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Chinese medicinal preparation for treating vaginitis and preparation method thereof

A technology of traditional Chinese medicine preparations and vaginitis, applied in anti-inflammatory agents, pharmaceutical formulas, non-central analgesics, etc., can solve problems such as inconvenient use, difficult to completely cure diseases, and inability to maintain quick-acting and long-acting effects

Active Publication Date: 2012-07-04
陕西步长高新制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

During the actual experimental research, we found that the single herb of Hawthorn has unexpected therapeutic effects on vaginitis caused by various reasons. Therefore, we applied for the application number 03139655.0 on June 26, 2003 The invention patent was obtained after that, and the patent document is mainly protected from the aspects of prescription ratio and lotion. However, because the vaginal lotion formulation itself belongs to local application, it is inconvenient to use and the loss of liquid medicine is large, so it cannot be maintained. Disadvantages such as quick-acting, long-acting, and difficult to completely cure the disease, which lead to its influence on the promotion and use of the drug itself to a certain extent

Method used

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  • Chinese medicinal preparation for treating vaginitis and preparation method thereof
  • Chinese medicinal preparation for treating vaginitis and preparation method thereof
  • Chinese medicinal preparation for treating vaginitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0088] (1) Take 1170g of hawthorn core, crush it into coarse particles, add 70% ethanol with a weight ratio of 10 times the amount of the medicinal material, heat and reflux extract twice, each time for 1.5h, filter, combine the filtrate, and keep the medicinal solution; Add water in an amount 8 times the weight ratio of the medicinal material, heat and decoct to extract twice, each time for 1 hour, filter, combine the filtrate, and keep the water for future use;

[0089] (2) Add ethanol to the water solution in the above (1) to make the alcohol content reach 70%, refrigerate for 24 hours, and centrifuge at 2000r / min. After the centrifugate is combined with the ethanol solution in (1), the ethanol is recovered under reduced pressure and decompressed. Concentrated and dried, crushed into dry cream powder, set aside;

[0090] (3) Select the matrix as polyethylene glycol 2000: polyethylene glycol 4000: polyethylene glycol 6000=20%: 50%: 30%, after heating and melting, add co-solv...

Embodiment 2

[0092] (1) Take 1170g of hawthorn core, crush it into coarse particles, add 8 times the weight ratio of the medicinal material, and extract 60% ethanol under reflux for 3 times, each time for 1h, filter, combine the filtrate, and keep the medicinal solution; The water whose weight ratio is 10 times that of the medicinal materials is heated and decocted to extract once, each time for 2 hours, filtered, and the filtrate is combined, and the water is retained for use;

[0093] (2) Add ethanol to the aqueous solution in the above (1) to make the alcohol content reach 80%, refrigerate for 36 hours, and centrifuge at 1000r / min. After the centrifugate is combined with the ethanol solution in (1), the ethanol is recovered under reduced pressure and decompressed. Concentrated and dried, crushed into dry cream powder, set aside;

[0094] (3) Select the matrix as polyethylene glycol 2000: polyethylene glycol 4000: polyethylene glycol 6000=20%: 50%: 30%, after heating and melting, add co-...

Embodiment 3

[0096] (1) Take 1170g of hawthorn core, crush it into coarse particles, add 90% ethanol with a weight ratio of 12 times to the medicinal material, heat and reflux extraction once, each time for 2 hours, filter, combine the filtrate, and keep the medicinal solution; Heat and decoct 3 times, 1.5 hours each time, filter, combine the filtrate, and keep the water for future use;

[0097] (2) Add ethanol to the water solution in the above (1) to make the alcohol content reach 60%, refrigerate for 12 hours, and centrifuge at 3000r / min. After the centrifugate is combined with the ethanol solution in (1), the ethanol is recovered under reduced pressure and decompressed. Concentrated and dried, crushed into dry cream powder, set aside;

[0098] (3) Select the matrix as polyethylene glycol 2000: polyethylene glycol 4000: polyethylene glycol 6000=20%: 50%: 30%, after heating and melting, add co-solvent propylene glycol and the dry mixture obtained in (2) Cream powder, stir evenly, use si...

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Abstract

The invention relates to a Chinese medicinal preparation for treating vaginitis and a preparation method thereof. The Chinese medicinal preparation is prepared by extracting and purifying hawthorn cores serving as a medicinal raw material according to a certain process and then mixing with pharmaceutically acceptable auxiliary materials. The Chinese medicinal preparation has the characteristics of simplicity and feasibility in preparation process, safety, effectiveness and remarkable pharmacological effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation for treating vaginitis and a preparation method thereof, belonging to the technical field of medical preparations. Background technique [0002] Vaginitis is a common and frequently-occurring disease in women's reproductive system inflammation. The main symptoms are increased leukorrhea, pruritus vulvae or accompanied by scorching heat in the vulva, which belongs to the scope of leukorrhea and pruritus vulvae in the motherland's medicine. The etiology is mostly negligence of hygiene, infection of vaginal worms, or damp-heat betting, accumulation of stagnation and worms, or spleen deficiency and damp resistance, dampness and turbidity overflowing the lower energizer, hurting the two veins of the kidney, or liver and kidney yin deficiency, dryness and wind, or Stagnation of heart and liver qi, long-term fire of stagnation caused by disturbing the meridians. Modern Western medicine belie...

Claims

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Application Information

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IPC IPC(8): A61K36/734A61K9/20A61P15/02A61P31/04A61P31/10A61P33/02A61P17/04A61P29/00A61K131/00
Inventor 赵涛卢露谢伟
Owner 陕西步长高新制药有限公司
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