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Chinese medicine compound preparation for treating ventricular premature beat

A compound preparation and treatment room technology, which is applied in the field of traditional Chinese medicine compound preparations for the treatment of yang-deficiency coronary heart disease combined with ventricular premature beats, can solve the problems of inability to reduce mortality, large toxic and side effects, arrhythmia, etc., and achieve better curative effect and high Cost-effective, the effect of improving clinical symptoms

Inactive Publication Date: 2012-01-11
SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE PUTUO DISTRICT CENT HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinical practice shows that: lidocaine is effective for premature ventricular contractions but cannot reduce the mortality rate caused by them. arrhythmia, and the side effects are relatively large

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1 (every 1000ml contains crude drug amount, gram):

[0023] Guizhi 100 Astragalus 150 Ophiopogon japonicus 100 Safflower 50 Donkey-hide gelatin 50

[0024] Weigh each Chinese medicine according to the above weight ratio, add water and decoct twice, the first time is 2 hours, and the second time is 1 hour, combine the second medicine liquid, let it stand for 24 hours, absorb the supernatant, and concentrate under reduced pressure to relative Density 1.10 (20°C), add twice the amount of ethanol, stir evenly, let it stand for 48 hours, absorb the supernatant, recover the ethanol, and continue to concentrate to a relative density of 1.08 (20°C), add 1g of benzoic acid, ethyl hydroxyphenyl Ester 0.1g, boiled for 30 minutes, added distilled water to 1000ml, stirred evenly, filtered, potted and sealed to obtain the extract.

[0025] The extract prepared above is mixed with pharmaceutical adjuvants, and made into granules or capsules in pharmacy according to convent...

Embodiment 2

[0026] Embodiment 2 (every 1000ml contains crude drug amount, gram):

[0027] Guizhi 150 Astragalus 200 Ophiopogon japonicus 150 Safflower 100 Donkey-hide gelatin 100

[0028] Weigh each Chinese medicine according to the above weight ratio, add water and decoct twice, the first time is 2 hours, and the second time is 1 hour, combine the second medicine liquid, let it stand for 24 hours, absorb the supernatant, and concentrate under reduced pressure to relative Density 1.10 (20°C), add twice the amount of ethanol, stir evenly, let it stand for 48 hours, absorb the supernatant, recover the ethanol, and continue to concentrate to a relative density of 1.08 (20°C), add 1g of benzoic acid, ethyl hydroxyphenyl Ester 0.1g, boil for 30 minutes, add distilled water to 1000ml, stir evenly, filter and pot.

[0029] The extract prepared above is mixed with pharmaceutical auxiliary materials, and made into capsules or capsules in pharmacy according to conventional methods.

Embodiment 3

[0030] Embodiment 3 (every 1000ml contains crude drug amount, gram):

[0031] Guizhi 300 Astragalus 200 Ophiopogon japonicus 300 Safflower 50 Donkey-hide gelatin 100

[0032] Weigh each Chinese medicine according to the above weight ratio, add water and decoct twice, the first time is 2 hours, and the second time is 1 hour, combine the second medicine liquid, let it stand for 24 hours, absorb the supernatant, and concentrate under reduced pressure to relative Density 1.10 (20°C), add twice the amount of ethanol, stir evenly, let it stand for 48 hours, absorb the supernatant, recover the ethanol, and continue to concentrate to a relative density of 1.08 (20°C), add 1g of benzoic acid, ethyl hydroxyphenyl Ester 0.1g, boil for 30 minutes, add distilled water to 1000ml, stir evenly, filter and pot.

[0033] The extract prepared above is mixed with pharmaceutical adjuvants, and made into pharmaceutical extracts or dry powders or tablets according to conventional methods.

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PUM

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Abstract

The invention relates to a traditional Chinese medicine composite preparation for treating ventricular premature beat, belonging to the traditional Chinese medicine technology field, especially a traditional Chinese medicine composite preparation for treating Yang deficiency type coronary heat disease with ventricular premature beat. The medicine uses cassia twig, lilyturf root, astragalus root, safflower and ass-hide as basic remedy and adjuvant to make into granules, capsules, capsules and pills, extracts, powders or tablets, using yang-activating, migratory arthralgia, qi-supplementing andyin-nourishing, clots-absorbing and channels-activating as curative principles. The clinical trial results show that: the effective rate of the traditional Chinese medicine composite preparation on treating Yang deficiency type coronary heat disease with ventricular premature beat is 88.72% and the traditional Chinese medicine composite preparation obviously improves the clinical symptom without obvious adverse reaction. The single use of the composite preparation or combination of the composite preparation with the other medicine for treating coronary heart disease has high performance priceratio on treating Yang deficiency type coronary heat disease with ventricular premature beat.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and relates to a compound traditional Chinese medicine preparation for treating premature ventricular contractions, in particular to a compound traditional Chinese medicine preparation for treating yang-deficiency coronary heart disease combined with premature ventricular beats. Background technique [0002] Premature ventricular contractions are more common in complications of organic heart diseases such as coronary heart disease, myocarditis, and myocardial infarction. Clinical manifestations: In addition to the symptoms of the primary disease, the patient also has symptoms such as paroxysmal palpitations, chest tightness, shortness of breath, fatigue, and dizziness. The usual clinical treatment measures are as follows: mild or general ventricular premature beats usually do not require drug treatment, only the corresponding treatment for the primary disease is sufficient, ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61K9/14A61K9/16A61K9/20A61K9/48A61P9/06A61K33/36
Inventor 沈红权韩吉庞谊袁建平夏明冯青根吴文彪徐开蕾王军
Owner SHANGHAI UNIV OF TRADITIONAL CHINESE MEDICINE PUTUO DISTRICT CENT HOSPITAL
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