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Device for measuring magnetic particles and corresponding method

A technology of measuring coils and quantitative measurement, which is applied in the direction of measuring devices, measuring magnetic variables, magnetic properties, etc., can solve problems such as complex equipment and achieve accurate measurement results

Active Publication Date: 2012-07-25
MAGNASENSE TECH OY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This complicates equipment in e.g. POCT (point of care testing) applications

Method used

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  • Device for measuring magnetic particles and corresponding method
  • Device for measuring magnetic particles and corresponding method
  • Device for measuring magnetic particles and corresponding method

Examples

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Embodiment Construction

[0029] By means of the device 10 according to the invention and the measuring method based on this device, the amount of magnetic particles from the test substrate 11 can be detected. The measurement is based on the use of a coil configuration 13, 18-20, in the operation of which the presence of magnetic particles will lead to a detectable divergence.

[0030] Figure 1-3 Some simplified examples of coils 21 suitable for use in a device 10 according to the invention for the qualitative or quantitative measurement of a magnetically labeled analyte 12 are shown.

[0031] figure 1 A first example of a coil 21 that can be applied in the device 10 is shown. In this case, the coil structure forms a planar rectangular helix, the number of turns of which is now two. The elongated test substrate 11 can be positioned quite freely, but in any case is asymmetrical with respect to the coil 21 and, more generally, with respect to the coil configuration of the device. In this case, the t...

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Abstract

The invention concerns a device (10) for the qualitative or quantitative measurement of a magnetically labelled analyte (12). The device (10) includes a coil arrangement (13, 18) for measuring the analyte (12) from a sample absorbed in a test base (11). The coil arrangement includes at least one measuring coil (13) and a reference coil arranged in connection with it. From the signal of the coil arrangement (13, 18) a change in inductance correlating to the content of the magnetically labelled analyte (12) is arranged to be detected. The change in inductance is arranged to be detected from a change (delatA, delataf) in amplitude and / or phase appearing in the output signal (32) of the coil arrangement (13, 18), which is arranged to be measured at the frequency of the input signal (31). In addition, the invention also relates to a corresponding method.

Description

technical field [0001] The invention relates to a device for the qualitative and quantitative measurement of magnetically labeled analytes, the device comprising a coil arrangement formed by at least one measuring coil and a reference coil relative to the measuring coil arrangement for measuring (test base) of the sample analyte, and arranged to detect from the signal of the coil configuration an inductance change related to the content of the magnetically labeled analyte. Furthermore, the invention also relates to a corresponding method. Background technique [0002] Many methods and devices are known from the prior art for measuring magnetic particles, eg in analytical tests. For example, Finnish Patent No. 113297 discloses the idea of ​​using a so-called haphazard coil configuration to measure an analyte from a sample absorbed in a test matrix. In this patent, a coil configuration is used to detect changes in inductance associated with the amount of magnetically labeled...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N27/72G01R33/12G01R33/341G01R33/00
Inventor 贾克·梅基兰塔朱卡·莱卡拉
Owner MAGNASENSE TECH OY