Method for preparing superfine liver-fire-purging and spleen-stomach-regulating pill

Abstract

The invention relates to a Chinese patent medicine for treating gastric cavity burning pain, vomiting and acid regurgitation, bitter taste and epigastric upset as well as abdominal pain and diarrhea due to liver-stomach disharmony, in particular to an oral water pill preparation which is mainly prepared from the traditional Chinese patent medicine by a superfine grinding method. As for an ordinary liver-fire-purging and spleen-stomach-regulating pill (water pill), bulk drugs are crushed into fine powder according to relevant regulations, and the bulk drugs are generally ground into 80-100 meshes not less than 95%, the degree of fineness of the crushed bulk drugs is an important guarantee for the pill quality. The superfine grinding technology is adopted to crush the bulk drugs into 5-75mum particle size distribution. The superfine grinding technology aims at overcoming disadvantages of the traditional preparation technology of the liver-fire-purging and spleen-stomach-regulating pill, and ensuring granularity uniformity. The invention provides the superfine liver-fire-purging and spleen-stomach-regulating pill with denser, more smooth and uniform-color surface, rapid drug release, quick effect, high bioavailability and more convenient drug administration.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to an ultrafine preparation method of Wuji Pills, a Chinese patent medicine for treating diseases of the spleen and stomach. Background technique [0002] The preface of "Shen Nong's Materia Medica", a classical Chinese medical book, pointed out: "There are medicines that are suitable for pills." "Su Shen Liang Fang" said: "The big poisoner must use pills." Since the Han and Jin Dynasties, it has been proposed: "Pills are based on soothing", and "Pills are soothing". After taking the pill, it disintegrates slowly in the gastrointestinal tract, releases the drug gradually, and has a long-lasting effect; it can delay the absorption of poisonous, violent and irritating drugs, and weaken the toxicity and adverse reactions. Therefore, pills are often used for clinical treatment of chronic diseases (such as spleen and stomach diseases) or chronic illness and infi...

AI Technical Summary

Problems solved by technology

[0013] (3) Improve the utilization rate of medicinal materials The survey of medicinal resources shows that due to the imperfect management mechanism of wild medicinal resources in our country, the phenomenon of random picking that does not follow scientific laws is still quite serious in some areas, resulting in the depletion of some valuable Chinese medicinal materials. At the same time, due to the excessive growth of consumption of Chinese herbal medicines, the contradiction between supply and demand has become increasingly prominent, which has led to a substantial increase in the price of Chinese herbal medicines

However, due to the limited retention time of the drug in the gastrointestinal tract, the active ingredients in the cells have not been completely dissolved during this period, which affects the absorption in the body.

And because the surface of ordinary water pan pills is not delicate enough, it is easy to cause some irritation to the gastric mucosa after taking it. For patients with spleen and stomach diseases, it is easy to produce symptoms such as vomiting.

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