Chinese medicinal composition for treating pelvic inflammation and preparation method thereof

A composition and technology for pelvic inflammatory disease, applied in the field of traditional Chinese medicine compositions, can solve problems such as superinfection, long course of treatment for chronic pelvic inflammatory disease, poor effect of chronic pelvic inflammatory disease, etc.

Active Publication Date: 2010-10-06
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Western medicine treats pelvic inflammatory disease mainly with antibacterial and anti-inflammatory effects. Western medicine uses antibiotics to control sensitive bacterial infections in acute pelvic inflammatory disease, but is less effective for chronic pelvic inflammatory disease, and antibiotics do not have the effect of relieving adhesions and relieving pain, and long-term use of antibiotics can easily lead to drug resistance Bacteria and superinfection; and traditional Chinese medicine has a coup for the treatment of pelvic inflammatory disease. The course of treatment for chronic pelvic inflammatory disease is relatively long, so the treatment is more complicated than acute pelvic inflammatory disease. Traditional Chinese medicine therapy is usually used for treatment. Chinese medicine treatment, internal and external treatment , and pay attention to the combination of local and overall, tackling and strengthening, so the curative effect is satisfactory, and there are no toxic and side effects, and it has broad development prospects

Method used

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  • Chinese medicinal composition for treating pelvic inflammation and preparation method thereof
  • Chinese medicinal composition for treating pelvic inflammation and preparation method thereof
  • Chinese medicinal composition for treating pelvic inflammation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0308] Embodiment 1: Capsules

[0309] prescription:

[0310] Saponin thorn 100g Polygonum cuspidatum 100g Dandelion 120g Red vine 120g

[0311] Radix Paeoniae Alba 100g Yuanhu 120g Codonopsis 120g

[0312] Preparation method: (1) Take Radix Paeoniae Rubra and Polygonum cuspidatum, add 10 times the amount of 80% ethanol to soak for 1.5 hours, reflux extraction for 1.5 hours, filter, and collect the filtrate; add 8 times the amount of 80% ethanol to reflux extraction for 1.5 hours, filter , combine the filtrates, recover ethanol under reduced pressure and concentrate to a relative density of 1.15-1.20, and dry under reduced pressure to obtain Intermediate I;

[0313] (2) Take dandelion, red rattan, saponins, soak in 15 times the amount of water for 2 hours, extract for 1.5 hours, filter, and collect the filtrate; add 13 times the amount of water to decoct the medicinal residues, extract for 1.5 hours, filter, and combine The filtrate was concentrated under reduced pressure t...

Embodiment 2

[0318] Embodiment 2: capsules

[0319] prescription:

[0320] Saponin thorn 70g Polygonum cuspidatum 70g Dandelion 140g Red vine 140g

[0321] Radix Paeoniae Alba 70g Yuanhu 140g Codonopsis 140g

[0322] Preparation method: (1) take Radix Paeoniae Rubra and Polygonum cuspidatum plus 6 times the amount of 70% ethanol, soak for 1 hour, reflux extraction for 2.5 hours, filter, and collect the filtrate; add 6 times the amount of 70% ethanol for reflux extraction, filter , combine the filtrates, recover ethanol under reduced pressure and concentrate to a relative density of 1.15-1.20, and dry under reduced pressure to obtain Intermediate I;

[0323] (2) Take dandelion, red rattan, saponins and add 10 times the amount of water to soak for 1 hour, extract for 2 hours, filter, and collect the filtrate; add 10 times the amount of water to extract the medicinal residues for 2 hours, filter, and combine the filtrates, Concentrate under reduced pressure to a relative density of 1.05 to...

Embodiment 3

[0328] Embodiment 3: capsules

[0329] prescription:

[0330] Saponin thorn 100g Polygonum cuspidatum 100g Dandelion 150g Red vine 150g

[0331] Radix Paeoniae Alba 100g Yuanhu 150g Codonopsis 150g

[0332] Preparation method: (1) Take Radix Paeoniae Rubra and Polygonum cuspidatum, add 8 times the amount of 80% ethanol to soak for 2 hours, reflux extract for 1 hour, filter, and collect the filtrate; add 10 times the amount of 80% ethanol for reflux extraction for 1 hour, filter , combine the filtrates, recover ethanol under reduced pressure and concentrate to a relative density of 1.15-1.20, and dry under reduced pressure to obtain Intermediate I;

[0333] (2) Take dandelion, red rattan, saponins and add 10 times the amount of water to soak for 1 hour, extract for 2 hours, filter, and collect the filtrate; add 15 times the amount of water to extract the dregs for 2.5 hours, filter, and combine the filtrates, Concentrate under reduced pressure to a relative density of 1.05 t...

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Abstract

The invention relates to a Chinese medicinal composition, in particular to a Chinese medicinal composition for treating pelvic inflammation and a preparation method thereof. The Chinese medicinal composition comprises the following raw material medicaments in part by weight: 5 to 15 parts of Chinese honeylocust spine, 5 to 15 parts of giant knotweed rhizome, 7 to 17 parts of mongolian dandelion herb, 7 to 17 parts of sargentgloryvine stem, 5 to 15 parts of red paeony root, 7 to 17 parts of rhizoma corydalis and 7 to 17 parts of szechwon tangshen root. The Chinese medicinal composition can be prepared into tablets, capsules, pills, granules, soft capsules and oral administration liquid preparations by adopting the conventional preparation method in pharmaceutics. The Chinese medicinal composition of the invention can be applied to the preparation of medicaments for treating stomachache, dysmenorrheal and abnormal menstruation which are caused by dampness-heat obstruction, and also can be applied to the preparation of medicaments for treating pelvic inflammation, acute and subacute paroxysm of the pelvic inflammation and pelvic inflammation sequelae.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating pelvic inflammatory disease and a preparation method thereof. technical background [0002] Pelvic inflammatory disease (Pelvic Inflammatory Disease, PID) occurs when the female internal genitalia and its surrounding connective tissue and pelvic peritoneum are inflamed. Pelvic inflammatory disease is a common disease in gynecology. Inflammation can be limited to one site, or several sites can be affected at the same time. According to its pathogenic process and clinical manifestations, it can be divided into acute and chronic. [0003] Chronic pelvic inflammatory disease (Chroriic Pelvic Inflammatory Disease, CPID) is often caused by acute pelvic inflammatory disease that has not been completely treated, or the patient's physical fitness is poor, and the course of the disease is protracted, but there may be no ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K36/756A61K36/758A61P15/00
Inventor 谈勇萧伟王振中刘涛尚强孙永城李淼陈凤龙
Owner JIANGSU KANION PHARMA CO LTD
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