76 results about "Gentiana macrophylla" patented technology

The invention relates to the technical field of cosmetics, and particularly discloses a composition with long-acting moisturizing and repairing effects and application thereof. The composition is prepared from radix gentianae macrophyllae extract, mussel extract, leontopodium alpinum flower / leaf extract and rhizoma anemarrhenae root extract according to the mass ratio of 1: (0.5 to 1.5): (0.7 to 0.9): (0.1 to 0.3). According to the composition, through a multi-path synergistic effect, the gentiana macrophylla extract reduces water loss, the mussel extract constructs a dermis water storage network, the leontopodium alpinum extract enhances water locking and barrier repairing, and the rhizoma anemarrhenae root extract improves the water content of a cuticle. Experiments show that the gentiana macrophylla extract, the mussel extract, the leontopodium alpinum flower / leaf extract and the rhizoma anemarrhenae root extract are combined according to the mass ratio of 1: 1: 0.8: 0.2 for use, and the 8-hour moisturizing rate of the composition is as high as 79.69%. The composition can be added into cosmetics such as essence, emulsion and the like, and has high moisture retention, barrier repairing power and safety.

The invention relates to a traditional Chinese medicine composition for preventing and treating liver rupture syndrome of broiler breeders and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following raw material medicines in parts by mass: 50-200 parts of silybum marianum, 50-200 parts of schisandra chinensis, 50-200 parts of gentiana macrophylla, 50-200 parts of andrographis paniculata, 50-200 parts of radix paeoniae alba, 50-200 parts of oldenlandia diffusa, 50-200 parts of folium isatidis and 50-200 parts of patrinia. The traditional Chinese medicine composition has the effects of resisting endotoxin, inflammation, allergy and liver injury and the like, and effectively prevents and treats the liver rupture syndrome of the broiler breeders.

The invention provides a traditional Chinese medicine composition for treating rheumatic arthritis, a preparation and application, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following medicinal raw materials: 12-18 parts of sailong bone, 6-12 parts of radix aconiti lateralis preparata, 3-9 parts of radix aconiti preparata, 9-15 parts of cassia twig, 1-4 parts of asarum, 9-15 parts of radix clematidis, 20-40 parts of astragalus membranaceus, 3-9 parts of scorpio, 9-15 parts of earthworm, 9-15 parts of caulis sinomenii, 12-18 parts of bighead atractylodes rhizome, 12-18 parts of poria cocos, 9-15 parts of gentiana macrophylla, 12-18 parts of angelica sinensis, 20-40 parts of caulis spatholobi, 9-15 parts of rhizoma drynariae, 12-18 parts of radix paeoniae alba, 3-9 parts of honey-fried licorice root and 6-12 parts of rhizoma zingiberis. According to the traditional Chinese medicine composition for treating rheumatic arthritis, the medicine raw material composition of the traditional Chinese medicine composition for treating rheumatic arthritis is reasonably designed, four pathological links of cold, dampness, stasis and deficiency of rheumatic arthritis are covered through precise compatibility of monarch, minister, assistant and guide, and the traditional Chinese medicine composition has triple curative effects of anti-inflammatory analgesia, immunoregulation and bone protection.

The invention discloses a soothing and repairing gentiana macrophylla extract composition as well as a preparation method and application thereof, and particularly belongs to the technical field of preparation of raw materials of daily necessities. The gentiana macrophylla extract composition is obtained by performing compound solid-state fermentation on gentiana macrophylla through aspergillus oryzae, leuconostoc citreum and saccharomyces cerevisiae and then performing solvent extraction. The gentiana macrophylla extract composition provided by the invention has relatively high oleanolic acid content, which proves that the aspergillus oryzae, the leuconostoc citreum and the saccharomyces cerevisiae can effectively enrich active ingredients in gentiana macrophylla, and meanwhile, the aspergillus oryzae, the leuconostoc citreum and the saccharomyces cerevisiae have a certain synergistic effect on the enrichment of the active ingredients in the fermentation process; the gentiana macrophylla extract composition provided by the invention can effectively inhibit release of inflammatory factors and promote skin repair.

The invention discloses a composition for preventing and treating mastitis and its preparation method and application, including the following components in parts by mass: 10-12 parts of aloe gel, 3-5 parts of berberine tannate and 2-4 parts of gentiana macrophylla extract. The aloe gel and the gentiana macrophylla extract in the present composition are both plant extract ingredients, and both have anti-inflammatory and bactericidal effects. Berberine tannate is a kind of alkaloid, has significant antibacterial effect, and the three are compounded, and the use of antibiotics can be effectively reduced, thereby reducing the residual of antibiotics in animal products, and increasing the safety of product; in addition, aloe gel, gentiana macrophylla extract and berberine tannate have synergistic synergistic effect, and the three are compounded, and mastitis can be effectively treated.

The present invention provides a traditional Chinese medicine composition, a preparation method thereof and an application, belonging to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition of the present invention comprises raw materials in the following parts by weight: 3-5 parts of Atractylodes lancea, 3-5 parts of Gentiana macrophylla, 7-9 parts of Ligusticum chuanxiong, 10-14 parts of Carthamus tinctorius, 3-5 parts of Notopterygium incisum, 10-14 parts of Angelica sinensis, 10-14 parts of Cyathula officinalis, 3-5 parts of Cyperus rotundus, and 7-9 parts of Glycyrrhiza uralensis. Based on the situation of stasis in patients with arthralgia syndrome, the present invention performs drug compatibility for those with stasis in arthralgia syndrome, and has a significant therapeutic effect on arthralgia syndrome caused by wind, cold, dampness and stasis.

The invention discloses a gentiana macrophylla extract, an extraction process and application thereof and a skin care product. The invention belongs to the field of new daily chemical materials, and discloses an extraction process of a gentiana macrophylla extract, which comprises the following steps: step 1, crushing gentiana macrophylla, dispersing the crushed gentiana macrophylla in water, and carrying out enzymolysis by using cellulase to obtain an enzymolysis product; 2, filtering the enzymolysis product, collecting filtrate and filter residues, and drying the filter residues to obtain micro powder; performing vacuum concentration and alcohol precipitation on the filtrate, and collecting to obtain a first extract; step 3, carrying out alcohol extraction on the micro powder once or multiple times, combining extracting solutions, and concentrating the extracting solutions to obtain thick paste; 4, drying the thick paste to prepare powder, so as to obtain a second extract; and step 5, combining the first extract and the second extract to obtain the gentiana macrophylla extract. Through detection, the ratio of loganic acid to gentiopicroside is 1: 3.94, and the compound contains a small amount of swertiamarin, and after related inflammatory factors and other properties are detected, the performance of the compound is better. Meanwhile, the invention also provides related application of the extract.

The invention provides a traditional Chinese medicine preparation for cerebral arterial thrombosis, and belongs to the technical field of traditional Chinese medicine pharmacy, the traditional Chinese medicine preparation is prepared from gentiana macrophylla, divaricate saposhnikovia root, mulberry leaf, radix scrophulariae, ruddle, bulbus fritillariae cirrhosae, bamboo juice, selfheal, poria with hostwood and szechwan chinaberry fruit, and the whole formula has the effects of calming liver and suppressing yang, calming endogenous wind and relieving convulsion, eliminating phlegm and inducing resuscitation. The traditional Chinese medicine preparation has a remarkable improvement effect on the neurological function of a cerebral ischemia reperfusion injury model rat, can effectively reduce the water content of the brain tissue of the rat and the cerebral infarction volume, remarkably improves the levels of GSH and SOD in the brain tissue of the rat, reduces the MDA level, and has the effect of improving oxidative stress induced by cerebral ischemia reperfusion. The traditional Chinese medicine preparation can effectively relieve neurological function loss of a patient suffering from cerebral arterial thrombosis, help to recover life functions of the patient and relieve clinical symptoms of the patient, is definite and remarkable in curative effect and can be used as a new medicine for treating cerebral arterial thrombosis.

1.The name of the design product: sprayer (Qinjiao planting). 2.The use of the design product: pesticide spraying equipment for Qinjiao planting. 3.The design points of the design product: the combination of shape and color. 4.The picture or photo that best indicates the design points: perspective view 1. 5.The design for which protection is sought contains color.

The utility model discloses a traditional Chinese medicine gentiana macrophylla cultivation device which comprises a medicine soaking box, a hydraulic rod is installed at the bottom of the medicine soaking box, the output end of the hydraulic rod is connected with a filter plate, the middle of the filter plate is rotationally connected with a stirring rod, and stirring blades are installed at the upper end of the stirring rod. A first motor is installed at the bottom end of the medicine dipping box, the output end of the first motor is connected with a rotating rod, the side wall of the upper end of the medicine dipping box communicates with a material conveying pipe, and the lower end of the medicine dipping box communicates with an inner liquid discharging pipe; a cleaning box is installed on the side wall of the medicine soaking box, a water pump is installed on the outer side wall of the cleaning box, and the water outlet end of the water pump communicates with a connecting pipe. According to the cultivation device for the traditional Chinese medicine gentiana macrophylla, through rotation of the driving gear and cooperation with transmission of the meshed gear blocks, the net plate rotates, seeds can evenly fall onto the net plate, accumulation and cleaning of the seeds are avoided, clean water is sprayed to all positions of the net plate, and the seeds are efficiently cleaned.

The invention provides a traditional Chinese medicine preparation for treating liver cancer, and relates to the technical field of traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from radix fici simplicissimae, euphorbia helioscopia, herba ardisiae japonicae, pollen typhae, ginseng, radix gentianae macrophyllae, cortex eucommiae, citrus aurantium, sambucus chinensis, hypericum japonicum and fructus ziziphi jujubae. In the formula, radix fici simplicissimae and euphorbia helioscopia are used as monarch drugs, herba ardisiae japonicae, pollen typhae, ginseng and gentiana macrophylla are used as ministerial drugs, citrus aurantium, sambucus chinensis, hypericum japonicum and eucommia ulmoides are used as adjuvant drugs, Chinese dates are used as conductant drugs, and the medicines in the whole formula are reasonably matched in monarch, ministerial, adjuvant and conductant drugs, give consideration to body resistance strengthening and evil eliminating, and jointly achieve the effects of tonifying qi, strengthening body resistance, dispersing blood stasis, detoxifying, clearing heat, promoting diuresis, soothing liver and regulating qi. The traditional Chinese medicine preparation has a remarkable inhibiting effect on proliferation, migration and invasion of hepatoma carcinoma cells, can effectively reduce the tumor volume and weight of tumor-bearing mice, slows down the tumor growth speed, can effectively improve the immune organ index and immune cell factors of the tumor-bearing mice, has an immunological enhancement effect, and can be used for treating liver cancer. The traditional Chinese medicine preparation is expected to serve as a new choice of medicines for treating liver cancer.

The invention discloses an anti-tumor traditional Chinese medicine compound capable of removing three flavors. The anti-tumor traditional Chinese medicine compound is prepared from radix puerariae, radix scutellariae, rhizoma coptidis, cortex phellodendri, rhizoma atractylodis, radix angelicae sinensis, radix aucklandiae, radix pulsatillae, herba hedyotidis diffusae, rhizoma atractylodis macrocephalae and raw liquorice Compared with the original formula of compound radix puerariae decoction, the three-component-removing anti-tumor traditional Chinese medicine compound has the advantages that the three traditional Chinese medicines of gentiana macrophylla, rhizoma alismatis and betel nut which do not have the effects of clearing away heat and toxic materials and tonifying spleen and do not enter lung meridians are removed, the three-component-removing anti-tumor traditional Chinese medicine compound is obtained, and research finds that the formula still has the anti-colorectal cancer efficacy, the anti-breast cancer efficacy is increased, and the anti-tumor effect is good. Compared with the original formula of the compound radix puerariae decoction, the compound radix puerariae decoction has higher safety.

The invention discloses a traditional Chinese medicine composition for treating rheumatic bone pain and a preparation method of the traditional Chinese medicine composition, and relates to the technical field of traditional Chinese medicines. The ointment consists of traditional Chinese medicine components and auxiliary materials, wherein the traditional Chinese medicine components of the ointment are prepared from the following components: unprocessed radix aconiti, unprocessed radix aconiti kusnezoffii, scorpio, centipede, earthworm, frankincense, myrrh, notopterygium root, radix angelicae pubescentis, radix clematidis, gentiana macrophylla, lycopodium clavatum, safflower and phryma leptostachya; the decoction is prepared from the following components: eucommia ulmoides, longspur epimedium, radix rehmanniae preparata, raw astragalus membranaceus, teasel root, semen cuscutae, radix achyranthis bidentatae, radix clematidis, salvia miltiorrhiza, radix aconiti preparata, prepared kusnezoff monkshood root, angelica sinensis and liquorice. According to the invention, a treatment mode of combining external use of ointment and oral administration of decoction is innovatively adopted, aiming at the pathogenesis characteristics of rheumatism ostalgia, local symptoms are rapidly relieved through the external ointment, the internal organ function is fundamentally conditioned through the oral decoction, the treatment strategy of treating symptoms in emergency and treating root causes in slow is realized, and the clinical curative effect is remarkably improved.

The invention provides a natural herbal compound factor with a bidirectional immune skin care function and a preparation method thereof, and relates to the technical field of skin care product processing, the natural herbal compound factor comprises 1.2-3.5 parts by weight of a gentiana macrophylla extract, 0.9-2.8 parts by weight of a gentiana scabra bunge extract, 0.8-2.2 parts by weight of a swertia bimaculata extract, (a) a screen protection synergist, (b) a natural stabilizer, and (c) a solvent, the (a) is prepared from 0.6-1.8 parts by weight of stephania tetrandra extract, 1.8-4.5 parts by weight of oat extract, 0.9-2.7 parts by weight of phellinus linteus extract, 0.4-1.8 parts by weight of gardenia extract and 0.8-3.2 parts by weight of paeonia lactiflora pall extract.According to the present invention, the stirring blade assembly and the spiral separation plate with the flow guide groove are arranged, and the spiral separation plate can rotate along with the water vapor so as to achieve the stirring effect; and the stirring blade assembly is driven to synchronously rotate in the heating and purifying tank, so that foam generated by bumping of liquid in the heating and purifying tank is directly and physically eliminated, and raw material loss caused by foam overflow or loss of the extracting solution is effectively avoided.

The embodiment of the invention discloses a traditional Chinese medicine preparation for body detoxification and wind-damp expelling and a preparation method thereof. The traditional Chinese medicine preparation is prepared from the following traditional Chinese medicinal materials in parts by weight: 10 parts of cassia twig, 15 parts of divaricate saposhnikovia root, 10 parts of notopterygium root, 10 parts of schizonepeta spike, 10 parts of anisetree bark, 15 parts of long-noded pit viper, 15 parts of pawpaw, 10 parts of gentiana macrophylla, 15 parts of cortex acanthopanacis, 15 parts of obscured homalomena rhizome, 15 parts of beautiful millettia root, 10 parts of philippine flemingia root, 15 parts of parasitic loranthus, 10 parts of radix astragali preparata, 15 parts of fried bighead atractylodes rhizome, 10 parts of wolfberry, 15 parts of eucommia ulmoides, 15 parts of teasel root, 15 parts of angelica sinensis, 10 parts of prepared rehmannia root, 10 parts of white paeony root, 10 parts of poria cocos The traditional Chinese medicine composition is prepared from 10 parts of radix aucklandiae, 15 parts of rhizoma chuanxiong, 20 parts of flos carthami, 9 parts of radix achyranthis bidentatae, 10 parts of semen brassicae, 10 parts of apricot kernels, 10 parts of radix polygalae, 15 parts of rhizoma gastrodiae, 10 parts of radix rehmanniae recen and 15 parts of herba houttuyniae. According to clinical verification, the traditional Chinese medicine preparation provided by the invention is remarkable in curative effect on symptoms such as arthralgia, waist and back ache and the like, small in side effect, economical and practical, convenient to carry, and capable of meeting the medical requirements of the times and providing a new treatment choice for patients with rheumatism.

The invention discloses a medicine for treating herpes zoster. The medicine is prepared from Viola yedoensis, chrysanthemum, honeysuckle, forsythia, Rehmannia root, pyrrosia, honeysuckle vine, white peony root, gentiana macrophylla, Chinese angelica, and Ligusticum chuanxiong. The medicine has the effects of clearing the liver and purging fire, clearing heat and detoxifying, promoting dampness and unblocking the meridians, and is used to treat herpes zoster with liver and gallbladder damp-heat syndrome. The medicine is suitable for people suffering from herpes zoster with liver and gallbladder damp-heat syndrome accompanied by bitter taste in the mouth, dry throat, irritability, yellow urine, dry stool, red tongue, thin yellow or thick yellow fur, and a stringy, slippery, and rapid pulse.

The invention provides a natural plant feed additive for improving immunity and promoting growth as well as a preparation method and application thereof, and relates to the field of feed additives, the natural plant feed additive is prepared from fourteen plant raw materials including gynostemma pentaphyllum, scandent hop, gentiana macrophylla, glossy privet fruit, flatstem milkvetch seed, sargentgloryvine stem, sea-buckthorn, astragalus membranaceus, radish seed, Chinese violet, humifuse euphorbia herb, ampelopsis japonica, paulownia flower and platycodon grandiflorum. The additive has multi-dimensional biological activity of promoting growth, enhancing immunity, resisting oxidation and protecting organs, can improve the growth performance of livestock and poultry by improving the average daily gain and reducing the feed-gain ratio to optimize the feed conversion rate, and can construct a humoral immune barrier by reducing the secretion of proinflammatory factors and increasing the level of anti-inflammatory factors to improve the immunity of livestock and poultry. According to the present invention, with the application of the composition, the protein and lipid metabolism disorder can be improved, the activity of ALT, AST and ALP can be reduced so as to protect the liver and the kidney and maintain the steady state of the body, the overall health level of livestock and poultry can be improved without the dependence on chemical agents, and the reliable technical support can be provided for promoting the development of the green, safe and efficient livestock and poultry breeding mode.

This application relates to a traditional Chinese medicine composition for treating osteoarthritis and its preparation method, comprising 1-3 parts of safflower, 0.5-1.5 parts of angelica sinensis, 0.5-1.5 parts of angelica dahurica, 1-3 parts of dioscorea hypoglauca, 0.5-1.5 parts of achyranthes bidentata, 0.5-1.5 parts of asarum sieboldii, 0.5-1.5 parts of gentiana macrophylla, 0.5-1.5 parts of eucommia ulmoides, 0.5-1.5 parts of licorice, 1-3 parts of dioscorea nipponica, 1-3 parts of coix seed, 0.5-1.5 parts of processed aconite root, 0.5-1.5 parts of processed aconite tuber, and 0.5-1.5 parts of processed arisaema tuber, with each component in the indicated weight proportions. This composition, through the synergistic effect of multiple traditional Chinese medicines, possesses the effects of promoting blood circulation, removing blood stasis, dispelling wind and dampness, clearing the meridians, and relieving pain. It is suitable for treating osteoarthritis such as lumbar disc herniation, nerve compression pain, cervical / lumbar osteoarthritis, sciatica, and knee osteoarthritis. This application ensures the stable release of the drug's active ingredients through scientific formulation and weight control, thereby improving therapeutic efficacy and reducing the risk of toxic components. It has clinical application value and safety advantages.

The invention relates to the technical field of natural medicinal chemistry, and particularly discloses a fucus extract-containing composition, which comprises a fucus extract and a gentiana macrophylla extract, wherein the weight ratio of the fucus extract to the gentiana macrophylla extract is (1-10): (1-10). Researches show that the composition obtained by combining the fucus extract extracted by using acetone and the gentiana macrophylla extract extracted by using ethanol has a better sunscreen effect; the sunscreen effect of the extract is obviously higher than that of the fucus extract independently extracted by acetone and that of the gentiana macrophylla extract independently extracted by ethanol. Therefore, the composition containing the fucus extract, which is disclosed by the invention, has important application value when being used as an active ingredient for preparing a product with a sunscreen effect.

The invention discloses an external nursing cream containing white muscardine silkworm and gentiana macrophylla and a preparation method thereof, the nursing cream takes white muscardine silkworm and gentiana macrophylla as main raw materials, the main raw materials are extracted by ethanol with the concentration of 20-99%, and the ethanol can be edible wine, health care medicinal liquor or medical ethanol; and the finished product is mild for external use after being blended by a matrix, and the irritation is controllable. Auxiliary materials such as artificial musk, ground beeltle, mirabilite, myrrh and angelica sinensis can be selectively added, and the ointment is prepared by extracting, concentrating and adding an external matrix. The invention has the advantages of simple and mild formula, flexible and simple process, easily available raw materials and wide application range, and is suitable for daily external skin care.

The utility model relates to the technical field of gentiana macrophylla planting, in particular to a gentiana macrophylla seed screening and mixing device which comprises a mixing bin, a screening bin and a sand box are arranged above the mixing bin, a screening plate is arranged on the inner side of the screening bin, a vibration motor is arranged at the lower end of the screening plate, and a collecting box is arranged on the front side of the screening bin. The lower ends of the screening bin and the sand box are communicated with same electric control valves, a weighing seat is arranged on the inner side of the mixing bin, a moving frame is arranged at the upper end of the weighing seat, a water tank is arranged on the front side of the upper end of the mixing bin, and a sprayer is arranged at the lower end of the water tank; screened seeds and fine sand respectively fall on the two weighing seats to be weighed by controlling the electric control valve to be opened, and after the seeds and the fine sand reach proper weight, the electric control valve is controlled to be closed, and then the electric push rod is controlled to work to drive the moving frame to push forwards, so that the seeds and the fine sand at the upper ends of the weighing seats are pushed out by the moving frame and fall into the bottom of the mixing bin to be mixed; the quantitative mixing of the seeds and the fine sand is realized.

The invention provides a tendon-relaxing and blood-activating composition, a tendon-relaxing and blood-activating extract, a preparation and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The composition for relaxing the muscles and stimulating the blood circulation comprises gentiana macrophylla, speranskia tuberculata, cassia twig, eucommia ulmoides, rhizoma atractylodis, radix aconiti, myrrh, salvia miltiorrhiza, divaricate saposhnikovia root, the root of kudzu vine, safflower carthamus, the root of bidentate achyranthes, notopterygium root, rhizoma drynariae, fermented rheum officinale and fermented hiraute shiny bugleweed herb. The pharmaceutical composition can effectively relieve, treat and prevent joint diseases, and is good in stability and convenient to store for a long time.

This invention relates to the field of traditional Chinese medicine (TCM) technology, specifically to a TCM composition for treating rheumatoid arthritis and its application. The TCM composition comprises the following raw materials: mulberry twigs, Gentiana macrophylla, Phellodendron chinense, earthworm, stir-fried Arctium lappa, Achyranthes bidentata, stir-fried Bombyx mori, Lonicera japonica, and Spatholobus suberectus. This TCM composition can reduce arthritis scores and paw volume in rats with rheumatoid arthritis, reduce the spleen coefficient in rats with rheumatoid arthritis, significantly reduce TNF-α, IL-6, and IL-1β in rat serum, improve joint inflammation, and has no toxic side effects. This indicates that the TCM composition for treating rheumatoid arthritis in this application can alleviate symptoms in patients with rheumatoid arthritis, exert its anti-inflammatory and analgesic effects, and thus treat rheumatoid arthritis.

The invention discloses application of a gentiana macrophylla extract in preparation of a vibrio harveyi inhibitor. The gentiana macrophylla extract is obtained by extracting a gentiana macrophylla sample with an organic solvent. The gentiana macrophylla extract prepared by the invention can specifically inhibit vibrio harveyi, does not generate drug resistance, and has the characteristics of high efficiency, safety and no toxic or side effect. The invention also provides an aquaculture feed prepared from the gentiana macrophylla extract, and when aquatic animals are fed with the aquaculture feed disclosed by the invention, the vibrio harveyi resistance of the aquatic animals can be improved, and healthy, stable and sustainable development of the aquaculture industry is facilitated.

The invention discloses a benzopyran enantiomer and its preparation method and application. The present invention extracts and separates a pair of benzopyran enantiomers from the rhizome of Gentiana macrophylla, and evaluates the hepatoprotective activity of Gentiana macrophylla benzopyran by detecting the inhibitory effect of the benzopyran enantiomer on acetaminophen-induced human hepatocyte (L-O2) damage in vitro. It was found that the benzopyran enantiomer has good hepatoprotective activity. The preparation method of the benzopyran enantiomer provided by the present invention is simple to operate and low in cost, and the obtained benzopyran has high purity, a clear structure, and a variety of potential application values, which lays the foundation for the development of the medicinal value of Gentiana macrophylla benzopyran.

The invention discloses a fragrant bath tablet which comprises the following components in parts by mass: 5-100 parts of geranium wilfordii, 1-20 parts of ephedra or elsholtzia, 2-40 parts of juniperus formosana, 1-20 parts of rhodiola rosea, 5-100 parts of folium artemisiae argyi, 5 parts of safflower, 1-20 parts of gentiana macrophylla and 1-20 parts of divaricate saposhnikovia root. The components are processed, tableted and molded. The fragrant bath tablet provided by the invention has the advantages of clearing and activating the channels and collaterals, expelling wind, fending off cold and removing dampness, also has the advantages of inducing resuscitation, detoxifying and nourishing blood vessels, is suitable for people with numbness of limbs, weakness and weakness of hands and feet, painful whole body, rubella and the like, and is also suitable for people with joint disadvantage, limb pain, cold limbs and cold head; and the product also has a good fragrant smell.

The invention discloses a soothing and repairing skin care composition as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The skin care composition is prepared from the following components in parts by mass: 3 to 7 parts of herba centellae extract, 0.5 to 1 part of radix scutellariae extract, 2 to 4 parts of rhizoma polygoni cuspidati extract, 1 to 3 parts of radix gentianae extract and 15 to 20 parts of rhizoma atractylodis macrocephalae extract. Wherein the rhizoma atractylodis macrocephalae root extract is prepared by adopting a compound fermentation process of rhodotorula glutinis, lactobacillus brewer and lactobacillus paracasei, and active ingredients are richer. Through the synergistic effect of multiple components, the composition can significantly inhibit secretion of inflammatory factors IL-6 and activity of hyaluronidase and promote HaCaT cell migration, has excellent soothing, anti-inflammatory and repairing effects, and can effectively improve the problems of skin sensitivity, dryness and barrier injury.

This invention discloses a soothing and repairing Gentiana macrophylla extract composition, its preparation method, and its application, specifically belonging to the technical field of daily necessities raw material preparation. The Gentiana macrophylla extract composition is obtained by solvent extraction after solid-state fermentation of Gentiana macrophylla by Aspergillus oryzae, Leuconostoc mesenteroides, and Saccharomyces cerevisiae. The Gentiana macrophylla extract composition provided by this invention has a high oleanolic acid content, proving that Aspergillus oryzae, Leuconostoc mesenteroides, and Saccharomyces cerevisiae can effectively enrich the active ingredients in Gentiana macrophylla, and at the same time, they exhibit a certain synergistic effect on the enrichment of active ingredients during the fermentation process. The Gentiana macrophylla extract composition provided by this invention can effectively inhibit the release of inflammatory factors and promote skin repair.

This invention provides a traditional Chinese medicine preparation for treating liver cancer, belonging to the field of traditional Chinese medicine pharmaceutical technology. The preparation is made from five-finger peach, *Euphorbia helioscopia*, *Lysimachia christinae*, *Typha orientalis*, *Gentiana macrophylla*, *Eucommia ulmoides*, *Bitter orange blossom*, *Gynostemma pentaphyllum*, *Gynostemma pentaphyllum*, and jujube. Five-finger peach and *Euphorbia helioscopia* are the principal herbs; *Lysimachia christinae*, *Typha orientalis*, *Gentiana macrophylla*, and *Gentiana macrophylla* are the assistant herbs; *Bitter orange blossom*, *Gynostemma pentaphyllum*, *Gynostemma pentaphyllum*, and *Eucommia ulmoides* are the adjuvant herbs; and jujube is the guiding herb. The combination of these herbs is rational, balancing the strengthening of the body's resistance with the elimination of pathogenic factors, achieving the effects of tonifying qi and strengthening the body's resistance, resolving blood stasis and detoxifying, clearing heat and promoting diuresis, and soothing the liver and regulating qi. This traditional Chinese medicine preparation significantly inhibits the proliferation, migration, and invasion of liver cancer cells, effectively reduces tumor volume and weight in tumor-bearing mice, slows tumor growth, and effectively improves immune organ indices and immune cytokines in tumor-bearing mice, exhibiting an immune-enhancing effect. This traditional Chinese medicine preparation shows promise as a new option for treating liver cancer.

The application provides a traditional Chinese medicine preparation for ischemic cerebral stroke, and belongs to the technical field of traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from Gentiana macrophylla Pall, Saposhnikovia divaricata, Morus alba, Scrophularia ningpoensis, red ocher, Fritillaria delavayi Franch, bamboo juice, Prunella vulgaris, Hericium, and Melia toosendan. The traditional Chinese medicine preparation has the functions of calming liver and hiding yang, calming wind and stopping convulsion, and removing phlegm and opening orifices. The traditional Chinese medicine preparation has a significant improvement effect on the nerve function of a cerebral ischemia-reperfusion injury model rat, can effectively reduce the brain tissue water content and cerebral infarction volume of the rat, significantly increase the GSH and SOD levels in the brain tissue of the rat, and reduce the MDA level, and has an effect of improving the oxidative stress induced by cerebral ischemia-reperfusion. The traditional Chinese medicine preparation can effectively relieve the nerve function loss of a patient with ischemic cerebral stroke, help restore the life function of the patient, and reduce the clinical symptoms of the patient, and has a definite and significant curative effect, and can be used as a new drug for treating ischemic cerebral stroke.