Application method of natural plant rhizoma smilacis glabrae extract

A soil Poria extract and natural plant technology, applied in the field of antipruritic active ingredients and skin anti-allergy, can solve problems such as damage to the gastrointestinal digestive system, inability to fundamentally improve allergic constitution, etc., and achieve the effect of small side effects

Inactive Publication Date: 2009-12-30
泊恩诗(上海)化妆品有限公司 +4
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the currently synthesized antihistamines have side effects such as drowsiness, thirst, and damage to the gastrointestinal digestive system in clinical use, and there are

Method used

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  • Application method of natural plant rhizoma smilacis glabrae extract
  • Application method of natural plant rhizoma smilacis glabrae extract

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0029] Example 1

[0030] Take 100g of Poria cocos, extract A is pure water, configure eluent B: deionized water, C: 30% ethanol aqueous solution (V / V), choose non-polar resin: HZ891, technical medicine: extract: resin: Eluent B:Eluent C = 1:10:3:12:9.

[0031] After crushing the tuckahoe, soak it in extract A at 30°C for 72 hours, and concentrate it to a medicinal solution with a crude drug concentration of about 1 mg / ml. After being adsorbed by HZ891, it is eluted with B, and the eluent is discarded, and the eluent C is collected for washing. off the paragraph. Concentrate to extract to obtain Poria cocos extract.

Example Embodiment

[0032] Example 2

[0033] Take 100g of Poria cocos, extract A is pure water, configure eluent B: deionized water, C: 30% ethanol aqueous solution (V / V), choose non-polar resin: D101, technical drug: extract: resin: Eluent B:Eluent C = 1:10:3:12:12.

[0034] After crushing the tuckahoe, it was extracted with extract A at 50°C for 5 hours, concentrated to a medicinal solution with a crude drug concentration of about 1 mg / ml, adsorbed by D101, eluted with B, and then discarded with eluent B, and collected eluent C. Elution segment. Concentrate to extract to obtain Poria cocos extract.

Example Embodiment

[0035] Example 3

[0036] Take 100g of Poria cocos, extract A is pure water, configure eluent B: deionized water, C: 30% methanol aqueous solution (V / V), select non-polar resin: H103, technical drug: extract: resin: Eluent B:Eluent C = 1:8:2:9:12.

[0037] After pulverizing the tuckahoe, extract it three times with extract A at 80 °C for 2 hours each time, and concentrate it to a medicinal liquid with a crude drug concentration of about 1 mg / ml. Eluent C elution segment. Concentrate to extract to obtain Poria cocos extract.

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Abstract

The invention relates to an application method of a natural plant rhizoma smilacis glabrae extract. In the application method, the natural plant rhizoma smilacis glabrae extract is applied to medicines, cosmetics and health-care foods for suppressing histamine release. The invention adopts a test model suppressing the histamine release of mass cells and validates the irritability-resisting and itching-relieving effects of the natural plant rhizoma smilacis glabrae extract.

Description

technical field [0001] The invention relates to an effective active ingredient for anti-allergic and antipruritic skin, the active ingredient is a natural plant Smilax smilax extract, in particular to an application method of the natural plant Smilax smilax extract. Background technique [0002] Epidemiological surveys in recent years have shown that allergic diseases have an increasing trend year by year, especially allergic reactions caused by environmental factors and anti-hereditary atopic dermatitis, which have become a social phenomenon that cannot be ignored. The emergence of its problems is not only due to the increase of allergens, air pollution, abuse of food and cosmetic additives, but also due to changes in people's eating habits in recent years. The treatment of allergic diseases is usually based on the elimination of allergens, and then selective drug treatment is carried out according to the degree, cause and pathogenesis of clinical symptoms. Common allergie...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K8/97A61Q19/00A61P37/08A61P17/04A23L1/30
Inventor 李成亮
Owner 泊恩诗(上海)化妆品有限公司
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