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Preparation method of medicinal composition for treating leukorrhea

A composition and leucorrhea technology, applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of slow release of active ingredients of raw materials, affecting the absorption and utilization of active ingredients of drugs, etc., to improve the preparation Quality and production efficiency, reduce dosage, ensure stable effect

Active Publication Date: 2012-07-18
JINHE TIBETAN MEDICINE
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  • Abstract
  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

However, the preparation methods of Liuwei Datuo Yeyunshi powder in the prior art all adopt simple physical treatment of crushing and mixing the raw materials, and the active ingredients of the raw materials are released slowly, which seriously affects the absorption and utilization of the active ingredients of the drug. It is urgent to introduce modern The preparation method provides Liuwei Datuoye Yunshi preparation with fast dissolution, onset of effect and better absorption and utilization

Method used

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  • Preparation method of medicinal composition for treating leukorrhea
  • Preparation method of medicinal composition for treating leukorrhea
  • Preparation method of medicinal composition for treating leukorrhea

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-8

[0027] The proportioning by weight of the crude drug of embodiment 1-8 pharmaceutical composition is as follows:

[0028] Datuo Ye Yunshi 90g, pomegranate seeds 90g, cinnamon 5g, cardamom 40g, longum longum 5g, safflower 50g.

[0029] The commercially available Liuwei Datuo Yeyunshi Powder used as a comparison is a product of Qinghai Jinhe Tibetan Medicine Pharmaceutical Co., Ltd., batch number: 20100820.

Embodiment 1

[0030] Embodiment 1, the preparation of a kind of pharmaceutical composition capsule for the treatment of leucorrhea

[0031] (1) Take cinnamon, cardamom, and longan according to the composition ratio of the raw materials, and add 300 g of water to extract the volatile oil for 5 hours, collect the volatile oil, and filter the medicinal liquid to obtain the extract A' and medicinal liquid. Slag A;

[0032] Add the collected volatile oil into 6% by weight and volume percent β-cyclodextrin aqueous solution, the volume-to-weight ratio of volatile oil to β-cyclodextrin is 1ml: 6g, under stirring condition, keep the temperature at 50°C, stir for 4 hours, 4 Refrigerate at ℃ for 12 hours, filter with suction, and vacuum-dry the precipitate at 50℃ to obtain the clathrate of volatile oil;

[0033] (2) According to the proportioning ratio of the raw materials, take three medicinal materials of Yunshi stiposa, pomegranate and safflower, mix them with the dregs A after extracting the vola...

Embodiment 2

[0035] Embodiment 2, a kind of preparation that is used for the treatment of the pharmaceutical composition tablet of leucorrhea

[0036] (1) Take cinnamon, cardamom, and longan according to the composition ratio of raw materials, add 400 g of water, extract the volatile oil for 4 hours, collect the volatile oil, and filter the medicinal liquid to obtain the extract A' and medicinal liquid. Slag A;

[0037] Add the collected volatile oil into 5% by weight volume percent β-cyclodextrin aqueous solution, the volume-to-weight ratio of volatile oil to β-cyclodextrin is 1ml: 5g, under stirring condition, keep the temperature at 60°C, stir for 4 hours, 4 Refrigerate at ℃ for 24 hours, filter with suction, and vacuum-dry the precipitate at 60℃ to obtain the clathrate of volatile oil;

[0038] (2) According to the proportioning ratio of raw material medicines, take 3 kinds of medicinal materials of Yunshi stipatus, pomegranate seeds and safflower, mix them with the dregs A after extrac...

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Abstract

The invention relates to a preparation method of a medicinal composition for treating leukorrhea. The method comprises the following steps of: extracting volatile oil, and including; extracting with ethanol; molding a preparation, and the like. A volatile oil extraction and inclusion technology is adopted, so that the stability of volatile oil is enhanced; and an extracting technology is adopted, so that invalid impurities are removed, the taking amount is reduced, and the curative effect is enhanced. Different dosage forms are prepared with a modern preparation technology, so that the requirements of different patients are met, and the administration adaptability of patients is improved.

Description

technical field [0001] The invention relates to a preparation method of a pharmaceutical composition, in particular to a preparation method of a pharmaceutical composition for treating leucorrhea. Background technique [0002] Leucorrhea, also known as leucorrhea, is a common and frequently-occurring disease among women. Leucorrhea refers to a significant increase in the amount of leucorrhea, abnormal color, quality, and smell, or accompanied by systemic or local symptoms. There are many causes of leucorrhea, such as trichomonal vaginitis, fungal vaginitis, senile vaginitis, cervical erosion, cervical polyps, endometritis, and cervical cancer. Clinical manifestations are common leucorrhea increased, continuous, low back pain, mental fatigue, etc., or see both red and white, or mixed, or pus with foul smell. The etiology and pathogenesis of this disease are mainly due to the dysfunction of viscera and internal organs, and dampness is generated from the inside; or the lower ...

Claims

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Application Information

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IPC IPC(8): A61K36/9064A61P15/00
Inventor 邵成雷王振江玉娟杨敬燕宋洋
Owner JINHE TIBETAN MEDICINE
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