Preparation method of traditional Chinese medicine granules capable of relieving exterior syndrome, dispelling coldness and dispersing dampness

A technology of traditional Chinese medicine granules and granules, which is applied in the directions of pharmaceutical formulations, non-central analgesics, and medical preparations with non-active ingredients, etc., can solve the problems of inconspicuous identification, difficult control, and unfavorable large-scale production, so as to enhance the therapeutic effect. , the effect of increasing the surface area and increasing the exudation rate

Active Publication Date: 2011-08-03
SICHUAN MEDCO PHARML
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Directly add notopterygium, fangfeng, atractylodes, asarum, and chuanxiong to the five medicinal materials of water distillation, and the distillation process parameters are not strictly formulated, resulting in low yield and poor quality of volatile oil, which directly affects the quality of the product and the efficacy of the drug; while the existing process is in production It is not easy to control in the process, it is not conducive to large-scale production, and it is unstable during the storage period, resulting in unclear identification; the loss of volatile components also affects the curative effect of the drug

Method used

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  • Preparation method of traditional Chinese medicine granules capable of relieving exterior syndrome, dispelling coldness and dispersing dampness
  • Preparation method of traditional Chinese medicine granules capable of relieving exterior syndrome, dispelling coldness and dispersing dampness

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1 (specification 15g / bag)

[0032] [formula]

[0033] Weigh the following Chinese medicine raw materials in the following weight proportions for later use: Notopterygium 150g, Fangfeng 150g, Atractylodes 150g, Asarum 50g, Chuanxiong 100g, Angelica 100g, Scutellaria baicalensis 100g, Licorice 100g, Rehmannia glutinosa 100g.

[0034] [preparation method]

[0035] Angelica dahurica is separately crushed into coarse powder, uniformly moistened according to the ratio of medicinal material: ethanol = 1:1, placed in an airtight place for more than 10 hours, and put into the percolation tank. Add 70% ethanol to soak for 24 hours, percolate, and the flow rate of the percolation liquid is 100L per hour; at the same time, add new 70% ethanol continuously at this speed, keep the ethanol not lower than the drug surface during the percolation process, and collect the percolation liquid as the amount of medicinal materials. 8 times, combined percolate; crush notopterygium...

Embodiment 2

[0036] Embodiment 2 (specification 15g / bag)

[0037] [formula]

[0038] Weigh the following Chinese medicine raw materials in the following weight proportions for later use: Notopterygium 150g, Fangfeng 150g, Atractylodes 150g, Asarum 50g, Chuanxiong 100g, Angelica 100g, Scutellaria baicalensis 100g, Licorice 100g, Rehmannia glutinosa 100g.

[0039] [preparation method]

[0040]Angelica dahurica is separately crushed into coarse powder, uniformly moistened according to the ratio of medicinal material: ethanol = 1:1, placed in an airtight place for more than 10 hours, and put into the percolation tank. Add 70% ethanol to soak for 24 hours, percolate, and the flow rate of the percolation liquid is 96L per hour; at the same time, add new 70% ethanol continuously at this speed, keep the ethanol not lower than the drug surface during the percolation process, and collect the percolation liquid as the amount of medicinal materials. 8 times, combined percolate; crush notopterygium, ...

Embodiment 3

[0041] Embodiment 3 (specification 15g / bag)

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PUM

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Abstract

The invention discloses a method for preparing a particle preparation of a traditional Chinese medicine for relieving exterior syndromes, dispelling coldness and dispersing dampness. The method takes notopterygium root, ledebouriella root, atractylodes rhizome, asarum herb, rhizome of Sichuan lovage, dahurian angelica root, baikal skullcap root, liquorice and rehmannia root as raw materials; the dahurian angelica root is crushed and then percolated by ethanol; the notopterygium root, ledebouriella root, atractylodes rhizome, asarum herb, rhizome of Sichuan lovage, which contain volatile components, are crushed, soaked and extracted to obtain naphtha, the medicine residues and the baikal skullcap root, liquorice and rehmannia root are mixed, added with water and subjected to extraction, concentration and alcohol deposition, and the obtained alcohol solution is mixed with the percolate of the dahurian angelica root and concentrated to be extracturm; and the obtained naphtha and the extracturm are added with proper amount of auxiliary materials for medical purpose and prepared into a particle preparation. The medicinal materials for extracting the naphtha are subjected to crushing and soaking treatment, thereby greatly improving the yield of the naphtha, improving the leaching rate of volatile active components and enhancing the curative effects of the medicine.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine pharmacy, in particular to a preparation method of granules for relieving the exterior, dispelling cold and dehumidifying. Background technique [0002] In the current Chinese medicine market, there are many traditional Chinese medicine products for relieving the exterior, dispelling cold, and dehumidifying. Among them, Jiuwei Notopterygium Granules are the most representative, which is recorded in the first chapter of "Chinese Pharmacopoeia" (2005 edition). The medicine is composed of notopterygium, Fangfeng, Cangzhu, Asarum, Chuanxiong, Angelica dahurica, Scutellaria baicalensis, licorice, and rehmannia glutinosa. achievement. Its compatibility feature is that pungent powder medicines and heat-clearing medicines are used together, it is pungent but not dry, although warming and dissipating, it does not help internal heat; It has the functions of relieving the exterior, dispersing co...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16A61K36/804A61K47/26A61K47/36A61P29/00
Inventor 余定祥
Owner SICHUAN MEDCO PHARML
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