented liquid at 100°C, filtering, and concentrating into an extract; the medium formula of the slant culture is potato 100: glucose 1: potassium dihydrogen phosphate 1: agar 1; the medium formula of the shake flask culture is glucose 3-4%, 0.03% potassium dihydrogen phosphate, 0.3% peptone, 0.05% sodium chloride, appropriate amount of vitamin B1, appropriate amount of polyether defoamer; the medium formula for seed tank cultivation and fermentation is 0.3% glucose, phosphoric acid Potassium dihydrogen 0.03%, peptone 0.3%, sodium chloride 0.05%, appropriate amount of vitam...

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Abstract

A traditional Chinese medicine combination for the treatment of gastric diseases takes an extract of a herieium captmedusae liquid extract as an active ingredient, and the liquid extract is prepared as follows;a pure strain of herieium captmedusae is taken and carried out the deep culture and the press filtration, then a mycelium is leached by hot water, and leaching liquid is merged with fermentation broth for carrying out the concentration and the drying. The traditional Chinese medicine combination has the advantages that the effective parts are definite, the structure is clear, the dose is less, and the traditional Chinese medicine combination has significant efficacy for treating acute and chronic gastritis, gastric ulcer and chronic atrophic gastritis.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine composition for treating stomach diseases. The extract of Hericium erinaceus extract is used as an active ingredient; the IPC classification number is A61K 36 / 06. Background technique: [0002] The Hericium caput-medusae referred to in the present invention is Hericium caput-medusae, a fungus of the family Dentalaceae, and the fermentation product of its mycelium has been used clinically as a raw material medicine for many years. [0003] Weilexin Granules are medicines made from Hericium erinaceus mycelium culture extract in the Chinese market. Although the preparation has shown good curative effect on stomach, duodenal ulcer, chronic gastritis, etc., the extraction, separation and purification methods of active ingredients in mycelium and the basic chemical composition of active ingredients have not been solved. The development and utilization of Hericium erinaceus has been restricted for a lo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/06A61P1/04
Inventor 李敬轩孙立群刘淑芳李凤才冯屹
Owner 长春白求恩制药有限公司
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