Ethacridine lactate ointment as well as preparation method and application thereof

A technology of lactic acid ethacridine and ointment, which is applied in the directions of ointment delivery, pharmaceutical formulation, emulsion delivery, etc., can solve the problems of long drug effect cycle, complicated preparation process, insufficient curative effect, etc., and achieves simple composition and preparation. Simple process and the effect of promoting rapid healing

Active Publication Date: 2012-07-11
BEIJING RECTUM HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The above-mentioned ointments, for dressing wound healing after hemorrhoid fistula surgery, have insufficient curative effect pertinence, and some have complex preparation process and long drug effect cycle. After changing the dressing to cure

Method used

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  • Ethacridine lactate ointment as well as preparation method and application thereof
  • Ethacridine lactate ointment as well as preparation method and application thereof
  • Ethacridine lactate ointment as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] 1. Prescription: Ethacridine lactic acid 8g, add white petrolatum to 1000g, and make 1000g ointment.

[0028] 2. Preparation method: Sieve the coarse powder raw material of ethacridine lactic acid for later use; melt vaseline at 50°C, and add it to the above-mentioned pulverized fine powder in proportion. Stir, mix until semi-solidified, that is.

Embodiment 2

[0030] 1. Prescription: Ethacridine lactic acid 9g, add yellow petrolatum to 1000g, and make 1000g ointment.

[0031] 2. Preparation method: Sieve the coarse powder raw material of ethacridine lactic acid for later use; melt yellow petrolatum at 50°C, add it to the above-mentioned pulverized fine powder in proportion, and adjust the speed of the mixer at 160 to carry out in the molten state. Stir at a constant speed and mix until it is semi-solidified.

Embodiment 3

[0033] 1. Prescription: ethacridine lactic acid 10g, add white petrolatum to 1000g, and make 1000g ointment.

[0034] 2. Preparation method: Sieve the coarse powder raw material of ethacridine lactic acid for later use; melt white petrolatum at 55°C, add it to the above-mentioned pulverized fine powder in proportion, and adjust the speed of the mixer at 175 to carry out in the molten state. Stir at a constant speed and mix until it is semi-solidified. The ointment effect that makes by present embodiment is the best.

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Abstract

The invention relates to ethacridine lactate ointment as well as a preparation method and application thereof. The ointment comprises ethacridine lactate which accounts for 0.8-1.2% of the total weight of the ointment. The ointment has the effects of sloughing, generating muscle, sterilizing and disinfecting, and has remarkable curative effects for treating the red and swollen periphery of an anus and healing the wound surface of the anus subjected to anal fistula operation. As a whole, the ethacridine lactate ointment has the advantages of definite curative effect, convenience in use, fast onset of action, safety, aponia and the like; and the effectiveness is up to 100 percent.

Description

technical field [0001] The invention relates to a compound ointment, in particular to an ethacridine lactic acid ointment, its preparation method and application. Background technique [0002] Hemorrhoids and anal fistula are common and frequently-occurring diseases of the anus and rectum. When hemorrhoids are severe or have complications, surgical treatment is required. Due to the special environment of the anus, most of the sores left after hemorrhoids and fistula surgery are open wounds. The healing process It is secondary healing, that is, the wound is filled with granulation tissue first, and then new epithelium covers the wound. In the process of wound repair, the formation of granulation tissue has an important function. It can not only fill the defect of the wound, but also protect the wound surface, prevent bacterial infection, and reduce bleeding. Generally, during 72-144 hours after operation, the granulation tissue grows faster, but the new granulation texture i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K31/473A61P17/02
Inventor 白蕊卢克捷谭静范朱钢何金哲孙冰
Owner BEIJING RECTUM HOSPITAL
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