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Application of composite containing polygonum orientale in preventing and treating climacteric diseases and delaying aging

A kind of composition, the technology of oriental grass, applied in the application field of medicine, can solve the problems such as no menopausal diseases and senescence prevention and control.

Active Publication Date: 2010-09-29
GUIZHOU YIBAI PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is mainly used for coronary heart disease angina pectoris with heart-blood stasis syndrome, symptoms include chest tightness, chest pain, immobility, palpitations, dark purple lips and tongue, thready and astringent pulse, etc. Coronary heart disease angina pectoris with the above syndromes, no use of the above-mentioned drugs has been used so far. Report on Clinical Pharmacological Research of Composition on Prevention and Treatment of Climacteric Diseases and Aging

Method used

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  • Application of composite containing polygonum orientale in preventing and treating climacteric diseases and delaying aging
  • Application of composite containing polygonum orientale in preventing and treating climacteric diseases and delaying aging
  • Application of composite containing polygonum orientale in preventing and treating climacteric diseases and delaying aging

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0134] 5 parts of Chinese Radix, 4 parts of hawthorn leaves, 3 parts of Panax notoginseng and 3 parts of Rhizoma Chuanxiong (parts are parts by weight, and the following examples are parts by weight)

[0135] Add 10 times the amount of water to decoct Chinese weed grass, hawthorn leaves, and Panax notoginseng 3 times, each time for 1 hour, filter, combine the filtrate, concentrate under reduced pressure to a relative density of 1.10, add ethanol to make the alcohol content reach 65%, stir evenly, Stand still for 12 hours, filter with suction, recover ethanol from the filtrate under reduced pressure and concentrate to a relative density of 1.07, add an appropriate amount of water to dilute, use a macroporous adsorption resin column with an upper diameter to height ratio of 1:10, and an adsorption flow rate of 2BV·h -1 , discard the breakthrough solution, wash with 1BV water, flow rate 2BV·h -1 , discard the water washing solution, and then eluted with 3BV70% ethanol at a flow r...

Embodiment 2

[0138] The Ligusticum chuanxiong extract obtained in Example 1 is added to the extract mixture of sage, hawthorn leaves, and Panax notoginseng, and then an appropriate amount of soybean oil containing 2% beeswax is added, mixed evenly, and set aside; use gelatin: glycerin: distilled water: preservative Gold methyl ester) = 1: 0.4: 1: 0.002 to prepare capsule material, and press to obtain soft capsules.

Embodiment 3

[0140] 6 parts of Chinese weed, 5 parts of hawthorn leaves, 4 parts of Panax notoginseng and 3 parts of Chuanxiong

[0141] Add 10 times the amount of water to decoct the weed grass and hawthorn leaves 3 times, 1 hour each time, filter, combine the filtrate, concentrate under reduced pressure to a relative density of 1.10, add ethanol to make the alcohol content reach 65%, stir evenly, and let stand for 12 hour, suction filtration, the filtrate decompressed to recover ethanol and concentrate to a relative density of 1.07, add appropriate amount of water to dilute, the upper diameter height ratio of 1:10 macroporous adsorption resin column, adsorption flow rate 2BV h -1 , discard the breakthrough solution, wash with 1BV water, flow rate 2BV·h -1 , discard the water washing solution, and then eluted with 3BV70% ethanol at a flow rate of 2BV·h -1 , collecting the eluate, recovering ethanol, concentrating into a thick paste, spray-drying the residue, and pulverizing into a fine p...

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Abstract

The invention discloses the application of a composite containing polygonum orientale in preparing medicaments for preventing and treating climacteric diseases and delaying aging. The composite is prepared from extracts of polygonum orientale, panax notoginseng, hawthorn leaves and Rhizoma Chuanxiong. The invention provides a novel medical application of the composite containing polygonum orientale and a new medicine selection for patients.

Description

technical field [0001] The invention relates to the application of the composition, in particular to the application of the composition containing the sage in preparation of medicines for preventing and treating menopausal diseases and delaying aging. technical background [0002] Menopause is an important stage in life. At this stage, people's physiology changes greatly. The immune function against diseases decreases, the function of the neuroendocrine system gradually declines, and the level of hormones decreases, which often brings a series of physical diseases and emotional disorders. At the same time, they are under pressure from work, study, family, marriage and all aspects of society, so there are also obvious psychological changes. [0003] Women transition from childbearing age to old age, due to a series of changes brought about by ovarian dysfunction, such as high blood pressure, flushing, dizziness, tinnitus, vertigo, insomnia, memory loss, anxiety, depression, n...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/734A61K36/704A61P15/12A61P19/10A61P25/24A61P39/06
Inventor 窦啟玲
Owner GUIZHOU YIBAI PHARMA CO LTD
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