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Medicine composition for treating chronic aplastic anemia and preparation method thereof

A kind of aplastic and compositional technology, applied in the field of medicine, can solve the problems of unsatisfactory curative effect, not much, etc.

Active Publication Date: 2012-08-29
石家庄平安医院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are not many Chinese patent medicines for the treatment of kidney-yang deficiency in aplastic anemia in the domestic market, and the curative effect is not satisfactory

Method used

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  • Medicine composition for treating chronic aplastic anemia and preparation method thereof
  • Medicine composition for treating chronic aplastic anemia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] A pharmaceutical composition for treating chronic aplastic anemia. The main medicinal materials of the pharmaceutical composition are: Hailong 150; Epimedium 100; Radix Pseudostellariae 300; ; Fried malt 200. Its preparation steps include:

[0043] A. Weigh each medicinal raw material according to the above formula, wherein the three flavors of sea dragon, heterophylla, and fried malt are pulverized into coarse powder, and set aside;

[0044] B. The three flavors of Caulis Spatholobus, Rehmannia glutinosa, and Epimedium plus 12 times the amount of water are decocted twice, each time for 1.5 hours, the decoctions are combined, filtered, and the filtrate is concentrated to a relative density of 1.15g / ml-1.25g / ml ( 50~60℃) clear paste;

[0045] C. Add the coarse powder obtained in step A to the clear paste in step B, mix well, and dry at 80°C to obtain final product;

[0046] D, every 100g of the product obtained in step C adds drinking water to 45g~50g honey water to m...

Embodiment 2

[0048] A pharmaceutical composition for treating chronic aplastic anemia. The main medicinal materials of the pharmaceutical composition are: Hailong 140; Epimedium 95; Pseudostellaria 310; Rehmannia glutinosa 210; ; Fried malt 200. Its preparation steps include:

[0049] A, take by weighing each effective raw material according to above-mentioned formula, pulverize into fine powder, sieve;

[0050] B. For every 100g of the obtained powder, add 27g to 33g of refined honey and add water to make 1000g of honeyed pills, and dry to obtain the finished product.

[0051] In addition, honey or other pharmaceutically acceptable excipients can be added to the dry paste, thick paste or powder mixture prepared in the above embodiments of the present invention to make pills or other clinically acceptable granules, dropping pills, tablets, Capsules, suspensions, oral liquid preparations, etc.

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Abstract

The invention discloses a medicine composition for treating chronic aplastic anemia. The medicine composition is prepared by the following main pharmacophore raw materials in parts by weight: 100-200 of thalattosaurus, 50-150 of herba epimedii, 250-400 of radix pseudostellariae, 150-250 of rehmannia, 250-350 of caulis spatholobi, and 150-250 of coloured malt. A preparation method comprises the following steps of: weighing the pharmacophore raw materials according to the formula; and uniformly mixing the pharmacophore raw materials through grinding, water extraction and concentration, or a manner of combining grinding and water extraction and concentration, thereby obtaining the end product. The medicine composition can be used for invigorating the kidney, supplying vital essence and marrow, and hematogenesis, is good for symptoms of various deficiency of essence and blood such as the deficiency of the kidney essence, marrow deficiency and blood disorders, and is used for treating aplastic anemia, myelodysplasia syndrome, leukemia, paroxysmal nocturnal hemoglobinuria, myelofibrosis, and patients with the symptoms caused by chemotherapy and the like.

Description

technical field [0001] The invention relates to the technical field of medicines, in particular to a medicine preparation made from plant Chinese herbal medicines for filling the kidneys, nourishing the essence, benefiting the marrow and generating blood, and a preparation method thereof. Background technique [0002] Chronic aplastic anemia (CAA) is caused by the proliferation and differentiation disorder of bone marrow pluripotent stem cells and the damage of hematopoietic microenvironment caused by physical, chemical, biological factors, drugs and other unknown reasons, as well as immune abnormalities. Decreased total volume, bone marrow hematopoietic failure, and a group of syndromes characterized by pancytopenia. The main clinical manifestations are anemia, bleeding and infection. Aplastic anemia is a common and refractory disease in hematology. With the aggravation of environmental pollution, this disease has an increasing trend. In my country, there are about 25,000 ...

Claims

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Application Information

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IPC IPC(8): A61K36/8998A61P7/00A61P7/06A61K35/56A61K35/60
Inventor 黄怀鹏刘清池李建英陶君李静涵
Owner 石家庄平安医院有限公司
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