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Use of patchouli alcohol in preparing medicament
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A technology of potiole alcohol and drugs, which is applied in the field of medicine and can solve problems such as side effects and drug resistance
Active Publication Date: 2013-04-24
DONGGUAN MATHEMATICAL ENG ACAD OF CHINESE MEDICINE GUANGZHOU UNIV OF CHINESE MEDICINE
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However, the existing drugs not only have side effects, but also drug resistance
Method used
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Embodiment 1
[0086] Patchouli is crushed into coarse powder, passed through a 10-mesh sieve, and 2000g is taken, placed in a supercritical extraction device, and CO2 is used for supercritical extraction. The extraction conditions are: extraction pressure 12-30Mpa; extraction temperature 55-60°C; analysis pressure 5 -6Mpa; analysis temperature is 40-45°C, after 2 hours of extraction, patchouli SFE-CO containing patchouli alcohol is obtained 2 Extract, put in a clean container for later use.
[0087] Get the patchouli SFE-CO that above-mentioned makes 2 2000 mg of the extract is added with appropriate auxiliary materials, dissolved in 1000 ml of water to make an aqueous solution, dissolved, mixed evenly, subpackaged into dripping pills with a concentration of 2 mg / 1 ml per branch, sealed and sterilized. During the influenza epidemic, it is used for instillation into the nasal cavity to prevent and treat influenza.
Embodiment 2
[0089] Get the patchouli SFE-CO that embodiment 1 makes 2 200 mg of the extract is added with appropriate auxiliary materials, dissolved in 1000 ml of water to make a 0.2% aqueous solution, dissolved, mixed evenly, sealed and sterilized. During an influenza epidemic, it is used as an injection to prevent or treat influenza.
Embodiment 3
[0091] Get the patchouli SFE-CO that embodiment 1 makes 2 200 mg of the extract is added with appropriate auxiliary materials to form soft capsules containing 5% patchouli alcohol, which are sealed and sterilized. During the influenza epidemic, it is used orally to prevent or treat influenza.
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Abstract
New use of patchouli alcohol, CO2 supercritical extracts of herba pogostemonis or patchouli oil in medicament preparation is disclosed. Patchouli alcohol, having distinct inhibiting and killing effect on influenza virus H1N1, influenza virus B and avian influenza virus H5N1, can be found in both CO2 supercritical extracts of herba pogostemonis and patchouli oil.
Description
technical field [0001] The invention relates to the use of patchouli carbon dioxide supercritical extract, patchouli oil or pokichol alcohol in preparing medicines, and belongs to the field of medicine. Background technique [0002] Patchouli, Pogostemon cablin (Blanco) Benth., also known as Patchouli and Patchouli, is a plant of the genus Patchouli in the Labiatae family, a perennial herb, used for whole herbal medicine. It is native to subtropical regions such as the Philippines in Asia, and is mainly produced in Guangdong, Hainan and other places in my country. Its taste is pungent, slightly warm, and it returns to the spleen, stomach, and lung meridians. It has the effects of aromatizing turbidity, appetizing, relieving heat, etc. It is mostly used for dampness and turbidity, nausea, vomiting, fatigue due to heat-dampness, chest tightness and discomfort, cold-dampness blocking heat, abdominal pain, vomiting and diarrhea, and nasal sinusitis headache. The medicinal ingr...
Claims
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Application Information
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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/045A61K36/53A61P31/16
CPCA61K31/045A61K36/53A61P31/16
Inventor 赖小平苏子仁张奉学彭绍忠胡家敏
Owner DONGGUAN MATHEMATICAL ENG ACAD OF CHINESE MEDICINE GUANGZHOU UNIV OF CHINESE MEDICINE
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