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Salvia miltiorrhiza and red flower dropping pill and preparation method thereof

A technology of red dripping pills and dripping pills, applied in the field of Danhong dripping pills and its preparation, can solve the problems of incomplete dissolution of active ingredients and inconvenient taking

Inactive Publication Date: 2012-07-25
张睿
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] At present, there are many pharmaceutical preparations with salvia miltiorrhiza and safflower extracts as active ingredients, including injection preparations, oral preparations, etc. But as functional foods, only Danshen safflower tea and Danshen safflower wine are reported, and they are all in the form of slices or coarse powder Form application. It is also inevitable that the active ingredients cannot be completely dissolved and it is inconvenient to take. Therefore, it is necessary to improve.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0071] Prescription of medicinal materials: Danshen slices 2000g, safflower 1000g.

[0072] Extract preparation:

[0073] Take the Danshen medicinal material, crush it into a coarse powder, heat and decoct it with an aqueous solution containing 0.1% sodium bisulfite to extract 4 times, each time for 70 minutes, combine the extracts and centrifuge at 8000 rpm, and adjust the pH value of the centrifuged solution with acid solution To 3, refrigerate, filter, add the filtrate to the AB-8 macroporous absorbent resin column that has been processed, first wash away impurities with water 3 times the volume of the resin column, and then elute with 5 times the volume of 30% ethanol, Collect the ethanol eluate, recover the solvent under reduced pressure until the ratio of the amount of the medicinal solution to the crude drug is 1:2, add n-butanol saturated with water 4 times, combine the extracts, recover the solvent under reduced pressure until dry, and obtain the Danshen extract;

[...

Embodiment 2

[0080] Prescription of medicinal materials: Danshen slices 3000g, safflower 1000g.

[0081] Extract preparation:

[0082] Take the Danshen medicinal material, crush it into a coarse powder, heat and decoct it with an aqueous solution containing 0.1% sodium metabisulfite to extract 3 times, each time for 90 minutes, combine the extracts and centrifuge at 10,000 rpm, and adjust the pH value of the centrifuged liquid to 2 with acid solution , refrigerated, filtered, and the filtrate was added to the treated AB-8 macroporous resin column, first washed with water 3 times the volume of the resin column to remove impurities, then eluted with 3 times the volume of 40% ethanol, and collected ethanol eluate, recover the solvent under reduced pressure until the ratio of medicinal liquid to crude drug is 1:1, extract 3 times with n-butanol saturated with water, combine the extracts, return the solvent to dryness under reduced pressure, and obtain the Danshen extract;

[0083] Take safflo...

Embodiment 3

[0089] Prescription of medicinal materials: Danshen slices 3000g, safflower 1200g.

[0090] Extract preparation:

[0091] Take the Danshen medicinal material, crush it into coarse powder, heat and decoct it with an aqueous solution containing 0.2% sodium bisulfite to extract it 4 times, each time for 70 minutes, and centrifuge the combined extract at a high speed of 12000 rpm, and adjust the pH value of the centrifuged solution with acid solution To 4, refrigerate, filter, add the filtrate to the treated macroporous resin column, first wash with 5 times the volume of the resin column to remove impurities, then elute with 3 times the volume of 50% ethanol, collect the ethanol and wash Remove the liquid, recover the solvent under reduced pressure until the ratio of the medicinal liquid to the crude drug is 1:1, extract 5 times with ethyl acetate, combine the extracts, return the solvent to dryness under reduced pressure, and obtain the Danshen extract;

[0092] Take safflower, ...

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Abstract

The invention belongs to the technical field of health care food and discloses a salvia miltiorrhiza and red flower dropping pill and a preparation method thereof. The salvia miltiorrhiza and red flower dropping pill is characterized in that the dropping pill consists of active ingredients of extracts obtained through extracting salvia miltiorrhiza and red flower according to a weight part ratio being 3:(1-1.5), and the weight part ratio of dripping pill active ingredients to substrates is 1:(3-5). Tests prove that the dropping pill provided by the invention has a good health care effect and is superior to the similar products.

Description

technical field [0001] The invention relates to the technical field of functional food, in particular to a Danhong dripping pill and a preparation method thereof. Background technique [0002] Salvia miltiorrhiza is also known as red ginseng, purple salvia miltiorrhiza, red root and so on. For dicotyledons Lamiaceae, dry roots and rhizomes. Salvia miltiorrhiza was first recorded in "Shen Nong's Materia Medica", listed as top grade. Later generations of herbal medicines have been recorded. The root of Danshen mainly contains fat-soluble diterpenoids and water-soluble phenolic acids, and also contains flavonoids, triterpenoids, sterols and other components. Modern pharmacological research results show that Danshen has relatively Good medicinal effects: In terms of cardiovascular system, it has a strong heart effect, strengthens myocardial contractility, improves heart function, and does not increase myocardial oxygen consumption; in terms of blood vessel effects, it can expa...

Claims

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Application Information

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IPC IPC(8): A23L1/29A23L33/00
Inventor 张睿
Owner 张睿
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