Chinese medicinal composition for treating middle-aged and senile eye disease and preparation method thereof

A technology for eye diseases and compositions, which is applied in the field of traditional Chinese medicine composition and its preparation for the treatment of middle-aged and elderly eye diseases, and can solve problems such as difficult implementation, unsatisfactory effects of Chinese patent medicines, and unsatisfactory therapeutic effects.

Active Publication Date: 2012-04-18
XIAN BEILIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002]Elderly eye disease is a common and frequently-occurring disease, which seriously affects people's daily life; Photophobia, blurred vision, glaucoma, cataract in the early and middle stages; there are many Chinese patent medicines for the treatment of this disease, but most of the treatment effects are not ideal
Prior Art Patent Retrieval: On September 11, 2002, the Chinese Patent Gazette disclosed a patent application titled "Nano Fuming Preparation Drug and Its Preparation Method" with the publication number CN 1368247A. We conducted an in-depth analysis of the medicinal material Betel Nut and concluded that the content disclosed in this patent is unscientific and difficult to implement
1. On November 10, 2004, the Chinese Patent Gazette disclosed a patent application entitled "A Chinese Medicine for Treating Middle-aged and Elderly Eye Diseases and Its Preparation Method" with the publication number CN 1544072A; 2. On January 17, 2007, China The patent bulletin discloses a patent application titled "Preparation Method of Fuming Mixture and Its Testing Method" with the publication number CN 1895552A; the weight ratios of the raw materials of each medicine in the above two patents are: 1g of antelope horn and 40g of Tribulus terrestris , Horsetail 25g, Chrysanthemum 50g, Plantago 25g, Prunella vulgaris 25g, Cassia 40g, Ginseng 15g, Dogwood (made) 25g, Dendrobium 40g, Lycium barbarum 40g, Cuscuta 25g, Ligustrum lucidum 25g, Shicasia 50g, Coptis chinensis 10g, Gujingcao 25g, Guan Mutong 25g, Rehmannia glutinosa 25g, Chinese yam 25g, Alisma 10g, Poria cocos 25g, Moutan cortex 25g, Rehmannia glutinosa 25g, betel nut 25g; The effect of the patented medicine is not ideal; in recent years, on the basis of this formula, we have explored through a large number of experiments, and unexpectedly found that after reducing the dosage of chrysanthemum and increasing the dosage of coptis and rehmannia glutinosa, its clinical medicine The effect of the pharmacokinetic experiment is significantly improved without any side effects; we make tablets, capsules and granules according to the conventional process

Method used

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  • Chinese medicinal composition for treating middle-aged and senile eye disease and preparation method thereof
  • Chinese medicinal composition for treating middle-aged and senile eye disease and preparation method thereof
  • Chinese medicinal composition for treating middle-aged and senile eye disease and preparation method thereof

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Experimental program
Comparison scheme
Effect test

preparation example Construction

[0037] 1. Preparation of experimental drugs:

[0038] 1. Raw materials:

[0039] Group a is the group of the present invention: Antelope horn 1g, Tribulus terrestris 40g, Equisetum 25g, Chrysanthemum 25g, Plantago 25g, Prunella vulgaris 25g, Cassia 40g, Ginseng 15g, Cornus officinalis (manufactured) 25g, Dendrobium 40g, Wolfberry 40g, Dodder 25g, Ligustrum lucidum 25g, Cassia 50g, Coptis 50g, Gujingcao 25g, Akebia 25g, Rehmannia glutinosa 75g, Chinese yam 25g, Alisma 10g, Poria cocos 25g, Moutan cortex 25g, Rehmannia glutinosa 25g, Betel nut 25g.

[0040] original invention group : Antelope horn 1g, Tribulus terrestris 40g, Equisetum 25g, Chrysanthemum 50g, Plantago seed 25g, Prunella vulgaris 25g, Cassia seed 40g, Ginseng 15g, Dogwood (manufactured) 25g, Dendrobium 40g, Lycium barbarum 40g, Dodder seed 25g, Ligustrum lucidum 25g, Cassia 50g, Coptis 10g, Gujingcao 25g, Akebia 25g, Rehmannia glutinosa 25g, Chinese yam 25g, Alisma 10g, Poria cocos 25g, Moutan cortex 25g, ...

Embodiment 1

[0126] The preparation of tablet of the present invention:

[0127] prescription:

[0128] Antelope Horn 1g Tribulus terrestris 40g Horsetail 25g

[0129]Chrysanthemum 25g Psyllium 25g Prunella vulgaris 25g

[0130] Cassia seed 40g Ginseng 15g Cornus officinalis (made) 25g

[0131] Dendrobium 40g Wolfberry 40g Cuscuta 25g

[0132] Ligustrum 25g Cassia 50g Coptis 50g

[0133] Gujingcao 25g Akebia 25g Rehmannia glutinosa 75g

[0134] Yam 25g Alisma 10g Poria 25g

[0135] Peony bark 25g Rehmannia glutinosa 25g Betel nut 25g.

[0136] Preparation:

[0137] The above twenty-four flavors, quinoa, horsetail, chrysanthemum, plantain seed, cassia seed, dogwood, ginseng, and dendrobium are crushed into fine powder, sieved, and mixed; antelope horn is crushed into fine powder, and mixed with the above fine powder; The other fifteen flavors such as medlar, add water and decoct twice, each time for 2 hours, filter the decoction, combine the filtrate, concentrate under reduced press...

Embodiment 2

[0139] The preparation of capsule of the present invention:

[0140] prescription:

[0141] Antelope Horn 1g Tribulus terrestris 40g Horsetail 25g

[0142] Chrysanthemum 25g Psyllium 25g Prunella vulgaris 25g

[0143] Cassia seed 40g Ginseng 15g Cornus officinalis (made) 25g

[0144] Dendrobium 40g Wolfberry 40g Cuscuta 25g

[0145] Ligustrum 25g Cassia 50g Coptis 50g

[0146] Gujingcao 25g Akebia 25g Rehmannia glutinosa 75g

[0147] Yam 25g Alisma 10g Poria 25g

[0148] Peony bark 25g Rehmannia glutinosa 25g Betel nut 25g.

[0149] Preparation:

[0150] The above twenty-four flavors, quinoa, horsetail, chrysanthemum, plantain seed, cassia seed, dogwood, ginseng, and dendrobium are crushed into fine powder, sieved, and mixed; antelope horn is crushed into fine powder, and mixed with the above fine powder; The other fifteen flavors such as medlar, add water and decoct twice, each time for 2 hours, filter the decoction, combine the filtrate, concentrate under reduced pre...

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Abstract

The invention relates to a Chinese medicinal composition for treating a middle-aged and senile eye disease and a preparation method thereof. The Chinese medicinal composition consists of the following materials by weight: 1 g of antelope horn, 40 g of caltrop, 25 g of scouring rush, 25 g of chrysanthemum, 25 g of plantain seed, 25 g of selfheal spike, 40 g of sicklesenna seed, 15 g of ginseng, 25g of cornus (processed), 40 g of dendrobe, 40 g of meldar, 25 g of dodder, 25 g of glossy privet fruit, 50 g of shell of abalone or sea-ear, 50 g of coptis root, 25 g of pipewort, 25 g of akebia stem, 75 g of prepared rhizome of rehmannia, 25 g of yam, 10 g of rhizoma alismatis, 25 g of tuckahoe, 25 g of tree peony bark, 25 g of rehmannia and 25 g of areca nut. The clinical pharmacodynamic test effect is obviously improved; and the Chinese medicinal composition has an obviously enhanced curative effect on fundus hemorrhage caused by yin deficiency, liver-yang hyperactivity and collateral injury due to heat, and has obviously improved clinical pharmacodynamic test effect, high bioavailability and no any toxic or side effect.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and in particular relates to a traditional Chinese medicine composition for treating middle-aged and elderly eye diseases and a preparation method thereof. technical background [0002] Senile eye disease is a common and frequently-occurring disease, which seriously affects people's daily life; the common ones are: photophobia caused by liver and kidney yin deficiency, blurred vision, glaucoma, early and middle stage cataracts; There are many Chinese patent medicines for the treatment of this disease, but most of the therapeutic effects are not ideal enough. Prior Art Patent Retrieval: On September 11, 2002, the Chinese Patent Gazette published a patent application titled "Nano Fuming Preparation Drug and Its Preparation Method" with the publication number CN 1368247A. Betel nut” medicinal material, we conducted an in-depth analysis on it and believed that the content disclosed in this patent i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61P27/02A61K35/32A61K35/56A61K35/618
Inventor 曲风衍
Owner XIAN BEILIN PHARMA
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