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Eriosema chinense flavonoid extract and extracting method and application thereof

An extraction method and a flavonoid technology, which are applied in the field of medicine, can solve the problems of unclear clinical drug use mechanism, unknown active ingredients, and inability to elucidate the pharmacodynamic material basis and action mechanism of traditional Chinese medicine for treating diseases, so as to prolong cough incubation period, Effect of suppressing ear swelling effect, good anti-inflammatory effect

Inactive Publication Date: 2010-03-17
FUJIAN AGRI & FORESTRY UNIV
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Although Zhuzai Li has been widely used among the people, there are no relevant literature reports on the active ingredients and biological activities of Zhuzai Li, and the clinical mechanism of Zhuzai Li is not yet clear. The range of clinical application has not been fully and effectively developed and utilized
At the same time, due to the unknown main active ingredients, it is impossible to detect the active ingredients of Zhuzai Li, effectively control the quality of medicinal materials, and conduct authoritative identification of authentic medicinal materials
[0003] Among the many studies of traditional Chinese medicine, there are few studies on active ingredients, pharmacological effects, and the relationship between drug efficacy and ingredients, so it is impossible to clarify the material basis of Chinese medicine efficacy in treating diseases and mechanism of action and other important scientific issues, nor can it provide a lead or structural core for finding new drugs or synthesizing new drugs, and cannot improve the research methods and technical level of new Chinese medicines

Method used

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  • Eriosema chinense flavonoid extract and extracting method and application thereof
  • Eriosema chinense flavonoid extract and extracting method and application thereof
  • Eriosema chinense flavonoid extract and extracting method and application thereof

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Embodiment Construction

[0017] Below in conjunction with embodiment the present invention is described in detail:

[0018] The first part study on the chemical constituents of the petroleum ether extract of piglets

[0019] 1 Experimental instruments and materials

[0020] 1.1 Medicinal materials

[0021] Zhuzai hat was purchased from location: Longyan, Fujian; identification: identification by researcher Wang Zhendeng of Fujian Academy of Traditional Chinese Medicine.

[0022] 1.2 Instruments

[0023] Microanalytical balance (Beijing Sartorius Balance Co., Ltd.); RE-52A rotary evaporator (Shanghai Yarong Biochemical Instrument Factory); constant temperature water bath; partial collector (Shanghai Huxi Analytical Instrument Factory Co., Ltd.); ultrasonic cleaner ( Kunshan Ultrasound Instrument Co., Ltd.); UV-Vis Spectrophotometer (VARIAN, Cary 50); AVATAR360 Infrared Spectrometer (Thermo Nicoler, USA); GS 20 Analytical High Speed ​​Countercurrent Chromatography (Beijing Tianbao Wuhua Biotechnology...

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Abstract

The invention discloses an eriosema chinense flavonoid extract and an extracting method and application thereof. The eriosema chinense flavonoid extract has the structure as shown on the right: the traditional refluxing extracting method of solvent is used, and HSCCC is combined with the traditional preparation method of thin-layer chromatography for separation and purification so as to obtain a new compound separated from the part of petroleum ether of eriosema chinense flavonoid. The eriosema chinense flavonoid extract has antibacterial effect, anti-inflammatory effect, and the effects of relieving cough and reducing phlegm.

Description

Technical field: [0001] The invention relates to an extract of flavonoids from piglets and its preparation method and application, belonging to the field of medicine. Background technique: [0002] The genus Eriosema chinense Vog is a plant of the genus Fabaceae, about 100 species, distributed in tropical and subtropical regions. According to the "Dictionary of Chinese Medicine", the roots of piglets are used as medicine, which has the effects of clearing away heat and detoxification, generating heat and polydipsia, reducing phlegm and moisturizing the lungs, and relieving cough. Rare and valuable Chinese herbal medicine for injuries and other diseases. Zhuzai Li is mainly used to treat cough and asthma. It has remarkable curative effect, is safe and reliable, cheap and convenient. It is a good resource of Chinese herbal medicine and is worthy of development, research and popularization. Although Zhuzai Li has been widely used among the people, there are no relevant litera...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07D493/04A61K31/352A61P31/00A61P29/00A61P11/14A61P11/12A61P11/10A61P31/04
Inventor 李清禄李凌峰李宇翔黄美玲
Owner FUJIAN AGRI & FORESTRY UNIV
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