Pharmaceutical composition for treating hypertension

Abstract

The invention discloses a pharmaceutical composition. The pharmaceutical composition comprises Levoamlodipine or a pharmaceutically-acceptable salt and dogbane leaf extracts. The pharmaceutical composition has a good therapeutic effect on hypertension and has less adverse effects.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a composition composed of levamlodipine or a pharmaceutically acceptable salt thereof and apocynum leaf extract, and the application of the composition in the preparation of drugs for treating hypertension. technical background [0002] Hypertension is a common chronic disease of the cardiovascular system. At present, there is no effective cure in the world. Once the disease occurs, it needs to be taken for life, which seriously endangers human health. In 2009, Professor Liu Lisheng, chairman of the World Hypertension Federation, pointed out: "19% of adults in my country suffer from hypertension, and the number of patients reaches 220 million. At the same time, there are still 10 million new patients every year." Hypertension can cause damage to the heart, brain, kidney and other organs, and is closely related to sugar and lipid metabolism disorders and diabetes, which can significantly r...

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Problems solved by technology

In the national anti-aging drug seminar held by the Chinese Pharmaceutical Association in the 1980s, academic exchanges were carried out on the research of Apocynum leaf. Clinical trial studies and documentation certificates of the Society, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Northwest Institute of Botany, Chinese Academy of Sciences, Institute of Materia Medica, Chinese Academy of Medical Sciences, and other units and pharmaceutical-related units in Shaanxi, Beijing, Shanghai, Nanjing, etc. Apocynum leaves contain a large amount of flavonoids, triterpenes, organic acids, amino acids and other chemical components. Further research on the chemical structure of flavonoids is quercetin and isoquercetin glycosides. Its pharmacological effects include lowering blood pressure, lowering blood fat, and increasing coronary artery flow. It has good curative effect on high blood pressure and high blood fat, especially on dizziness symptoms and improving sleep quality. At the same time, it can enhance immunity, prevent colds, relieve asthma and relieve cough, eliminate depression, promote blood circulation and beautify skin, relieve alcohol and protect liver, and degrade smoke Toxins, softening blood vessels, defecation and diuresis, etc., but have side effects of bradycardia in the heart

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