New application of carmustine
A technology of carmustine and cocaine, applied in the field of new medical uses of carmustine, can solve the problems of high recurrence risk of patients and the like
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[0019] Embodiment 1, intravenous injection of carmustine 30mg / kg inhibits the relapse induced by low-dose morphine in rats dependent on morphine
[0020] 1. Materials
[0021] Male SD rats (about 65 days old, Experimental Animal Center, Chinese Academy of Military Medical Sciences) weighing about 270-300 grams.
[0022] Drugs: Morphine Hydrochloride Injection (produced by Shenyang No. 1 Pharmaceutical Factory, stock solution concentration is 10 mg / ml, diluted to 1 mg / ml with sterile normal saline when used), carmustine injection (produced by Tianjin Jinyao Amino Acid Co., Ltd., Dilute to 12.5mg / ml with sterile saline when used).
[0023] The self-medication experimental device used in this experiment was purchased from Anlai Software Technology Co., Ltd., with a size of 29cm×29cm×26cm. It is composed of two parts: the box and the control software. The side wall is made of stainless steel plate, and the bottom plate is made of stainless steel fence. The entire box is placed ...
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