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Drug conveying device

A delivery device and drug technology, applied in the field of medical devices, can solve the problems of inability to achieve directional drug delivery in diseased blood vessels, large side effects in normal blood vessels, and restenosis of blood vessels, and achieve the effects of repairing vascular endothelial damage, inhibiting cell proliferation, and avoiding coagulation

Active Publication Date: 2012-07-11
SHANGHAI VASOLUTIONS MEDTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the process of realizing the present application, the inventors found that there are at least the following problems in the prior art: whether it is a balloon dilatation operation or a stent placement operation, some complications may be brought about, such as inflammation, vascular intima tear, Hyperplasia of vascular endothelial cells, etc., which may lead to vascular restenosis
However, delivery of certain anti-inflammatory and anti-cell proliferation drugs to diseased blood vessels by oral administration or injection has a certain effect on inhibiting vascular restenosis, but it cannot achieve directional drug delivery to diseased blood vessels, and has a greater effect on normal blood vessels. side effects

Method used

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Experimental program
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Effect test

Embodiment 1

[0025] figure 1 This is a schematic cross-sectional structure diagram of a drug delivery device provided by an embodiment of this application.

[0026] Such as figure 1 As shown, the drug delivery device is a coaxial balloon dilatation catheter, which includes a push rod 1, an inner tube 2, a balloon 3, a visualization marker 4, a stress diffusion tube 5, and a connecting device 6, wherein the push rod 1 is hollow Structure, the distal end is sealed and fixed with the balloon 3, and the proximal end is sealed and fixed with the connecting device 6; the inner tube 2 is also a hollow structure, penetrates the inner cavity of the balloon 3 and the push rod 1, and is connected with the inner cavity of the push rod 1. The cavity is isolated, the distal end passes through the balloon 3 and is sealed and fixed with the balloon 3, and the proximal end is sealed and fixed with the connecting device 6. The connecting device 6 is provided with a guide wire port 8 and an injection port 9, and...

Embodiment 2

[0033] Figure 5 This is a schematic cross-sectional structure diagram of another drug delivery device provided in an embodiment of this application.

[0034] In the embodiment of the present application, the proximal opening of the inner tube of the drug delivery device may not only be arranged at the proximal opening of the push rod, but also may be arranged on the side wall of the push rod.

[0035] Such as Figure 5 As shown, the drug delivery device also includes: a push rod 1, an inner tube 2, a balloon 3, a visualization mark 4, a stress diffusion tube 5, and a connecting device 6, wherein only the injection port 9 is provided on the connecting device 6 and the guide The wire port 8 is arranged at an appropriate position outside the pushing rod 1, and the proximal opening of the inner tube 2 is sealed and fixed with the guide wire port 8. The connection relationship of the other parts of the drug delivery device is the same as in the first embodiment of the present applica...

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PUM

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Abstract

The invention discloses a drug conveying device, comprising a feeding rod, a balloon, an internal tube, a developing mark, a stress diffusion tube and a connection device, wherein a groove is arranged on the surface of the balloon, and a plurality of micropores internally communicated with the interior of the balloon are arranged in the groove. The drug conveying device can be used for directly treating stenosis in a stent or be used for conveying drug to vessels, which are subjected to balloon dilation operation or stent implantation operation. Oriented release of the drug to vascular walls can be realized without the help of any drug coating, so as to repair vascular endothelial injury and restrain hyperplasia of vascular smooth muscle cell. Furthermore, the drug conveying device can be dismounted from a human body after the operation, so as to avoid blood cohesion at vascular pathological change. Therefore, the possibility of vascular restenosis is reduced.

Description

Technical field [0001] This application relates to the technical field of medical devices, in particular to a drug delivery device. Background technique [0002] In recent years, with the aging of our country’s population and the increase in the incidence of diabetes, the prevalence of cardiovascular and peripheral blood vessels has also been rising. In vascular diseases, arterial stenosis will directly endanger the lives of patients. [0003] Interventional surgery has become an important method for the treatment of arterial vascular stenosis due to its advantages of less bleeding, less trauma, less complications, fast postoperative recovery, and safety and reliability. Interventional treatment operations include balloon dilation and stent implantation. Balloon dilatation is the direct delivery of a balloon dilatation catheter to the stenosis of the blood vessel, and the narrowed blood vessel is expanded by the balloon; stent implantation is the expansion of the balloon A stent (...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M29/02A61M31/00
Inventor 赵振心李孝秀郑忠伟谢志永罗七一
Owner SHANGHAI VASOLUTIONS MEDTECH CO LTD
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