The invention relates to a traditional Chinese medicine composition, particularly a traditional Chinese medicine composition for treating ankylosing spondylitis and a preparation method thereof. The traditional Chinese medicine composition for treating ankylosing spondylitis is prepared from kudzu root, angelica, white peony root, radix rehmanniae preparata, epimedium, Colla Cornus Cervi, Chinese wolfberry, radix psuedostellariae, notopterygium root, heracleum hemsleyanum michaux, red paeonia, cornel, mistletoe, himalayan teasel root, cassia twig, radix salviae miltiorrhizae, spatholobus stem, wolfberry fruit, glossy privet fruit, broomrape, radix achyranthis bidentatae, rhizoma drynariae, cibot rhizome, eucommia, Curculigo orchioides, fleece-flower root, Morinda officinalis, glossy privet fruit, figwort, costus root, hemlock parsley, tuckahoe, Gentiana macrophylla, radix sileris, radix cyathulae, asarum, cassia twig, radix clematidis, prepared szechuan aconite, prepared myrrh, prepared frankincense, licorice and pangolin. The traditional Chinese medicine composition is safe for clinical application, does not stimulate the viscera when being taken orally, is convenient to make and take, ensures the cleanliness of the medicines, is easy for storage, has the advantages of obvious curative effect, many absorbable effective components and favorable drug effect taking, and can treat both the symptoms and root causes; and the total effective rate is up to 97%.