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Chinese medicinal formulation for treating diabetes and preparation method of same

A technology for traditional Chinese medicine preparations and diabetes, applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and pill delivery, etc., can solve problems such as inability to completely cure, eccentric behavior, and slow thinking, and achieve outstanding pharmacological activity, ensure stability, The effect of improving the extraction rate

Inactive Publication Date: 2012-07-04
陕西步长高新制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Common western medicines that can be used include insulin injection and oral hypoglycemic drugs such as Jiatangning, Jiangtangling, glibenclamide, and chlorpropamide, which can only temporarily improve the pathological symptoms, but cannot completely cure them. Side effects, mainly manifested as slow thinking, blurred vision, restlessness, eccentric behavior, convulsions, coma, etc.

Method used

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  • Chinese medicinal formulation for treating diabetes and preparation method of same
  • Chinese medicinal formulation for treating diabetes and preparation method of same
  • Chinese medicinal formulation for treating diabetes and preparation method of same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0081] A. Composition of raw materials: 180g heterophylla, 180g salvia, 54g coptis, 180g astragalus, 180g gynostemma, 180g yam, 120g atractylodes, 54g scrophulariae, 18g leech, 120g mallow fruit, 120g kudzu root;

[0082] B. Preparation process: the above-mentioned 11 Chinese herbal medicines in A are operated according to the following steps:

[0083] (1) After taking the leeches and pulverizing them, soak and extract with ethanol with a concentration of 70%, 18 times the weight ratio of medicinal materials, and 50° C. for 24 hours, filter, and retain the ethanol solution;

[0084] (2) Take Atractylodes atractylodis, add 10 times the weight ratio of the medicinal material to soak in water, use steam distillation to extract the volatile oil for 4 hours, collect the volatile oil, and use 4 times the amount of β-cyclodextrin to clathrate it for later use, after distillation The water is retained;

[0085] (3) Take Coptidis rhizome, add 10 times the weight ratio of the medicinal...

Embodiment 2

[0090] A. Composition of raw materials: 180g heterophylla, 180g salvia, 54g coptis, 180g astragalus, 180g gynostemma, 180g yam, 120g atractylodes, 54g scrophulariae, 18g leech, 120g mallow fruit, 120g kudzu root;

[0091] B. Preparation process: the above-mentioned 11 Chinese herbal medicines in A are operated according to the following steps:

[0092] (1) After the leech is taken and pulverized, it is soaked and extracted with ethanol with a concentration of 60%, 20 times the weight ratio of the medicinal material, and 40° C. for 12 hours, filtered, and the ethanol solution is retained for use;

[0093] (2) Take Atractylodes atractylodis, add 8 times the weight ratio of the medicinal material to soak in water, use steam distillation to extract the volatile oil for 6 hours, collect the volatile oil, and wrap it with 2 times the amount of β-cyclodextrin for later use, after distillation The water is retained;

[0094] (3) Take Coptidis Rhizoma, add 12 times the weight ratio of...

Embodiment 3

[0099] A. Composition of raw materials: 180g heterophylla, 180g salvia, 54g coptis, 180g astragalus, 180g gynostemma, 180g yam, 120g atractylodes, 54g scrophulariae, 18g leech, 120g mallow fruit, 120g kudzu root;

[0100] B. Preparation process: the above-mentioned 11 Chinese herbal medicines in A are operated according to the following steps:

[0101] (1) After taking the leech and pulverizing it, soak and extract it with ethanol with a concentration of 90%, 15 times the weight ratio of the medicinal material, and 60° C. for 36 hours, and filter the ethanol solution for use;

[0102] (2) Take Atractylodes atractylodis, add 12 times the weight ratio of the medicinal material to soak in water, use steam distillation to extract the volatile oil for 2 hours, collect the volatile oil, and wrap it with 6 times the amount of β-cyclodextrin for later use, after distillation The water is retained;

[0103] (3) Take Coptidis Rhizoma, add 8 times the weight ratio of the medicinal mater...

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Abstract

The invention relates to a Chinese medicinal formulation for treating diabetes and a preparation method of the Chinese medicinal formulation. The Chinese medicinal formulation is prepared from the following raw materials in parts by weight: 180 of Radix Pseudostellariae, 180 of Radix Salviae Miltiorrhizae, 54 of Rhizoma Coptidis, 180 of Astragalus membranaceus, 180 of Gynostemma pentaphyllum, 180 of Dioscorea opposita, 120 of Rhizome Atractylodis, 54 of Radix Scrophularia, 18 of Hirudo, 120 of Malva verticillata fruit and 120 of Radix Puerariae. The preparation method comprises the following steps: performing extraction and purification by a certain process and mixing with pharmaceutically-acceptable adjuvant materials. The Chinese medicinal formulation for treating diabetes has the characteristics of simple and feasible preparation process, high safety and efficacy and significant pharmacological and pharmacodynamic effects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation for treating diabetes and a preparation method thereof, belonging to the technical field of medical preparations. Background technique [0002] Diabetes is a disease of glucose metabolism disorder caused by insufficient insulin secretion in the body. Its incidence is increasing in our country. If the disease is not well controlled for a long time, various complications will occur, such as coronary heart disease, arterial Sclerosis, diabetic nephropathy, etc., can be life-threatening in severe cases. At present, the treatment of diabetes is still based on diet, but it is not enough to alleviate the condition. Common western medicines that can be used include insulin injection and oral hypoglycemic drugs such as Jiatangning, Jiangtangling, glibenclamide, and chlorpropamide, which can only temporarily improve the pathological symptoms, but cannot completely cure them. Side effects, main...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61K9/20A61P3/10
Inventor 赵步长卢露谢伟
Owner 陕西步长高新制药有限公司
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