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Chinese medicinal composition and preparation method thereof

A composition and technology of traditional Chinese medicine are applied in the field of traditional Chinese medicine composition for the treatment of hypertension, preparation of the traditional Chinese medicine composition, and hyperlipidemia accompanied by sexual dysfunction or lowness, and can solve the problems of slow anti-hyperlipidemia effect and long course of treatment, etc., Achieve the effect of improving sexual function and shortening the latency of erection

Inactive Publication Date: 2012-11-21
THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the above-mentioned traditional Chinese medicine extracts also have good curative effects, the compound composed of the above two traditional Chinese medicines has a slow anti-hyperlipidemia effect and a long course of treatment.

Method used

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  • Chinese medicinal composition and preparation method thereof
  • Chinese medicinal composition and preparation method thereof
  • Chinese medicinal composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] (1) Take 10g of Epimedium, 3g of Semen Cassiae, and 8g of Tribulus terrestris, pulverize and mix, add 14 times of 50% ethanol, heat and reflux to extract 3 times, each time for 0.5h, filter with gauze, concentrate under reduced pressure until there is no alcohol smell, The medicine liquid ratio (crude medicine: water) after decompression concentration is 1: 1.2;

[0020] (2) The extract obtained in step (1) is divided into two alcohol precipitations, the first time is 60% alcohol precipitation for 8h, filtered, and concentrated under reduced pressure until the relative density of the extract is 1.15 at 60°C; the second time is 80% Precipitate with alcohol, filter, and concentrate under reduced pressure until the relative density of the extract is 1.20 at 60°C;

[0021] (3) vacuum-dry the extract obtained in step (2) at 70° C., and pulverize.

[0022] (4) Pulverize the traditional Chinese medicine extract obtained in step (3), add 15% micropowder silica gel, mix evenly,...

Embodiment 2

[0024] (1) Take 10g of Epimedium, 5g of Semen Cassiae, and 10g of Tribulus terrestris, pulverize and mix them, add 12 times of water, decoct 2 times, 2 hours each time, filter with gauze, concentrate under reduced pressure to extract, and concentrate under reduced pressure The ratio of medicine to liquid (crude medicine: water) is 1:1.5;

[0025] (2) The extract obtained in step (1) is divided into two alcohol precipitations, the first time is 60% alcohol precipitation for 8h, filtered, and concentrated under reduced pressure until the relative density of the extract is 1.15 at 60°C; the second time is 80% Precipitate with alcohol, filter, and concentrate under reduced pressure until the relative density of the extract is 1.20 at 60°C;

[0026] (3) vacuum-dry the extract obtained in step (2) at 70° C., and pulverize.

[0027] (4) Pulverize the traditional Chinese medicine extract obtained in step (3), add 15% micropowder silica gel, mix evenly, pass through a 60-mesh sieve, a...

Embodiment 3

[0029] (1) Take 12g of Epimedium and 12g of Tribulus terrestris, crush and mix, add 15 times of water, decoct 3 times, 1 hour each time, filter with gauze; depend on 5g of cassia seed, add 12 times of water after crushing, decoct 2 times , 2 hours each time, filtered with gauze, after the filtrate was mixed with the above-mentioned filtrate, concentrated under reduced pressure to extractum, the ratio of medicinal liquid after concentrated under reduced pressure (crude drug: water) was 1: 1.4;

[0030] (2) The extract obtained in step (1) is divided into two alcohol precipitations, the first time is 60% alcohol precipitation for 8h, filtered, and concentrated under reduced pressure until the relative density of the extract is 1.15 at 60°C; the second time is 80% Precipitate with alcohol, filter, and concentrate under reduced pressure until the relative density of the extract is 1.20 at 60°C;

[0031] (3) vacuum-dry the extract obtained in step (2) at 70° C., and pulverize.

[...

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Abstract

The invention provides a Chinese medicinal composition, which comprises the following Chinese herbal medicines in part by weight: 8 to 12 parts of epimedium herb, 3 to 6 parts of cassia seed and 8 to 12 parts of puncturevine caltrop fruit. Preferably, according to the formula, the Chinese medicinal composition comprises 10 parts of epimedium herb, 5 parts of cassia seed and 10 parts of puncturevine caltrop fruit. The Chinese medicinal composition is prepared into clinically acceptable formulations by adding pharmaceutically acceptable carriers / excipients and has a good curative effect of treating hypertension and hyperlipidemia with sexual functioning inventory or debility.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating hypertension and hyperlipidemia accompanied by hypofunction or hypofunction, and also relates to a preparation method of the traditional Chinese medicine composition. Background technique [0002] In recent years, the phenomenon of "three highs and one low" (high blood pressure, hyperlipidemia, diabetes accompanied by hypofunction or low sexual function) has been increasing among middle-aged and elderly people. Especially "two highs and one low", that is, the incidence rate of high blood pressure and high blood fat accompanied by hypofunction or low sexual function is high. There are two main reasons for this. First, the atherosclerosis and blood hypercoagulation state caused by high blood pressure and high blood lipids make the blood flow into the cavernous sinus of the penis blocked, resulting in less blood sup...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/482A61P9/12A61P3/06A61P15/08
Inventor 张萍肖小河周旭王晶彬任永申
Owner THE FIFTH MEDICAL CENT OF CHINESE PLA GENERAL HOSPITAL
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