Application of integripetal rhodiola herb and ginkgo leaf composition to preparation of anti-hypoxia medicament or health-care food

A technology of health food, rhodiola rosea, which is applied in the application field of medicine or health food, which can solve the problems of reduced ability, achieve the effect of improving deformation ability, preventing and treating cerebral hemorrhage and cerebral infarction, and increasing oxygen carrying capacity

Inactive Publication Date: 2012-09-19
HARBIN ZHENBAO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] 2. Hemorrhagic hypoxia (obstacles in carrying oxygen or releasing oxygen in the blood): due t

Method used

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  • Application of integripetal rhodiola herb and ginkgo leaf composition to preparation of anti-hypoxia medicament or health-care food

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0039] Example 1: Tablets of Rhodiola rosea extract and Ginkgo biloba extract (2.25:1)

[0040] 1. Raw materials: 112.5g of rhodiola extract, 50g of ginkgo biloba extract, 235.5g of microcrystalline cellulose, 48g of 20% starch slurry, 2g of magnesium stearate.

[0041] 2. Preparation method: Weigh the crushed Rhodiola extract, Ginkgo biloba extract, and microcrystalline cellulose that have been crushed through an 80-mesh sieve, mix for 30 minutes, add starch slurry, stir for 20 minutes, and granulate with an 18-mesh nylon sieve, 55℃ Dry for 30 minutes, check that the moisture content is 4.0%, size the granules on an 18-mesh nylon sieve, add magnesium stearate, mix for 20 minutes, and press tablets (0.4g / tablet) to obtain.

[0042] 3. Tablet testing: Check the tablet disintegration time according to the 2010 edition of the Chinese Pharmacopoeia, Appendix XII A, the disintegration time limit inspection method, and check the tablet fragility according to the 2010 edition of the Chinese...

Example Embodiment

[0044] Example 2: Tablets of Rhodiola rosea extract and Ginkgo biloba extract (2:1)

[0045] 1. Raw materials: 170 g of rhodiola extract, 85 g of ginkgo biloba extract, 110 g of microcrystalline cellulose, 210 g of starch, 40 g of hydroxymethyl starch, 85 g of 25% starch slurry, and 4 g of magnesium stearate.

[0046] 2. Preparation method:

[0047] Weigh the crushed Rhodiola extract, Ginkgo biloba extract, microcrystalline cellulose, starch, and hydroxymethyl starch, which have been crushed through an 80-mesh sieve, mix for 20 minutes, add 25% starch slurry, stir for 10 minutes, and pass through an 18-mesh sieve The granules were dried at 60°C for 40 minutes, the moisture content was determined to be 4.3%, and the granules were sieved through an 18-mesh sieve. Magnesium stearate was added, mixed for 30 minutes, and compressed (0.4g / tablet) to obtain.

[0048] 3. Detection: Refer to Example 1 for the detection method, and the result:

[0049] The obtained tablet has a smooth surface, s...

Example Embodiment

[0050] Example 3: Tablets of Rhodiola rosea extract and Ginkgo biloba extract (3:1)

[0051] 1. Raw materials: Rhodiola extract 360g, Ginkgo biloba extract 120g, Microcrystalline cellulose 485g, starch 200g, 15% starch slurry 155g, Magnesium stearate 6g

[0052] 2. Preparation method:

[0053] Weigh the Rhodiola extract, Ginkgo biloba extract, microcrystalline cellulose and starch that have been crushed through an 80-mesh sieve, mix for 40 minutes, add 15% starch slurry, stir for 15 minutes, pass through an 18-mesh sieve, and granulate at 50°C Dry for 60 minutes, detect the moisture content at 3.8%, pass through an 18-mesh sieve, and then add magnesium stearate, mix for 40 minutes, and press tablets (0.4g / tablet) to obtain.

[0054] 3. Detection: The detection method is the same as in Example 1. The result is:

[0055] The obtained tablet has a smooth surface, strong compressibility, good hardness, a disintegration time of 18 minutes, and a friability of 0.106%.

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Abstract

The invention relates to application of an integripetal rhodiola herb and ginkgo leaf composition to the preparation of anti-hypoxia medicaments or health-care food. The composition consists of an integripetal rhodiola herb extract and a ginkgo leaf extract in a weight ratio of (2-10):1. By adopting the ratio, the integripetal rhodiola herb and ginkgo leaf composition is superior to the prior art in an anti-hypoxia aspect.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to the application of rhodiola rosea and ginkgo biloba composition in the preparation of hypoxia-resistant medicine or health food. Background technique [0002] Hypoxia is a pathological process shared by many clinical diseases, and it is an important cause of death caused by many diseases. Oxygen in the atmosphere enters the alveoli through breathing, diffuses into the blood, combines with hemoglobin, is transported by the blood circulation to the whole body, and is finally taken up and utilized by tissues and cells. An obstacle in any of these links can cause hypoxia. When tissues and cells do not receive sufficient oxygen or cannot make full use of oxygen, the pathological process of abnormal changes in the metabolism, function and morphological structure of tissues and cells is called hypoxia. [0003] Hypoxia can be divided into four types: hypoxic hypox...

Claims

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Application Information

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IPC IPC(8): A61K36/41A61P9/00A61P9/10A61P25/00
Inventor 方同华张韬韩磊倪蓓
Owner HARBIN ZHENBAO PHARMA
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