Chitosan cervix uteri anti-microbial membrane and preparation method thereof
A technology of antibacterial film and chitosan, which is applied in the field of pharmaceutical preparations containing chitin, to achieve the effects of fast natural degradation, good adhesion and softness, and avoid damage
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[0023] Get chitosan iodine 20g, polysorbate-20 60g, acetic acid 10g, hydroxypropyl methylcellulose 10g, gelatin 50g, glycerin 50g, and purified water 800mL, altogether 1000g material;
[0024] Add gelatin into a stirring container filled with purified water, set the temperature of the water bath at 60°C to heat, keep stirring for about 4 hours to dissolve; then add hydroxypropyl methylcellulose and continue stirring for about 2 hours to dissolve; then add the prescribed amount Stir the glycerin to mix evenly; after that, stir to cool the material to about 30°C, and mix it with the prepared chitosan-iodine solution evenly to inject the film; finally, after the film is injected, put the mold into a freeze dryer and freeze at -50°C After freezing for 4 hours, remove the cover, continue to freeze for 2 hours, and enter into freeze-vacuum drying; after freeze-vacuum drying, take it out from the machine in a sterile state, put it into boxes, add outer packaging, and sterilize to obta...
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