Complex vitamin molecule microemulsion and preparation method thereof

A molecular microemulsion and multivitamin technology, applied in the field of pharmaceutical preparations, can solve the problems of unstable product quality, secondary coagulation and stratification, and easy to darken color when exposed to light, achieving good thermodynamic stability and improved bioavailability. , the effect of uniform distribution

Inactive Publication Date: 2012-01-25
FOSHAN STANDARD BIO TECH
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  • Summary
  • Abstract
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Problems solved by technology

The problems of this preparation method are high energy consumption, unstable product quality, easy occurre...

Method used

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Embodiment Construction

[0022] A kind of compound vitamin molecular microemulsion of the present invention, it comprises following component (by weight ratio), fat-soluble vitamin (2.0-10.0) g, solubilizer (37-100) g, antioxidant amount, emulsifier (7.5- 20) g, co-emulsifier (80-200) g, water-soluble vitamin (10.0-100.0) g, various amino acids (10-50) g ​​and purified water (550-750) ml. Fat-soluble vitamins include vitamin A, vitamin D 3 , Vitamin E, add 50-70 parts of solubilizer for every 10 parts of fat-soluble vitamins. The solubilizer and emulsifier are one or more combinations of polyethylene hydrogenated castor oil, fatty alcohol polyoxyethylene ether, Tween-80, Tween-20, Span-80, and poloxamer. The co-emulsifier is one or more combinations of n-butanol, propylene glycol, and glycerin. Antioxidants are tert-butylhydroxyanisole, di-tert-butylmethylphenol, tert-butylhydroquinone, methylparaben, methylparaben, ethylparaben, propylparaben One or more combinations of esters, butyl p-hydroxybenz...

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Abstract

The invention discloses a complex vitamin molecule microemulsion and a preparation method thereof. In terms of the formula, the complex vitamin molecule microemulsion comprises the following components (in weight ratio): 2.0-10.0g of fat soluble vitamin, 37-100g of solubilizer, antioxidant, 7.5-20g of emulsion, 80-200g of assistant emulsifier, 10.0-100.0g of water soluble vitamin, 10-50g of multiple amino acids and 550-750ml of purified water. The complex vitamin molecule microemulsion disclosed by the invention has the advantages of high stability, high solution, high absorption, high nutrition and good promotional value.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a method for preparing liquid additive premixed feed. Background technique [0002] At present, the multivitamin products on the market are mainly solid preparations, which are easy to be graded during storage and transportation, and are easily affected by light, damp heat, etc., resulting in oxidation loss; high temperature, high humidity, high pressure, mechanical friction, etc. during production can cause vitamin loss. It is often necessary to add several times the nutritional requirements of animals, resulting in waste; when using multidimensional premixes, it usually needs to be fed with mixing materials, which is not only labor-intensive, but also prone to problems of uneven mixing. When diluted with drinking water, the liquid becomes turbid, milky or misty in appearance, uneven distribution, animal intake cannot be guaranteed, poor bioavailability, bloc...

Claims

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Application Information

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IPC IPC(8): A23K1/16A23K20/10A23K20/105A23K20/142A23K20/174
Inventor 谭志坚
Owner FOSHAN STANDARD BIO TECH
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