Middle/low concentration positive quality control liquid for urine analysis

A positive quality control and urine analysis technology, applied in the field of quality control solution, can solve the problems of difficult preparation of magnesium acetoacetate, limited sources of quality control substances, high risk of biological contamination, etc., so as to reduce mutual interference and reduce biological risks. , the effect of low production cost

Active Publication Date: 2013-07-31
URIT MEDICAL ELECTRONICS CO LTD
View PDF5 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the quality control materials used in the above-mentioned quality control solution are not widely sourced, expensive, and have a high risk of biological contamination. For example, human serum albumin and human red blood cells in the invention are derived from the human body; magnesium acetoacetate is difficult to prepare and expensive. more expensive

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Middle/low concentration positive quality control liquid for urine analysis
  • Middle/low concentration positive quality control liquid for urine analysis
  • Middle/low concentration positive quality control liquid for urine analysis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0123] Borate buffer solution with pH 5.7, 60mmol / L;

[0124] Tween-20, 40mmol / L;

[0125] Trehalose, 50mmol / L;

[0126] K30, 40mmol / L;

[0127] Glucose item: anhydrous glucose, 500mg / L;

[0128] Albumin item: bovine serum albumin, 300mg / L;

[0129] Occult blood items: bovine hemoglobin, 1mg / L;

[0130] White blood cell items: esterase, 12mg / L;

[0131] Ketone body item: acetone, 150mg / L;

[0132] Bilirubin item: 1-naphthylamine hydrochloride, 12mg / L;

[0133] Urobiliol original item: 2,5-dimethylpyrrole, 15mg / L;

[0134] Nitrite item: nitrite, 12mg / L;

[0135] Creatinine item: creatinine, 500mg / L;

[0136] Urinary calcium items: anhydrous calcium chloride, 500mg / L.

[0137] The positive quality control solution of the present invention is prepared by conventional methods. The prepared quality control solution is colorless and transparent.

[0138] In order to illustrate the effect of the quality control solution of the present invention, a comparative experiment w...

Embodiment 2

[0148] Borate buffer solution with a pH of 7.1, 135mmol / L;

[0149] Tween-20, 100mmol / L;

[0150] Trehalose, 130mmol / L;

[0151] K30, 160mmol / L;

[0152] Anhydrous glucose, 990mg / L;

[0153] Bovine serum albumin, 800mg / L;

[0154] Bovine hemoglobin, 3mg / L;

[0155] Esterase, 18mg / L;

[0156] Ethyl acetoacetate, 150mg / L;

[0157] 1-naphthylamine hydrochloride, 20mg / L;

[0158] 2,3-Dimethylindole, 40mg / L;

[0159] Nitrite, 20mg / L;

[0160] Creatinine, 1000mg / L;

[0161] Ascorbic acid, 250mg / L;

[0162] Anhydrous calcium chloride, 1500mg / L.

Embodiment 3

[0164] PH is the glycine-tris buffer solution of 6.0, 60mmol / L;

[0165] Brij35, 60mmol / L;

[0166] Lactose, 80mmol / L;

[0167] Gelatin, 80mmol / L;

[0168] Anhydrous glucose, 800mg / L;

[0169] Bovine serum albumin, 600mg / L;

[0170] Bovine hemoglobin, 2mg / L;

[0171] Esterase, 15mg / L;

[0172] Sodium ethyl acetoacetate, 150mg / L;

[0173] Direct bilirubin, 40mg / L;

[0174] Pyrrole, 40mg / L;

[0175] Nitrite, 10mg / L;

[0176] Creatinine, 1000mg / L;

[0177] Anhydrous calcium chloride, 1000mg / L.

[0178] In order to illustrate the stability effect of the quality control solution of the present invention, embodiment 3 is compared with 3 comparison groups:

[0179] Comparative group 1: Briji-35, lactose, and gelatin were not added in Example 3;

[0180] Contrast group 2: do not add lactose, gelatin in embodiment 3;

[0181] Comparative group 3: No gelatin was added in Example 3.

[0182] Each comparison group was prepared at the same time as that of Example 1, and store...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a middle / low concentration positive quality control liquid for urine analysis. The positive quality control liquid comprises a buffer solution with a pH value of 4.5 to 8.5 and a concentration of 20 to 200 mmol / L, a surfactant with the concentration of 20 to 200 mmol / L, a carbohydrate protectant with the concentration of 20 to 200 mmol / L, a protein protectant with the concentration of 20 to 200 mmol / L, anhydrous glucose with the concentration of 300 to 990 mg / L, bovine serum albumin with the concentration of 100 to 1000 mg / L, bovine hemoglobin with the concentration of0.6 to 5 mg / L, esterase with the concentration of 2 to 20 mg / L, acetone or lithium acetoacetate or sodium ethyl acetoacetate or ethyl acetoacetate with the concentration of 50 to 900 mg / L, and a direct bilirubin or naphthylamine salt with the concentration of 3 to 40 mg / L. Quality control objects of corresponding projects can be added as needed. Compared with the prior art, the quality control liquid has the advantages of good stability, high sensitivity, less toxicity of each component, wide source and low production cost.

Description

technical field [0001] The invention relates to a quality control solution for quality control of a urine chemical analysis system in urine chemical analysis testing technology, in particular to a medium-low concentration positive quality control solution for urine analysis. Background technique [0002] In the existing urine (dry chemistry) analysis test, the quality control fluid is used clinically to control the quality of the working quality of the urine chemical analysis system. Generally, the test results are divided into N (normal, negative), ± (questionable state), +1 (positive), +2 (positive), +3 (positive), +4 (positive), +5 (positive) and so on. The existing quality control solution is divided into negative quality control solution (contains ultra-low concentration quality control substance or does not contain corresponding quality control substance), high positive quality control solution or high concentration quality control solution (contains higher concentrati...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/50
Inventor 冼庆勇刘云鹏
Owner URIT MEDICAL ELECTRONICS CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap