46 results about "Gentiana macrophylla" patented technology

The invention relates to the technical field of cosmetics, and particularly discloses a composition with long-acting moisturizing and repairing effects and application thereof. The composition is prepared from radix gentianae macrophyllae extract, mussel extract, leontopodium alpinum flower / leaf extract and rhizoma anemarrhenae root extract according to the mass ratio of 1: (0.5 to 1.5): (0.7 to 0.9): (0.1 to 0.3). According to the composition, through a multi-path synergistic effect, the gentiana macrophylla extract reduces water loss, the mussel extract constructs a dermis water storage network, the leontopodium alpinum extract enhances water locking and barrier repairing, and the rhizoma anemarrhenae root extract improves the water content of a cuticle. Experiments show that the gentiana macrophylla extract, the mussel extract, the leontopodium alpinum flower / leaf extract and the rhizoma anemarrhenae root extract are combined according to the mass ratio of 1: 1: 0.8: 0.2 for use, and the 8-hour moisturizing rate of the composition is as high as 79.69%. The composition can be added into cosmetics such as essence, emulsion and the like, and has high moisture retention, barrier repairing power and safety.

The invention provides a traditional Chinese medicine composition for treating rheumatic arthritis, a preparation and application, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following medicinal raw materials: 12-18 parts of sailong bone, 6-12 parts of radix aconiti lateralis preparata, 3-9 parts of radix aconiti preparata, 9-15 parts of cassia twig, 1-4 parts of asarum, 9-15 parts of radix clematidis, 20-40 parts of astragalus membranaceus, 3-9 parts of scorpio, 9-15 parts of earthworm, 9-15 parts of caulis sinomenii, 12-18 parts of bighead atractylodes rhizome, 12-18 parts of poria cocos, 9-15 parts of gentiana macrophylla, 12-18 parts of angelica sinensis, 20-40 parts of caulis spatholobi, 9-15 parts of rhizoma drynariae, 12-18 parts of radix paeoniae alba, 3-9 parts of honey-fried licorice root and 6-12 parts of rhizoma zingiberis. According to the traditional Chinese medicine composition for treating rheumatic arthritis, the medicine raw material composition of the traditional Chinese medicine composition for treating rheumatic arthritis is reasonably designed, four pathological links of cold, dampness, stasis and deficiency of rheumatic arthritis are covered through precise compatibility of monarch, minister, assistant and guide, and the traditional Chinese medicine composition has triple curative effects of anti-inflammatory analgesia, immunoregulation and bone protection.

1.The name of the design product: sprayer (Qinjiao planting). 2.The use of the design product: pesticide spraying equipment for Qinjiao planting. 3.The design points of the design product: the combination of shape and color. 4.The picture or photo that best indicates the design points: perspective view 1. 5.The design for which protection is sought contains color.

The utility model discloses a traditional Chinese medicine gentiana macrophylla cultivation device which comprises a medicine soaking box, a hydraulic rod is installed at the bottom of the medicine soaking box, the output end of the hydraulic rod is connected with a filter plate, the middle of the filter plate is rotationally connected with a stirring rod, and stirring blades are installed at the upper end of the stirring rod. A first motor is installed at the bottom end of the medicine dipping box, the output end of the first motor is connected with a rotating rod, the side wall of the upper end of the medicine dipping box communicates with a material conveying pipe, and the lower end of the medicine dipping box communicates with an inner liquid discharging pipe; a cleaning box is installed on the side wall of the medicine soaking box, a water pump is installed on the outer side wall of the cleaning box, and the water outlet end of the water pump communicates with a connecting pipe. According to the cultivation device for the traditional Chinese medicine gentiana macrophylla, through rotation of the driving gear and cooperation with transmission of the meshed gear blocks, the net plate rotates, seeds can evenly fall onto the net plate, accumulation and cleaning of the seeds are avoided, clean water is sprayed to all positions of the net plate, and the seeds are efficiently cleaned.

The invention provides a traditional Chinese medicine preparation for treating liver cancer, and relates to the technical field of traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from radix fici simplicissimae, euphorbia helioscopia, herba ardisiae japonicae, pollen typhae, ginseng, radix gentianae macrophyllae, cortex eucommiae, citrus aurantium, sambucus chinensis, hypericum japonicum and fructus ziziphi jujubae. In the formula, radix fici simplicissimae and euphorbia helioscopia are used as monarch drugs, herba ardisiae japonicae, pollen typhae, ginseng and gentiana macrophylla are used as ministerial drugs, citrus aurantium, sambucus chinensis, hypericum japonicum and eucommia ulmoides are used as adjuvant drugs, Chinese dates are used as conductant drugs, and the medicines in the whole formula are reasonably matched in monarch, ministerial, adjuvant and conductant drugs, give consideration to body resistance strengthening and evil eliminating, and jointly achieve the effects of tonifying qi, strengthening body resistance, dispersing blood stasis, detoxifying, clearing heat, promoting diuresis, soothing liver and regulating qi. The traditional Chinese medicine preparation has a remarkable inhibiting effect on proliferation, migration and invasion of hepatoma carcinoma cells, can effectively reduce the tumor volume and weight of tumor-bearing mice, slows down the tumor growth speed, can effectively improve the immune organ index and immune cell factors of the tumor-bearing mice, has an immunological enhancement effect, and can be used for treating liver cancer. The traditional Chinese medicine preparation is expected to serve as a new choice of medicines for treating liver cancer.

The invention discloses an anti-tumor traditional Chinese medicine compound capable of removing three flavors. The anti-tumor traditional Chinese medicine compound is prepared from radix puerariae, radix scutellariae, rhizoma coptidis, cortex phellodendri, rhizoma atractylodis, radix angelicae sinensis, radix aucklandiae, radix pulsatillae, herba hedyotidis diffusae, rhizoma atractylodis macrocephalae and raw liquorice Compared with the original formula of compound radix puerariae decoction, the three-component-removing anti-tumor traditional Chinese medicine compound has the advantages that the three traditional Chinese medicines of gentiana macrophylla, rhizoma alismatis and betel nut which do not have the effects of clearing away heat and toxic materials and tonifying spleen and do not enter lung meridians are removed, the three-component-removing anti-tumor traditional Chinese medicine compound is obtained, and research finds that the formula still has the anti-colorectal cancer efficacy, the anti-breast cancer efficacy is increased, and the anti-tumor effect is good. Compared with the original formula of the compound radix puerariae decoction, the compound radix puerariae decoction has higher safety.

The invention discloses a traditional Chinese medicine composition for treating rheumatic bone pain and a preparation method of the traditional Chinese medicine composition, and relates to the technical field of traditional Chinese medicines. The ointment consists of traditional Chinese medicine components and auxiliary materials, wherein the traditional Chinese medicine components of the ointment are prepared from the following components: unprocessed radix aconiti, unprocessed radix aconiti kusnezoffii, scorpio, centipede, earthworm, frankincense, myrrh, notopterygium root, radix angelicae pubescentis, radix clematidis, gentiana macrophylla, lycopodium clavatum, safflower and phryma leptostachya; the decoction is prepared from the following components: eucommia ulmoides, longspur epimedium, radix rehmanniae preparata, raw astragalus membranaceus, teasel root, semen cuscutae, radix achyranthis bidentatae, radix clematidis, salvia miltiorrhiza, radix aconiti preparata, prepared kusnezoff monkshood root, angelica sinensis and liquorice. According to the invention, a treatment mode of combining external use of ointment and oral administration of decoction is innovatively adopted, aiming at the pathogenesis characteristics of rheumatism ostalgia, local symptoms are rapidly relieved through the external ointment, the internal organ function is fundamentally conditioned through the oral decoction, the treatment strategy of treating symptoms in emergency and treating root causes in slow is realized, and the clinical curative effect is remarkably improved.

The invention provides a natural herbal compound factor with a bidirectional immune skin care function and a preparation method thereof, and relates to the technical field of skin care product processing, the natural herbal compound factor comprises 1.2-3.5 parts by weight of a gentiana macrophylla extract, 0.9-2.8 parts by weight of a gentiana scabra bunge extract, 0.8-2.2 parts by weight of a swertia bimaculata extract, (a) a screen protection synergist, (b) a natural stabilizer, and (c) a solvent, the (a) is prepared from 0.6-1.8 parts by weight of stephania tetrandra extract, 1.8-4.5 parts by weight of oat extract, 0.9-2.7 parts by weight of phellinus linteus extract, 0.4-1.8 parts by weight of gardenia extract and 0.8-3.2 parts by weight of paeonia lactiflora pall extract.According to the present invention, the stirring blade assembly and the spiral separation plate with the flow guide groove are arranged, and the spiral separation plate can rotate along with the water vapor so as to achieve the stirring effect; and the stirring blade assembly is driven to synchronously rotate in the heating and purifying tank, so that foam generated by bumping of liquid in the heating and purifying tank is directly and physically eliminated, and raw material loss caused by foam overflow or loss of the extracting solution is effectively avoided.

The invention provides a natural plant feed additive for improving immunity and promoting growth as well as a preparation method and application thereof, and relates to the field of feed additives, the natural plant feed additive is prepared from fourteen plant raw materials including gynostemma pentaphyllum, scandent hop, gentiana macrophylla, glossy privet fruit, flatstem milkvetch seed, sargentgloryvine stem, sea-buckthorn, astragalus membranaceus, radish seed, Chinese violet, humifuse euphorbia herb, ampelopsis japonica, paulownia flower and platycodon grandiflorum. The additive has multi-dimensional biological activity of promoting growth, enhancing immunity, resisting oxidation and protecting organs, can improve the growth performance of livestock and poultry by improving the average daily gain and reducing the feed-gain ratio to optimize the feed conversion rate, and can construct a humoral immune barrier by reducing the secretion of proinflammatory factors and increasing the level of anti-inflammatory factors to improve the immunity of livestock and poultry. According to the present invention, with the application of the composition, the protein and lipid metabolism disorder can be improved, the activity of ALT, AST and ALP can be reduced so as to protect the liver and the kidney and maintain the steady state of the body, the overall health level of livestock and poultry can be improved without the dependence on chemical agents, and the reliable technical support can be provided for promoting the development of the green, safe and efficient livestock and poultry breeding mode.

This application relates to a traditional Chinese medicine composition for treating osteoarthritis and its preparation method, comprising 1-3 parts of safflower, 0.5-1.5 parts of angelica sinensis, 0.5-1.5 parts of angelica dahurica, 1-3 parts of dioscorea hypoglauca, 0.5-1.5 parts of achyranthes bidentata, 0.5-1.5 parts of asarum sieboldii, 0.5-1.5 parts of gentiana macrophylla, 0.5-1.5 parts of eucommia ulmoides, 0.5-1.5 parts of licorice, 1-3 parts of dioscorea nipponica, 1-3 parts of coix seed, 0.5-1.5 parts of processed aconite root, 0.5-1.5 parts of processed aconite tuber, and 0.5-1.5 parts of processed arisaema tuber, with each component in the indicated weight proportions. This composition, through the synergistic effect of multiple traditional Chinese medicines, possesses the effects of promoting blood circulation, removing blood stasis, dispelling wind and dampness, clearing the meridians, and relieving pain. It is suitable for treating osteoarthritis such as lumbar disc herniation, nerve compression pain, cervical / lumbar osteoarthritis, sciatica, and knee osteoarthritis. This application ensures the stable release of the drug's active ingredients through scientific formulation and weight control, thereby improving therapeutic efficacy and reducing the risk of toxic components. It has clinical application value and safety advantages.

The invention discloses an external nursing cream containing white muscardine silkworm and gentiana macrophylla and a preparation method thereof, the nursing cream takes white muscardine silkworm and gentiana macrophylla as main raw materials, the main raw materials are extracted by ethanol with the concentration of 20-99%, and the ethanol can be edible wine, health care medicinal liquor or medical ethanol; and the finished product is mild for external use after being blended by a matrix, and the irritation is controllable. Auxiliary materials such as artificial musk, ground beeltle, mirabilite, myrrh and angelica sinensis can be selectively added, and the ointment is prepared by extracting, concentrating and adding an external matrix. The invention has the advantages of simple and mild formula, flexible and simple process, easily available raw materials and wide application range, and is suitable for daily external skin care.

The invention provides a tendon-relaxing and blood-activating composition, a tendon-relaxing and blood-activating extract, a preparation and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The composition for relaxing the muscles and stimulating the blood circulation comprises gentiana macrophylla, speranskia tuberculata, cassia twig, eucommia ulmoides, rhizoma atractylodis, radix aconiti, myrrh, salvia miltiorrhiza, divaricate saposhnikovia root, the root of kudzu vine, safflower carthamus, the root of bidentate achyranthes, notopterygium root, rhizoma drynariae, fermented rheum officinale and fermented hiraute shiny bugleweed herb. The pharmaceutical composition can effectively relieve, treat and prevent joint diseases, and is good in stability and convenient to store for a long time.

This invention relates to the field of traditional Chinese medicine (TCM) technology, specifically to a TCM composition for treating rheumatoid arthritis and its application. The TCM composition comprises the following raw materials: mulberry twigs, Gentiana macrophylla, Phellodendron chinense, earthworm, stir-fried Arctium lappa, Achyranthes bidentata, stir-fried Bombyx mori, Lonicera japonica, and Spatholobus suberectus. This TCM composition can reduce arthritis scores and paw volume in rats with rheumatoid arthritis, reduce the spleen coefficient in rats with rheumatoid arthritis, significantly reduce TNF-α, IL-6, and IL-1β in rat serum, improve joint inflammation, and has no toxic side effects. This indicates that the TCM composition for treating rheumatoid arthritis in this application can alleviate symptoms in patients with rheumatoid arthritis, exert its anti-inflammatory and analgesic effects, and thus treat rheumatoid arthritis.

The invention discloses application of a gentiana macrophylla extract in preparation of a vibrio harveyi inhibitor. The gentiana macrophylla extract is obtained by extracting a gentiana macrophylla sample with an organic solvent. The gentiana macrophylla extract prepared by the invention can specifically inhibit vibrio harveyi, does not generate drug resistance, and has the characteristics of high efficiency, safety and no toxic or side effect. The invention also provides an aquaculture feed prepared from the gentiana macrophylla extract, and when aquatic animals are fed with the aquaculture feed disclosed by the invention, the vibrio harveyi resistance of the aquatic animals can be improved, and healthy, stable and sustainable development of the aquaculture industry is facilitated.

The invention discloses a soothing and repairing skin care composition as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The skin care composition is prepared from the following components in parts by mass: 3 to 7 parts of herba centellae extract, 0.5 to 1 part of radix scutellariae extract, 2 to 4 parts of rhizoma polygoni cuspidati extract, 1 to 3 parts of radix gentianae extract and 15 to 20 parts of rhizoma atractylodis macrocephalae extract. Wherein the rhizoma atractylodis macrocephalae root extract is prepared by adopting a compound fermentation process of rhodotorula glutinis, lactobacillus brewer and lactobacillus paracasei, and active ingredients are richer. Through the synergistic effect of multiple components, the composition can significantly inhibit secretion of inflammatory factors IL-6 and activity of hyaluronidase and promote HaCaT cell migration, has excellent soothing, anti-inflammatory and repairing effects, and can effectively improve the problems of skin sensitivity, dryness and barrier injury.

This invention discloses a soothing and repairing Gentiana macrophylla extract composition, its preparation method, and its application, specifically belonging to the technical field of daily necessities raw material preparation. The Gentiana macrophylla extract composition is obtained by solvent extraction after solid-state fermentation of Gentiana macrophylla by Aspergillus oryzae, Leuconostoc mesenteroides, and Saccharomyces cerevisiae. The Gentiana macrophylla extract composition provided by this invention has a high oleanolic acid content, proving that Aspergillus oryzae, Leuconostoc mesenteroides, and Saccharomyces cerevisiae can effectively enrich the active ingredients in Gentiana macrophylla, and at the same time, they exhibit a certain synergistic effect on the enrichment of active ingredients during the fermentation process. The Gentiana macrophylla extract composition provided by this invention can effectively inhibit the release of inflammatory factors and promote skin repair.

This invention provides a traditional Chinese medicine preparation for treating liver cancer, belonging to the field of traditional Chinese medicine pharmaceutical technology. The preparation is made from five-finger peach, *Euphorbia helioscopia*, *Lysimachia christinae*, *Typha orientalis*, *Gentiana macrophylla*, *Eucommia ulmoides*, *Bitter orange blossom*, *Gynostemma pentaphyllum*, *Gynostemma pentaphyllum*, and jujube. Five-finger peach and *Euphorbia helioscopia* are the principal herbs; *Lysimachia christinae*, *Typha orientalis*, *Gentiana macrophylla*, and *Gentiana macrophylla* are the assistant herbs; *Bitter orange blossom*, *Gynostemma pentaphyllum*, *Gynostemma pentaphyllum*, and *Eucommia ulmoides* are the adjuvant herbs; and jujube is the guiding herb. The combination of these herbs is rational, balancing the strengthening of the body's resistance with the elimination of pathogenic factors, achieving the effects of tonifying qi and strengthening the body's resistance, resolving blood stasis and detoxifying, clearing heat and promoting diuresis, and soothing the liver and regulating qi. This traditional Chinese medicine preparation significantly inhibits the proliferation, migration, and invasion of liver cancer cells, effectively reduces tumor volume and weight in tumor-bearing mice, slows tumor growth, and effectively improves immune organ indices and immune cytokines in tumor-bearing mice, exhibiting an immune-enhancing effect. This traditional Chinese medicine preparation shows promise as a new option for treating liver cancer.

The application provides a traditional Chinese medicine preparation for ischemic cerebral stroke, and belongs to the technical field of traditional Chinese medicine preparation. The traditional Chinese medicine preparation is prepared from Gentiana macrophylla Pall, Saposhnikovia divaricata, Morus alba, Scrophularia ningpoensis, red ocher, Fritillaria delavayi Franch, bamboo juice, Prunella vulgaris, Hericium, and Melia toosendan. The traditional Chinese medicine preparation has the functions of calming liver and hiding yang, calming wind and stopping convulsion, and removing phlegm and opening orifices. The traditional Chinese medicine preparation has a significant improvement effect on the nerve function of a cerebral ischemia-reperfusion injury model rat, can effectively reduce the brain tissue water content and cerebral infarction volume of the rat, significantly increase the GSH and SOD levels in the brain tissue of the rat, and reduce the MDA level, and has an effect of improving the oxidative stress induced by cerebral ischemia-reperfusion. The traditional Chinese medicine preparation can effectively relieve the nerve function loss of a patient with ischemic cerebral stroke, help restore the life function of the patient, and reduce the clinical symptoms of the patient, and has a definite and significant curative effect, and can be used as a new drug for treating ischemic cerebral stroke.

The invention belongs to the technical field of recombinant proteins, and particularly relates to a gene for coding a split-ring loganin synthase, the split-ring loganin synthase, a recombinant plasmid, a recombinant bacterium and an application of the split-ring loganin synthase in catalyzing loganin acid to generate a split-ring iridoid compound, wherein the gene is cloned and separated from a gene in gentiana macrophylla pall. The sequence of the gene for coding the split-ring loganin synthase is as shown in SEQ ID NO.01, and the amino acid sequence of the split-ring loganin synthase is as shown in SEQ ID NO.02. The recombinant plasmid contains a sequence shown in SEQ ID NO. 01. The recombinant bacteria comprise recombinant yeast WAT11 or recombinant agrobacterium GV3101 and the like containing recombinant plasmids. The ring-splitting loganin synthase produced and expressed by the recombinant yeast WAT11 can be used for catalyzing loganin acid to generate sweroside, gentiopicroside or ring-splitting loganin acid. The split-ring loganin synthase produced and expressed by the recombinant agrobacterium GV3101 catalyzes loganin acid in tobacco leaves to produce gentiopicroside.

The invention discloses a radix angelicae pubescentis and parasite particle and a related substance detection method thereof, and belongs to the field of drug detection, the related substances in the radix angelicae pubescentis and parasite particle comprise radix angelicae pubescentis, angelica sinensis, ligusticum wallichii, radix paeoniae alba, liquorice, radix saposhnikoviae and gentiana macrophylla, the quality of the radix angelicae pubescentis and parasite particle is ensured to meet specified requirements, and a guarantee is provided for drug quality. The radix angelicae pubescentis and parasitic particle can play a pharmacodynamic role, and the treatment effect is better due to the combination effect of effective medicine components.

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine black plaster for treating knee osteoarthritis (KOA). Specifically, the invention provides a traditional Chinese medicine composition for treating arthritis, which is characterized by comprising the following components in parts by weight based on the total mass of the traditional Chinese medicine composition: 14-18 parts of raw astragalus membranaceus, 8-12 parts of lycopodium clavatum, 8-12 parts of garden balsam stem, 8-12 parts of safflower, 14-18 parts of red paeony root, 8-12 parts of ligusticum wallichii and 8-12 parts of wine-processed angelica sinensis. The medicine is prepared from the following raw materials in parts by weight: 8-12 parts of Chinese polyphaga, 6-10 parts of rhizoma drynariae, 8-12 parts of frankincense, 8-12 parts of myrrh, 8-12 parts of native copper, 4-8 parts of camphor, 4-8 parts of borneol, and 2-4 parts of each of radix aconiti lateralis preparata, gentiana macrophylla, fructus cnidii, clove, dragon's blood, radix achyranthis bidentatae, cortex acanthopanacis, rhizoma acori graminei, rhizoma atractylodis, radix aucklandiae, cinnamon, ginger processed pinellia, dendrobe, yam rhizome and peach kernel.

The utility model discloses a gentiana macrophylla seed screening device which comprises a rack, a screening main body is arranged on the rack, fine sand is arranged in the screening main body, a first rotating assembly used for rotating the screening main body is arranged between the screening main body and the rack, an outer filtering main body is arranged in the screening main body, and a second rotating assembly used for rotating the screening main body is arranged in the outer filtering main body. And the two ends of the outer filtering main body penetrate out of the outer side of the screening main body. According to the gentiana macrophylla seed screening device, gentiana macrophylla seeds can be screened, large-size impurities are separated and discharged by the inner filtering main body, small-size impurities are separated by the outer filtering main body and can be left in the screening main body, and the screened gentiana macrophylla seeds are discharged through the second discharging opening, so that the efficient screening working efficiency of the device on the seeds is guaranteed; and meanwhile, fine sand exists in the screening body, the seeds make full contact and friction with the fine sand in the screening process, the surfaces of the seeds can be fully damaged, seed screening and seed skin abrasion are synchronously completed, the seed planting pretreatment work efficiency is effectively improved, and the use value of the device is highlighted.

The invention relates to the technical field of daily chemicals, and particularly discloses an efficient soothing and anti-allergy plant composite extract as well as a preparation method and application thereof. The invention discloses an efficient soothing and anti-allergy plant composite extract. The extract is prepared from the following raw material components in parts by weight: 11-30 parts of radix gentianae macrophyllae, 57-65 parts of swertia mileensis, 5-10 parts of swertia, 3-5 parts of liquorice and 2-4 parts of centella asiatica. A preparation method of an efficient soothing and anti-allergy plant composite extract comprises the following steps: rapidly rinsing crushed gentiana macrophylla and swertia mileensis with a citric acid aqueous solution with a pH value of 4-5 at room temperature for 2-3 times to obtain a water washing raw material; performing external circulation extraction on the washed raw material, the swertia, the liquorice and the centella asiatica to obtain an extracting solution; performing flocculation; filtering is performed; performing ultrafiltration; performing nanofiltration; the preparation method comprises the following steps: adding propylene glycol or butanediol and a natural chelating agent into the nanofiltration concentrated solution to obtain the efficient soothing anti-allergy plant composite extract.

The invention discloses a plant composition with anti-inflammatory and soothing effects as well as a preparation method and application thereof, the plant composition comprises a Chinese herbaceous peony root extract, a polygonatum cyrtonema rhizome / root extract and a gentiana macrophylla extract, and the components are uniformly mixed during preparation; the Chinese herbaceous peony root extract, the polygonatum cyrtonema rhizome / root extract and the gentiana macrophylla extract are compounded, an unexpected excellent effect is obtained, particularly, the antioxidant relieving and lasting effects are obviously improved, meanwhile, the irritation is low, and the composition is suitable for wider skin types and can effectively cope with various inflammation inducements; after the three components are compounded, a channel from the early stage to the late stage of inflammatory response is covered, the limitation of a single target spot is broken through, and the composition has the effects of resisting aging and repairing after-sun injury and can be used for preparing various cosmetics.

The invention provides a plant extraction compound factor with anti-inflammatory and anti-allergy functions and a preparation method thereof, and relates to the technical field of skin care product processing, the plant extraction compound factor is prepared from the following raw materials by weight: 8-10 parts of gentiana macrophylla, 5-7 parts of swertia mileensis, 4-6 parts of stephania tetrandra, 6-8 parts of phellinus igniarius, and 7-9 parts of peony. The plant extraction compound factor is prepared from the following raw materials in parts by weight: 5-7 parts of eucommia ulmoides, 4-6 parts of magnolia sieboldii, 6-8 parts of andrographis paniculata and 3-5 parts of polygala tenuifolia, and the plant extraction compound factor is prepared from the following raw materials in parts by weight: 8-10 parts of centella asiatica, 3-5 parts of bamboo shavings, 5-7 parts of fructus forsythiae and 4-6 parts of amur corktree. The plant extraction compound factor is prepared from the following raw materials in parts by weight: 3-5 parts of coreopsis tinctoria, 7-9 parts of liquorice, 2-4 parts of pelargonium graveolens and 3-5 parts of broom leaf Australian tea.

The invention relates to an anti-allergy composition containing leontopodium alpinum and gentiana macrophylla, and belongs to the technical field of cosmetics. The anti-allergy composition containing leontopodium alpinum and gentiana macrophylla, disclosed by the invention, is prepared from the following components in parts by mass: 1 to 3 parts of gentiana macrophylla extract, 1 to 3 parts of leontopodium alpinum extract, 0.1 to 1 part of ormosia henryi bark extract and 2 to 4 parts of wood apple extract. The composition prepared from the components in parts by mass has a remarkable anti-allergy effect.

The invention relates to a traditional Chinese medicine composition and a traditional Chinese medicine preparation for hip joint osteoarthritis of companion animals. The traditional Chinese medicine composition for the hip joint osteoarthritis of the companion animals comprises the following traditional Chinese medicine components in parts by weight: 1-5 parts of notopterygium root, 1-5 parts of radix angelicae pubescentis, 1-5 parts of radix achyranthis bidentatae, 1-5 parts of peach kernel, 1-5 parts of safflower, 1-5 parts of radix stephaniae tetrandrae, 1-5 parts of gentiana macrophylla and 1-10 parts The traditional Chinese medicine composition and the traditional Chinese medicine preparation can be used for effectively and safely treating hip joint osteoarthritis of companion animals such as dogs and cats, and particularly, the effect is better when the traditional Chinese medicine composition and the traditional Chinese medicine preparation are matched with a traditional Chinese medicine iontophoresis method.

The invention relates to an external traditional Chinese medicine ointment composition for treating lumbar disc herniation, which can effectively solve the problems of slow effect and limited effect of the existing medicine for treating lumbar disc herniation. The traditional Chinese medicine is prepared from frankincense, asarum, borneol, alangium platanifolium, radix aconiti kusnezoffii, herba chloranthi serrati, radix aconiti, short-pedicel aconite root, herba taxilli, kadsura longepedunculata, radix angelicae pubescentis, garden balsam stem, lycopodium clavatum, radix rehmanniae, prepared rehmannia root, radix dipsaci, safflower, rhizoma smilacis glabrae, cuttlebone, angelica sinensis, sappan wood, paris polyphylla, sea horse, semen momordicae, semen strychni, anisodus acutangulus, astragalus membranaceus, pseudo-ginseng, rhizoma drynariae, herba epimedii, obscured homalomena rhizome, eucommia ulmoides, kadsura pepper stem, acanthopanax, schizophragma integrifolium, the black plaster is prepared from bighead atractylodes rhizome, cinnamon, rhizoma atractylodis, codonopsis pilosula, poria cocos, gentiana macrophylla, hairyvein agrimony, radix sophorae flavescentis, fructus kochiae, common carpesium fruit, coptis chinensis, scutellaria baicalensis, golden cypress, rheum officinale, honeysuckle, radix clematidis, radix paeoniae rubra, long-noded pit viper, ground beetle, liquidambar formosana hance and bulbus fritillariae cirrhosae according to a conventional black method. The traditional Chinese medicine composition has the effects of activating blood, relieving pain, removing stasis and diminishing swelling.

The application discloses application of quercetrin in preparation of a medicine for enhancing the effect of gemcitabine on pancreatic cancer, and belongs to the technical field of medicines. Quercetrin can be extracted from Gentiana macrophylla Pall or synthesized, and the IC 50 of the quercetrin on the proliferation of multiple pancreatic cancer cell lines is 21.8-25.3 μM in vitro, the tumor inhibition rate is more than 50% under the condition of 15 mg / kg / day in vivo, and no obvious systemic toxicity is observed. The study shows that the quercetrin has a significant synergistic effect when combined with gemcitabine, the IC 50 of gemcitabine can be reduced by several times to more than ten times, the tumor inhibition effect of combined administration is better than that of single drug, and no additional toxicity is increased. The mechanism is that the quercetrin regulates cycle-related proteins to induce G0 / G1 phase arrest of pancreatic cancer cells, potential target points include PARP1 and MDM2, and the application provides a new combined drug scheme with high efficiency and low toxicity for pancreatic cancer treatment.

The invention discloses a preparation method of an abelmoschus manihot composition psoriasis external ointment, and relates to the technical field of psoriasis ointment preparation. Comprising the following steps: raw material compatibility and pretreatment: taking 10-30 parts by mass of abelmoschus manihot, 8-20 parts by mass of salvia miltiorrhiza, 5-15 parts by mass of gentiana macrophylla, 5-15 parts by mass of fried stiff silkworm, 5-15 parts by mass of ginseng, 1-5 parts by mass of prepared cantharides, 2-8 parts by mass of camphor crystals, 2-8 parts by mass of borneol, 3-10 parts by mass of mint crystals, 20-40 parts by mass of pure mutton fat and 10-30 parts by mass of olive oil. The borneol is guided into the skin, and all the medicinal materials have a synergistic effect and have a treatment effect on multiple links such as inflammation, hyperplasia and pruritus of psoriasis; a superfine grinding technology is adopted, so that the dissolution rate of effective components is greatly improved; the extraction efficiency is ensured and the loss of volatile components is avoided by adopting a segmented cooking process; the uniformity and the stability of the ointment are ensured by programmed cooling; the pure mutton fat and the olive oil are used as substrates, so that the skin affinity and the permeability are good.