Method for preparing granules for curing infantile lung pathogenic heat and cough and asthma

A technology for lung-heat Kechuan and granules, which is applied in the field of preparation of children's lung-heat Kechuan granules, can solve the problems of unstable preparation quality, unstable baicalin identification items, low product qualification rate, etc., and achieves stable baicalin identification items. , controllable quality, good effect

Active Publication Date: 2010-07-21
HAINAN HULUWA PHARMA GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The above-mentioned clear paste is a water extraction product, and the Xiaoerfeirekechuan granules made are produced according to the prior art because the product quality standard contains the identification item of baicalin, and baicalin is insoluble in water (dissolved under alkaline conditions). Can not be fully extracted, resulting in unstable identification items of baicalin in the product, resulting in unstable preparation quality and low product pass rate

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Weigh the following Chinese herbal medicines:

[0038] Ephedra 30g Bitter almond 60g Gypsum 240g Licorice 30g

[0039] Honeysuckle 100g Forsythia 100g Anemarrhena 100g Scutellaria baicalensis 100g

[0040] Radix Radix 100g Ophiopogon japonicus 100g Houttuynia cordata 100g;

[0041] Prepare as follows:

[0042] (1) Weigh the two medicinal materials of Scutellaria baicalensis and ephedra, mix them well, add water and decoct them twice, each time for 1 hour, the amount of water each time is 5 times the total weight of the two medicinal materials, combine the two extracts, and filter The filtrate is ready for use;

[0043] (2) Weigh bitter almonds, raw gypsum, licorice, honeysuckle, Anemarrhena, forsythia, Radix Radix, Ophiopogon japonicus and Houttuynia cordata, mix them well, add water to decoct twice, each time for 1 hour, each time The dosage is 5 times of the total weight of Jiuwei medicinal materials, the 2 extracts are combined, and the filtrate is filtered for s...

Embodiment 2

[0046] Weigh the following Chinese herbal medicines:

[0047] Ephedra 30g Bitter almond 60g Gypsum 240g Licorice 30g

[0048] Honeysuckle 100g Forsythia 100g Anemarrhena 100g Scutellaria baicalensis 100g

[0049] Radix Radix 100g Ophiopogon japonicus 100g Houttuynia cordata 100g;

[0050] Prepare as follows:

[0051] (1) Weigh the two medicinal materials of forsythia and ephedra, mix them evenly, add water and decoct them twice, 1 hour each time, the amount of water for each time is 3 times the total weight of the two medicinal materials, combine the two extracts, and filter The filtrate is used for later use;

[0052] (2) Weigh bitter almonds, raw gypsum, licorice, honeysuckle, Anemarrhena, scutellaria, Radix Isatidis, Ophiopogon japonicus and Houttuynia cordata, mix well, add water and decoct twice, each time for 1 hour, the amount of water used each time It is 8 times of the total weight of Jiuwei medicinal materials, the 2 extracts are combined, and the filtrate is fil...

Embodiment 3

[0055] Weigh the following Chinese herbal medicines:

[0056] Ephedra 30g Bitter almond 60g Gypsum 240g Licorice 30g

[0057] Honeysuckle 100g Forsythia 100g Anemarrhena 100g Scutellaria baicalensis 100g

[0058] Radix Radix 100g Ophiopogon japonicus 100g Houttuynia cordata 100g;

[0059] Prepare as follows:

[0060] (1) Weigh the two medicinal materials of forsythia and ephedra, mix them well, add water to decoct twice, each time for 1 hour, the amount of water each time is 8 times the total weight of the two medicinal materials, combine the two extracts, filter The filtrate is used for later use;

[0061] (2) Weigh bitter almonds, raw gypsum, licorice, honeysuckle, Anemarrhena, scutellaria, Radix Isatidis, Ophiopogon japonicus and Houttuynia cordata, mix well, add water and decoct twice, each time for 1 hour, the amount of water used each time It is 3 times the amount of the total weight of Jiuwei medicinal materials, the 2 extracts are combined, and the filtrate is filt...

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Abstract

The invention discloses a method for preparing granules for curing infantile lung pathogenic heat and cough and asthma. The method comprises the following steps: weighing the following Chinese medicinal materials in part by weight: 30 parts of ephedra, 60 parts of bitter almond kernel, 240 parts of raw gypsum, 30 parts of liquorice root, 100 parts of honeysuckle, 100 parts of weeping forsythiae capsule, 100 parts of anemarrhena root, 100 parts of baikal skullcap root, 100 parts of indigowoad root, 100 parts of dwarf lilyturf tuber and 100 parts of cordate houttuynia; dividing the eleven Chinese medicinal materials into two groups; after performing water extraction on the two groups of Chinese medicinal materials, combining filtrates; mixing an extract prepared by concentrating the filtrate with a proper amount of dextrine and sodium cyclamate; preparing the mixture into granules; and drying the granules to obtain the granules for curing the infantile lung pathogenic heat and cough and asthma. In the method, water use amount in the process of performing water extraction on the Chinese medicinal materials is strictly controlled and extraction in different groups is carried out according to characteristics of different medicinal materials, so compared with a traditional water extraction method, the method has a better effect. The prepared granules for curing the infantile lung pathogenic heat and cough and asthma have stable and controllable quality, and stable baicalin distinguish project which meets requirements of standard. The method greatly improves qualification rate of the product, and has simple operation and is suitable for industrial production.

Description

technical field [0001] The invention relates to the field of preparation of pharmaceutical preparations, in particular to a preparation method of Xiaoer Feire Kechuan Granules. Background technique [0002] Existing cough and asthma preparations for children with lung heat are generally made of eleven traditional Chinese medicinal materials such as ephedra, bitter almond, raw gypsum, licorice, honeysuckle, forsythia, Anemarrhena, scutellaria, Radix Radix, Ophiopogon japonicus and Houttuynia cordata. It has the effects of clearing heat and detoxifying, clearing lung and relieving cough, resolving phlegm and relieving asthma. Clinical practice has proved that it has a very significant curative effect on colds, bronchitis, asthmatic bronchitis, and bronchopneumonia. [0003] Most of the children's Feire Kechuan preparations are based on the Ministry of Health's drug standards for traditional Chinese medicine preparations, volume 18, page 14 of the Pediatric Feire Kechuan Granul...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K9/16A61P11/06A61P11/14A61K33/06
Inventor 刘全国
Owner HAINAN HULUWA PHARMA GRP CO LTD
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