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Chinese medicinal gel for treating senile vaginitis and preparation method and application thereof

A technology for vaginitis and traditional Chinese medicine, which is applied in the directions of pharmaceutical formulations, medical preparations with non-active ingredients, active ingredients of hydroxyl compounds, etc., can solve the problems of inappropriate treatment of senile vaginitis, limited treatment scope and insignificant curative effect, etc. First-pass effect of drugs and effects on gastrointestinal stimulation, high-efficiency treatment of diseases, and avoidance of fluctuations in blood drug concentrations

Inactive Publication Date: 2012-02-29
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the commonly used clinically used drugs for the prevention and treatment of senile vaginitis have moderate effects, limited therapeutic range, and insignificant curative effect. produce toxic side effects

Method used

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  • Chinese medicinal gel for treating senile vaginitis and preparation method and application thereof
  • Chinese medicinal gel for treating senile vaginitis and preparation method and application thereof
  • Chinese medicinal gel for treating senile vaginitis and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation Embodiment 1

[0041] Weigh 10g of Baibu, 20g of Bitter Almond, 10g of Azalea, 20g of Yemazhui, 10g of Mutouhui, 20g of Wood Butterfly and 10g of Polygonum cuspidatum, add water twice, decoct, and the amount of water added for the first time is the total weight of the mixed medicinal materials 10 times of the total weight of the mixed medicinal materials, decoct for 2 hours, add water for the second time to 8 times the total weight of the mixed medicinal materials, and decoct for 1 hour. Combine the decoctions, filter, concentrate the filtrate to a relative density of 1.05-1.10, measure at 65°C, add an appropriate amount of ethanol to make the alcohol content reach 75%, in terms of volume fraction, refrigerate at 0-10°C for 24-48 hours, filter, Recover ethanol from the filtrate and concentrate to a relative density of 1.10-1.15, measure at 65°C, dry, and pulverize into dry extract powder; weigh 3 g of borneol in proportion, pulverize into fine powder, and pass through a 100-mesh sieve; Add 1...

preparation Embodiment 2

[0043]Weigh 15g of Baibu, 15g of Bitter Almond, 15g of Azalea, 15g of Yemazhui, 15g of Mutouhui, 15g of Wood Butterfly and 15g of Polygonum cuspidatum, add water twice, decoct, the amount of water added for the first time is the total weight of the mixed medicinal materials 10 times of the total weight of the mixed medicinal materials, decocting for 3 hours, and adding water for the second time is 8 times the total weight of the mixed medicinal materials, decocting for 2 hours. Combine the decoctions, filter, concentrate the filtrate to a relative density of 1.05-1.10, measure at 65°C, add an appropriate amount of ethanol to make the alcohol content reach 75%, in terms of volume fraction, refrigerate at 0-10°C for 24-48 hours, filter, Recover ethanol from the filtrate and concentrate to a relative density of 1.10-1.15, measure at 65°C, dry, and pulverize into dry extract powder; weigh 2 g of borneol in proportion, pulverize into fine powder, and pass through a 100-mesh sieve; ...

preparation Embodiment 3

[0045] Weigh 20g of Baibu, 10g of Bitter Almond, 20g of Azalea, 10g of Yemazhui, 20g of Mutouhui, 10g of Wood Butterfly and 20g of Polygonum cuspidatum, add water twice, decoct, the amount of water added for the first time is the total weight of the mixed medicinal materials 10 times of the total weight of the mixed medicinal materials, decoct for 2 hours, add water for the second time to 8 times the total weight of the mixed medicinal materials, and decoct for 1 hour. Combine the decoctions, filter, concentrate the filtrate to a relative density of 1.05-1.10, measure at 65°C, add an appropriate amount of ethanol to make the alcohol content reach 75%, in terms of volume fraction, refrigerate at 0-10°C for 24-48 hours, filter, Recover ethanol from the filtrate and concentrate to a relative density of 1.10-1.15, measure at 65°C, dry, and pulverize into a dry extract powder; weigh 1 g of borneol in proportion, pulverize it into a fine powder, and pass through a 100-mesh sieve; Ad...

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Abstract

The invention provides a Chinese medicine composition to achieve the purpose of treating senile vaginitis through dispelling wind, arresting itching, removing dampness, and destroying parasites. In order to achieve the purpose, the following technical scheme is adopted: active components contained in the Chinese medicine composition are prepared by the following raw materials in parts by weight: 10-20 parts of radix stemonae, 10-20 parts of semen armeniacae amarae, 10-20 parts of chinaberry seeds, 10-20 parts of lindley eupatorium, 10-20 parts of patrinia heterophylla, 10-20 parts of oroxylumindicum, 10-20 parts of polygonum cuspidatum, 1-3 parts of borneol, 1-3 parts of carbomer, 50-100 parts of glycerol, 1-3 parts of triethanolamine and 425-475 parts of distilled water; and the raw materials are prepared into gel by adopting a corresponding preparation method. The Chinese medicine composition has the functions of dispelling wind, arresting itching, removing dampness, and destroyingparasites, and can be used for treating the senile vaginitis.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition, preparation method and application for treating senile vaginitis. Background technique [0002] Senile vaginitis (SV), also known as atrophic vaginitis, occurs mostly in postmenopausal elderly women, and is a common clinical senile gynecological disease with a high recurrence rate. The incidence rate of senile vaginitis reported in China is 30%-58.6%, and it is as high as 98.5% in foreign reports. According to reports, reproductive tract infection accounts for 32.2% of common gynecological diseases in postmenopausal women, and senile vaginitis accounts for 12.8% of them. With the development of society, my country has entered an aging society, and the number of patients with senile vaginitis continues to increase, and the degree of disease continues to increase, which seriously affects the quality of l...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K47/32A61K31/045
Inventor 严令耕刘学华潘林梅陈军霞卞凌倪荷芳
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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