Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Refined Yinqiao detoxification preparation and preparation method thereof

A preparation, Yinqiao technology, applied in the directions of antiviral agents, anti-inflammatory agents, pharmaceutical formulations, etc., can solve the problems of poor quality, difficult control, and imprecise formulation of distillation process parameters, and achieve the effect of stable quality enhancement and stable content.

Active Publication Date: 2012-01-11
SICHUAN MEDCO PHARML
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the existing preparation process of refined Yinqiao Jiedu Tablets, the nepeta panicle medicinal material is distilled with water, and the distillation process parameters are not strictly formulated, resulting in low yield of volatile oil and poor quality, which affects the quality of the product and the efficacy of the drug
And this process is not easy to control in the production process, which is not conducive to large-scale production; volatile components are easy to lose, which affects the clinical efficacy of drugs

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] This example is refined Yinqiaojiedu tablets (specification: each tablet contains 44mg of paracetamol)

[0025] Its raw material composition is:

[0026] Paracetamol (72g), Campanulaceae (120g), Forsythia (200g), Tempeh (100g), Licorice (100g), Bamboo Leaf (80g), Honeysuckle (200g), Arctium (120g), Nepeta Ear (80g) , Menthol (0.6g). (Total pellets 408g, about 1636 pieces)

[0027] Produced by a method comprising the following main steps:

[0028] (1), pulverize paracetamol and platycodon: pulverize the formula amount of acetaminophen and platycodon into fine powder respectively;

[0029] (2), extracting nepeta ear oil: pulverize the nepeta ear of the formula amount and pulverize the nepeta ear of the recipe amount to 10 meshes, soak for 30 minutes with 10 times the amount of water, discard the water, directly pass through steam heating, collect Fragrant water, until the taste is exhausted, and after the aromatic water is refined, Nepeta oil is obtained;

[0030] (3...

Embodiment 2

[0034] This example is refined Yinqiaojiedu granules (specification: 15g / bag, each bag contains 44mg of paracetamol)

[0035] Its raw material composition is:

[0036] Paracetamol (72g), Campanulaceae (120g), Forsythia (200g), Tempeh (100g), Licorice (100g), Bamboo Leaf (80g), Honeysuckle (200g), Arctium (120g), Nepeta Ear (80g) , Menthol (0.6g).

[0037] Produced by a method comprising the following main steps:

[0038] (1), pulverize paracetamol and platycodon: pulverize the formula amount of acetaminophen and platycodon into fine powder respectively;

[0039] (2), extraction of nepeta ear oil: pulverize the nepeta ear of the formula amount to 10-20 mesh, soak it in 10 times the amount of water for 30 minutes, discard the water, directly pass through steam heating, collect the aromatic water, and bring it to the After the taste is exhausted, the essential oil is obtained after the aromatic water is refined;

[0040] (3), dissolving nepeta oil and menthol: the menthol of ...

Embodiment 3

[0044] This example is refined Yinqiaojiedu capsules (specification: 0.3g / capsule, each capsule contains 44mg of paracetamol)

[0045] Its raw material composition is:

[0046] Paracetamol (72g), Campanulaceae (120g), Forsythia (200g), Tempeh (100g), Licorice (100g), Bamboo Leaf (80g), Honeysuckle (200g), Arctium (120g), Nepeta Ear (80g) , Menthol (0.6g).

[0047] Produced by a method comprising the following main steps:

[0048] (1), pulverize paracetamol and platycodon: pulverize the formula amount of acetaminophen and platycodon into fine powder respectively;

[0049] (2), extraction of nepeta ear oil: pulverize the nepeta ear of the formula amount to 10-20 mesh, soak it in 10 times the amount of water for 30 minutes, discard the water, directly pass through steam heating, collect the aromatic water, and bring it to the After the taste is exhausted, the essential oil is obtained after the aromatic water is refined;

[0050] (3), dissolving nepeta oil and menthol: the ment...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a refined lonicera-forsythia alexipharmic preparation, which is prepared by the following method: paracetamol and ballonflower are ground into fine powder respectively; schizonepeta spike is ground to be between 10 and 20 mesh, and then volatile oil is extracted; nepeta oil and menthol are dissolved in a proper amount of ethanol; the rest of medicines is added with water, decocted twice and filtered; filtrate is concentrated, dried and ground so as to obtain dry extract powder; the dry extract powder, the fine ballonflower powder, the fine paracetamol powder and subsidiary substances are granulated, added with a nepeta-oil ethanol solution and a menthol ethanol solution, well mixed and made into various orally-administrated preparations. In the refined lonicera-forsythia alexipharmic preparation, the nepeta oil as the component of the volatile oil is stable in content and beneficial to the stable quality of the preparation and the curative effect enhancement ofthe medicines. The invention also discloses a method for preparing the refined lonicera-forsythia alexipharmic preparation. The method is beneficial to the leaching of the volatile oil in medicinal materials so as to greatly improve the yield of the volatile oil, and has the advantages of improving the leaching rate of volatile active components, obviously increasing the content of effective substances in preparation products and strengthening the therapeutic effects of the medicines.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, in particular to a refined Yinqiao detoxification preparation and a preparation method thereof. Background technique [0002] Refined Yinqiao Jiedu Tablet is included in the "Ministry of Traditional Chinese Medicine Prescriptions" (Volume 3), page 198. 100g), pale bamboo leaves (80g), honeysuckle (200g), burdock seed (120g), nepeta ear (80g), menthol (0.6g) as raw materials, obtained by the following method: Paracetamol and Platycodon grandiflorum are respectively crushed into Fine powder, extract volatile oil from Nepeta paniculata, dissolve Nepeta paniculata oil and menthol with appropriate amount of ethanol; add other six flavors such as Forsythia suspensa to water for two times, filter, combine the filtrate, concentrate the filtrate into paste, add platycodon grandiflorum, paracetamol powder and Appropriate amount of auxiliary materials, mix well, make into ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A61P31/16A61P29/00A61P25/04A61P11/04A61P11/14A61K31/045A61K31/167
Inventor 卿光明余定祥钟瑛
Owner SICHUAN MEDCO PHARML
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com