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Biological vision assisting system

A biological and object technology, applied in the field of biological vision aid system, to achieve the effect of restoring visual function

Active Publication Date: 2011-02-16
深圳市比较医学技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] In view of this, it is necessary to provide a biological vision aid system that does not require surgery to address the problem of using artificial eyes through surgery.

Method used

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Experimental program
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Embodiment Construction

[0024] The biological vision aid system includes a pharmaceutical carrier containing a recombinant lentiviral vector, a positioning device, an injection device and a light emitting device.

[0025] The recombinant lentiviral vector carries a light-sensitive gene or its functional fragment regulated by a cell-specific promoter. The gene encoding light-sensitivity may be an excitatory channel protein gene (Channelrhodopsin-2, ChR2) or a gene having the same function as ChR2 (such as ChR2-310, Chop2 or Chop2-310). The ChR2 protein is a rhodopsin originating from the unicellular green alga Chlamydomonas Reinhardtii. The rhodopsin protein ChR2 is composed of a molecule of opsin and a chromophore called retinal. ChR2 is sensitive to blue light, which will make Na + Wait for cations to enter the cell and excite the cell. The wavelength range of the blue light is 450nm-490nm, and in particular, ChR2 is most sensitive to the blue light with a wavelength of 470nm.

[0026] The polyn...

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Abstract

The invention relates to a biological vision assisting system which comprises a positioning device, an injection device a light emitting device, and a pharmaceutical carrier containing a recombining sThe invention relates to a biological vision assisting system which comprises a positioning device, an injection device a light emitting device, and a pharmaceutical carrier containing a recombining s the light with a specific wave length. The invention has the advantage that no surgery is needed in the using process of the biological vision assisting system.to the light with a specific wave length. The invention has the advantage that no surgery is needed in the using process of the biological vision assisting system.low virus vector, wherein the recombining slow virus vector carries a coding light sensitive gene controlled by a special cell promoter, the positioning device is used for determining a position of thlow virus vector, wherein the recombining slow virus vector carries a coding light sensitive gene controlled by a special cell promoter, the positioning device is used for determining a position of the retina of a user, the injection device is used for injecting the pharmaceutical carrier which contains the recombining slow virus vector into the retina of the user, the light emitting device is usee retina of a user, the injection device is used for injecting the pharmaceutical carrier which contains the recombining slow virus vector into the retina of the user, the light emitting device is used for emitting light with a specific wave length to illuminate an object positioned in front of the eyes of the user, a part of the light with a specific wave length can enter the eyes of the user aftd for emitting light with a specific wave length to illuminate an object positioned in front of the eyes of the user, a part of the light with a specific wave length can enter the eyes of the user after the light with a specific wave length is reflected by the object positioned in front of the eyes of the user, and the coding light sensitive gene controlled by a special cell promoter is sensitiveer the light with a specific wave length is reflected by the object positioned in front of the eyes of the user, and the coding light sensitive gene controlled by a special cell promoter is sensitiveto

Description

technical field [0001] The invention relates to a biological vision aid system. Background technique [0002] Blindness, commonly known as blindness or blindness. According to the statistics of the World Health Organization in 2003, there are more than 40 million people suffering from blindness in the world. One of the most common causes is a lesion in the retina that causes photoreceptor cells to degenerate and even die. Current methods focus on improving the visual function of people with low vision. [0003] One approach is an artificial eye. At present, the artificial eye with good therapeutic effect mainly includes optic nerve stimulator. An optic nerve stimulator is a ferrule with microelectrodes attached to the optic nerve. The image is digitized by an external camera, and the electrical signal is transmitted to the ferrule, so that the optic nerve is stimulated to generate a visual signal. [0004] However, the use of artificial eyes requires surgery to implant...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61F9/08A61K48/00A61P27/02
Inventor 王立平张奕蔚鹏飞
Owner 深圳市比较医学技术有限公司
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