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Chinese medicinal composition for treating pyelonephritis

A technology of pyelonephritis and composition, applied in the field of traditional Chinese medicine preparations, can solve the problems of slow control of clinical symptoms, unsatisfactory recovery of patients' health, kidney damage, etc.

Inactive Publication Date: 2010-06-23
BEIJING ZHONGKE RENHE SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The application of these drugs sometimes has no obvious drug effect, or allergic reactions, or certain damage to the kidneys, and after long-term use of antibiotics, bacteria develop drug resistance, or enter cells, causing the antibiotics to lose their bactericidal ability
At the same time, this treatment method is slow to control the patient's clinical symptoms, and the time for proteinuria and clean urine culture to turn negative is relatively slow, which is not ideal for the patient's health recovery, and it is easy to relapse. Due to the continuous recurrence of the disease, it will gradually shrink and fail. And must do kidney dialysis, even life-threatening
In terms of Chinese patent medicines, there are few Chinese patent medicines that have a high curative effect on pyelonephritis

Method used

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  • Chinese medicinal composition for treating pyelonephritis
  • Chinese medicinal composition for treating pyelonephritis
  • Chinese medicinal composition for treating pyelonephritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Adopt the following ratio of Chinese herbal medicine raw material formula:

[0049] Honeysuckle 80g Akebia 50g Scutellaria baicalensis 30g

[0050] Gardenia 45g Rhubarb 30g Cuscuta 60g

[0051] Lycium barbarum 20g Alisma 70g Yam 20g

[0052] Licorice 40g

[0053] Its preparation method is:

[0054] Take each medicinal material, mix, add water and decoct twice, each time add 8 times the amount of water, decoct for 1 hour each time, combine the decoction, filter, concentrate the filtrate, add ethanol to the concentrated solution, so that the alcohol content reaches 40% (V / V), refrigerate and stand overnight, take the supernatant night, recover ethanol under reduced pressure until it has no alcohol smell, concentrate it into a thick paste with a relative density of 1.38 (60°C), dry it under reduced pressure, crush it into fine powder, add stevia About 0.8g of prime, about 94g of dextrin, mix evenly, make granules with 90% ethanol, dry, granulate, pack separately, and g...

Embodiment 2

[0056] Adopt the following ratio of Chinese herbal medicine raw material formula:

[0057]Honeysuckle 150g Akebia 95g Scutellaria baicalensis 65g

[0058] Gardenia 80g Rhubarb 55g Cuscuta 90g

[0059] Lycium barbarum 45g Alisma 100g Yam 45g

[0060] Licorice 60g

[0061] Its preparation method is:

[0062] Take each medicinal material, mix, add water and decoct 3 times, each time add 10 times the amount of water, decoct for 1 hour each time, combine the decoction, filter, concentrate the filtrate, add ethanol to the concentrated solution, so that the alcohol content reaches 50% (V / V), refrigerate and stand overnight, take the supernatant night, recover ethanol under reduced pressure until it has no alcohol smell, concentrate it into a thick paste with a relative density of 1.36 (70°C), dry it under reduced pressure, crush it into a fine powder, add sucrose About 76g of powder, about 165g of starch, mixed evenly, made into granules with 75% ethanol, dried, granulated, divid...

Embodiment 3

[0064] Adopt the following ratio of Chinese herbal medicine raw material formula:

[0065] Honeysuckle 190g Akebia 120g Scutellaria baicalensis 90g

[0066] Gardenia 100g Rhubarb 80g Cuscuta 120g

[0067] Lycium barbarum 75g Alisma 140g Yam 70g

[0068] Licorice 80g

[0069] Its preparation method is:

[0070] Take each medicinal material, mix, add water to decoct 4 times, add 12 times of water each time, decoct for 1 hour each time, combine the decoction, filter, concentrate the filtrate, add ethanol to the concentrated solution to make the alcohol content reach 60% (V / V), refrigerate and stand overnight, take the supernatant night, recover ethanol under reduced pressure until it has no alcohol smell, concentrate it into a thick paste with a relative density of 1.32 (80°C), dry it under reduced pressure, crush it into a fine powder, add sucrose About 94g of powder, about 226g of the mixture of starch and lactose (ratio: 5:2), mix evenly, make granules with 60% ethanol, dr...

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Abstract

The invention disclose a Chinese medicinal composition for treating pyelonephritis, belonging to the technical field of Chinese materia medica preparation. The Chinese medicinal composition is granules which are prepared according to different characteristics of each Chinese medicament in proportion by using honeysuckle flower, akebia stem, baical skullcap root, gardenia, rhubarb, south dodder seed, barbary wolfberry fruit, oriental waterplantain rhizome, common yam rhizome and liquoric root as the raw materials through the steps of water extraction, drying and grinding. The Chinese medicinal composition has effects of clearing away heat and toxic material and inducing diuresis for treating strangurtia, and is used for treating frequent micturition, urgent urination, yellow urine or lumbago and lower abdomen pain which are caused by damp-heat in lower-jiao and pyelonephritis with the syndromes. The pharmacological tests prove that the Chinese medicinal composition has effect of obviously reducing leucocyte amount and occult blood in the urine, has obvious curative effect of treating pyelonephritis caused by bacterial infection, and has characteristics of relapse prevention after heating, no toxic or side effects and the like.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a traditional Chinese medicine composition for treating pyelonephritis, the dosage form of which is granules. Background technique [0002] Pyelonephritis is more common in women and belongs to the category of gonorrhea in traditional Chinese medicine. It is an inflammatory disease of the renal pelvis or renal parenchyma. Most of it is caused by bacterial infection. It is generally difficult to cure and easily recurs. At present, it is known that the treatment of pyelonephritis mostly adopts the treatment method of hormone plus antibiotics, such as penicillin, kanamycin, gentamycin and other antibacterial drugs. The application of these drugs sometimes has no obvious drug effect, or allergic reactions, or certain damage to the kidneys, and after long-term use of antibiotics, bacteria develop drug resistance, or enter cells, making the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P13/12
Inventor 颜丽君
Owner BEIJING ZHONGKE RENHE SCI & TECH
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