Preparation method of traditional Chinese medicinal soft capsules for treating breast diseases and product thereof
A technology for soft capsules and breast diseases, applied in the field of traditional Chinese medicine, can solve the problems of destruction, reduction of drug efficacy, loss of activity, etc., and achieve the effects of improving moisture resistance, easy swallowing, and bioavailability
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[0148] [Example 1] Preparation of soft capsules
[0149] Weigh the raw materials according to the following weights: 1031.25g orange leaves 1031.25g salvia 1031.25g saponins 687.5g Wangbuliuxing 687.5g Chuanmuzi 687.5g Dilong 687.5g
[0150] Weigh according to the prescription except Dilong, Wang Buliu, and other four flavors such as tangerine leaves. Using dynamic continuous countercurrent extraction technology, crush the above medicinal materials and put them into continuous extraction pot, add water to extract for 1 hour, and concentrate the filtrate to relative density It is 1.25~1.30 (85℃), keep it cold and set aside; Dilong and Wang Buliu are extracted twice with 6 times the amount of 70% ethanol at reflux, the first time is 2 hours, the second time is 1 hour, filtered, and the filtrate is combined , Add to the above concentrated solution, adjust the amount of ethanol to 70%, stir evenly, let stand for 24 hours, recover the ethanol and concentrate to a relative density of abo...
Example Embodiment
[0151] [Example 2] Preparation of soft capsule
[0152] Weigh the raw materials according to the following weights: 1031.25g orange leaves 1031.25g salvia 1031.25g saponins 687.5g Wangbuliuxing 687.5g Chuanmuzi 687.5g Dilong 687.5g
[0153] Weigh according to the prescription except Dilong and Wang Buliu, and decoct the other four flavors such as orange leaves with water for 1 hour each time. Combine the decoction, filter, and concentrate the filtrate to a relative density of 1.25-1.30 (85℃). ), let cool and set aside; Dilong and Wang Buliu were extracted twice with 6 times the amount of 70% ethanol under reflux, the first time was 2 hours, the second time was 1 hour, filtered, combined the filtrate, and added to the above concentrated solution, Adjust the amount of ethanol to 70%, stir well, let stand for 48 hours, recover the ethanol and concentrate to a relative density of about 1.25 (50°C), vacuum dry at 60°C, crush to 120-150 mesh, mix well, add 1.28 times soybean oil With 0....
Example Embodiment
[0154] [Example 3] Preparation of soft capsules
[0155] Weigh the ingredients according to the following weights: orange leaves 515.6g salvia 515.6g saponins 343.8g Wangbuliuxing 343.8g Chuanmuzi 343.8g Dilong 343.8g
[0156] Weigh according to the prescription except Dilong, Wang Buliu, and other four flavors such as tangerine leaves. Using dynamic continuous countercurrent extraction technology, crush the above medicinal materials and put them into continuous extraction pot, add water to extract for 1 hour, and concentrate the filtrate to relative density It is 1.25~1.30 (85℃), let it cool and set aside; Dilong and Wang Buliu are extracted twice with 8 times 70% ethanol at reflux, the first time is 2 hours, the second time is 1 hour, filtered, and the filtrate is combined , Add to the above concentrated solution, adjust the amount of ethanol to 70%, stir evenly, let stand for 24 hours, recover the ethanol and concentrate to a relative density of about 1.25 (50°C), vacuum dry at ...
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