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Veterinary compound Chinese-western drug composition for defervescing and diminishing inflammation

A composition and drug technology, applied in the field of traditional Chinese veterinary medicine, can solve the problems of short action time and short half-life, and achieve long-lasting effects, less toxic and side effects, and rapid curative effect

Active Publication Date: 2012-03-21
BEIJING DABEINONG ANIMAL HEALTH TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the long-term widespread use, the tolerance has been continuously improved, and its own half-life is very short, t 1 / 2 About 1 to 4 hours, the action time is very short

Method used

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  • Veterinary compound Chinese-western drug composition for defervescing and diminishing inflammation
  • Veterinary compound Chinese-western drug composition for defervescing and diminishing inflammation
  • Veterinary compound Chinese-western drug composition for defervescing and diminishing inflammation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The drug in this example is prepared from the following raw materials: Bupleurum 3000g, Guizhi 3000g, Licorice 1000g, Scutellaria baicalensis 1500g, Gardenia 1500g, Analgin 2500g.

[0032] The preparation process is as follows: 1) Puple bupleurum, cassia twig and gardenia are crushed separately, mixed, added to a volatile oil extractor, and water more than 4 times the total weight of the medicinal materials is added, soaked for 12 hours, boiled and refluxed for more than 6 hours to extract the volatile oil, and set aside; 2) Add licorice to the medicinal residue and medicinal liquid mixture after extracting the volatile oil in 1), add water to decoct 3 times, the amount of decocting water each time is more than 4 times the total weight of the medicinal materials, combine the decoctions, and concentrate to the original 0.5 times the amount of medicinal materials, alcohol precipitation twice, adding ethanol to make the alcohol content reach 60% and 75% respectively. Recov...

Embodiment 2

[0034] The drug in this example is prepared from the following raw materials: Bupleurum bupleuri 1000g, cassia twig 500g, licorice 300g, scutellaria baicalensis 500g, gardenia 500g, analgin 1000g.

[0035] Prepare the oral liquid according to the method for preparing the injection in Example 1.

Embodiment 3

[0037] The drug of this example is prepared from the following raw materials: Bupleurum 6000g, Guizhi 6000g, Licorice 5000g, Scutellaria baicalensis 6000g, Gardenia 6000g, Analgin 3500g.

[0038] The preparation process is as follows: 1) Crush Bupleurum, Cinnamon Twig, and Gardenia respectively, mix them, put them into a volatile oil extractor, add water more than 4 times the total weight of the medicinal materials, soak for 12 hours, and extract the volatile oil for 8 hours; add the excipient β- Cyclodextrin, prepared into cyclodextrin inclusion compound, for later use; 2) add licorice to the mixture of medicinal residues and medicinal liquid after extracting volatile oil, add water to decoct twice, the amount of twice decocting water is the total weight of medicinal materials More than 4 times; combined decoction liquid, concentrated to 0.5 times of the total amount of the original medicinal materials, added ethanol to make the alcohol content reach 60%, precipitated for 12 h...

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PUM

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Abstract

The invention relates to a veterinary quick-acting compound Chinese-western drug composition used for defervescing and diminishing inflammation, and belongs to the field of traditional Chinese veterinary medicine. The drug composition provided by the invention comprises the components including Bupleurum, cassia twig, glycyrrhiza, baical skullcap root, cape jasmine fruit and analgin. The composition can be manufactured into injection, oral liquid, granular formulation, powder or the like. The compound Chinese-western drug composition provided by the invention has a synergistic effect, has a better effect on defervescing and diminishing inflammation than that of prescribed preparations of chemical drug and TCM (Traditional Chinese Medicine) preparations, achieves curative effect quickly, can act for a long time, and has low cost of drug material and better market prospect.

Description

technical field [0001] The invention relates to a veterinary Chinese and Western compound antipyretic and anti-inflammatory pharmaceutical composition, which belongs to the field of traditional Chinese veterinary medicine. Background technique [0002] When livestock and poultry are infected by pathogens such as bacteria, viruses, mycoplasma, and parasites, most of them are accompanied by clinical symptoms such as high fever, pain, and inflammation, such as common porcine circovirus disease, porcine blue ear disease, swine fever, swine fever, etc. Influenza, porcine pseudorabies, porcine contagious pleuropneumonia, porcine erysipelas, porcine lung disease, porcine toxoplasmosis, porcine Eperythrozoonosis, bovine pneumonia, bovine epidemic fever, Newcastle disease, avian influenza, fowl cholera, duck plague, rabbit Plague and so on. The above-mentioned infectious diseases of livestock and poultry are prevalent all over the world, causing the death of livestock and poultry, t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/744A61P29/00A61K31/4152
Inventor 邓利斌莫云刘澜贠桂玲杜继红王海良
Owner BEIJING DABEINONG ANIMAL HEALTH TECH
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