Novel secoiridoid compound and application in preparation of anti-inflammatory drug
A compound and mixed eluent technology, applied in the preparation of sugar derivatives, anti-inflammatory agents, drug combinations, etc., can solve problems such as no compounds yet
Inactive Publication Date: 2010-10-13
BEIJING FATAI TIMES PHARMA TECH
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At present, there is no report similar to the chemical structure of the compounds of the present invention and derivatives thereof
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Abstract
The invention relates to a novel secoiridoid compound and application in the preparation of anti-inflammatory drugs. A novel compound is extracted and separated from gentiana straminea, has a chemical structural general formula shown in a formula I and has anti-inflammatory activity. The invention also relates to a use of the compound or pharmaceutically acceptable salts of the compound in the preparation of drugs, in particular to a use in the preparation of anti-inflammatory drugs. The invention also relates to a pharmaceutical composition taking the compound as a main component.
Description
technical field The invention relates to a new split-ring iridoid compound extracted and separated from Gentiana straminea Maxim. and its derivatives. The present invention also relates to the use of the compound or its pharmaceutically acceptable salts in the preparation of medicines, especially the use in the preparation of anti-inflammatory medicines. The present invention also relates to a pharmaceutical composition mainly composed of the compound or its pharmaceutically acceptable salts. In particular, the invention relates to compounds of formula I: Background technique Gentiana is an important traditional Chinese medicine in my country. It was first recorded in "Shen Nong's Materia Medica" and listed as a middle grade. Clinical treatment is used for rheumatic arthralgia, spasm of tendons, joint pain, hot flashes in the afternoon, and malnutrition fever in children. Gentiana macrophylla Pall., Gentiana crassicaulis Duthie., Gentiana dahurica Fisch. , Gentiana str...
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IPC IPC(8): C07H17/04C07H1/08A61K31/7048A61P29/00
Inventor 陈光
Owner BEIJING FATAI TIMES PHARMA TECH
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