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A kind of pharmaceutical composition for treating heart failure and its preparation method and application

A technology of composition and medicine, which is applied in the field of pharmaceutical composition for the treatment of heart failure, can solve the problems of attenuation and efficiency enhancement, compatible use, uncertain parts, etc., and achieve the effect of clear drug effect and low toxicity

Inactive Publication Date: 2011-11-30
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above reports are all large prescription preparations containing aconite and dried ginger, and there is no report on the compatibility of only using aconite and dried ginger, and because the medicinal ingredients in aconite and dried ginger are complex, the parts of the ingredients that exert their medicinal effects are not sure. At present, there is no report on the use of effective parts in combination to achieve attenuation and efficiency enhancement.

Method used

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  • A kind of pharmaceutical composition for treating heart failure and its preparation method and application
  • A kind of pharmaceutical composition for treating heart failure and its preparation method and application
  • A kind of pharmaceutical composition for treating heart failure and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] The preparation method of embodiment 1 medicine of the present invention

[0026] Take 100g of raw aconite and 100g of dried ginger, add 10 times the amount of water to decoct, boil and decoct for 6 hours, pour out the supernatant, filter, then concentrate to the equivalent of 1g aconite per ml, add starch to granulate, add stearic acid Magnesium, pressed into tablets, got tablets.

Embodiment 2

[0027] The preparation of embodiment 2 medicines of the present invention

[0028] Get raw aconite 500g, dry ginger 200g, extract by the method for embodiment 1, granulate, pack into capsule, obtain capsule.

Embodiment 3

[0029] Embodiment 3 preparation of medicine of the present invention

[0030] Get raw aconite 100g, dry ginger 200g, extract by the method for extracting conventional medicinal materials or the method of embodiment 1, granulate, pack into capsules, obtain capsules.

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Abstract

The invention provides a pharmaceutical composition for treating heart failure, which is a medicament prepared from the following raw materials in proportion by weight: 2 parts of total alkaloids of aconite and 1 part of dried ginger extract. The invention also provides the preparation method and application of the pharmaceutical composition. The total alkaloids of aconite are not only the main toxic components of aconite, but also the main effective components of aconite exerting the function of restoring yang and rescuing adversity, and their toxic effects are very closely related. When the total alkaloids of aconite and dried ginger extract are compatible at a ratio of 2:1, they have the effect of attenuating and synergizing, with clear efficacy and low toxicity, which provides a new option for clinical practice.

Description

[0001] This application is a divisional application of the patent application with application number: 200710187765.0. Original application number: 200710187765.0, application date: November 23, 2007, invention name: a pharmaceutical composition for treating heart failure, its preparation method and application. technical field [0002] The invention relates to a pharmaceutical composition for treating heart failure, which belongs to the field of medicines. Background technique [0003] Aconite combined with dried ginger is a frequently used antidote in traditional Chinese medicine in ancient and modern times. Aconite dried ginger decoction was first seen in "Treatise on Febrile Diseases·Taiyang Diseases". Aconite is pungent and warm, and the "Materia Medica Classic Reading" says: "It tastes pungent and warm, and the fire is rapid. It warms the heart and restores the yang, which can invigorate the heart yang. It is omnipresent, so it is the first product of returning to yang...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61P9/04A61K36/714
Inventor 彭成郭力曹小玉曾代文唐劲松余葱葱
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE