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Sodium bicarbonate injection and preparation method thereof

A sodium bicarbonate, injection technology, applied in blood diseases, pharmaceutical formulations, extracellular fluid diseases, etc., can solve the problem of no sodium bicarbonate injection, etc.

Inactive Publication Date: 2012-10-10
FUJIAN TIANQUAN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] The present invention is proposed for the problem of no clinically usable sodium bicarbonate injection in the prior art, for this reason, the main purpose of the present invention is to provide a kind of sodium bicarbonate injection and preparation method, to solve the above problems

Method used

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  • Sodium bicarbonate injection and preparation method thereof
  • Sodium bicarbonate injection and preparation method thereof
  • Sodium bicarbonate injection and preparation method thereof

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Embodiment Construction

[0014] A kind of sodium bicarbonate injection of the present invention and preparation method are further described below in conjunction with accompanying drawing and specific embodiment.

[0015] The sodium bicarbonate injection prescription provided in the present embodiment is as follows:

[0016] Sodium bicarbonate 46.0~53.5g

[0017] Edetate Calcium Sodium 0.98~0.11g

[0018] Add water for injection to 1000ml

[0019] In the present embodiment, the preferred sodium bicarbonate injection specification is: 250ml: 12.5g.

[0020] Sodium bicarbonate is easily soluble in water. And the prescription among the present embodiment is tested, sodium bicarbonate: 46.0~53.5g, calcium sodium edetate: 0.98~0.11g, water for injection is added to 1000ml. Dissolution is good. After sterilization and storage for more than half a year, it is still colorless and clear.

[0021] Amount of excipients

[0022] Since the sodium bicarbonate raw material contains a small amount of Ca2+, Mg2...

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Abstract

The invention discloses sodium bicarbonate injection and a preparation method thereof. The sodium bicarbonate injection is characterized by comprising 46.0 to 53.5 grams of sodium bicarbonate, 0.98 to 0.11 gram of calcium disodium edentate and 1,000 milliliters of water for injection. By the sodium bicarbonate injection and the preparation method thereof, the problem that the related patent protection of the sodium bicarbonate injection is not provided at present is solved.

Description

technical field [0001] The invention relates to the field of medicine preparation, in particular to a sodium bicarbonate injection and a preparation method thereof. Background technique [0002] Sodium bicarbonate injection can treat metabolic acidosis. It can increase the concentration of carbonate in plasma and neutralize hydrogen ions, thereby correcting acidosis. Sodium bicarbonate injection can alkalize urine. Due to the concentration of carbonate in urine After the increase, the pH value rises, making it difficult for uric acid, sulfa drugs, and hemoglobin to form crystals or aggregate in urine. Sodium bicarbonate injection can suppress acid, and oral administration can quickly neutralize or buffer gastric acid without directly affecting gastric acid secretion. Therefore, the pH in the stomach rises rapidly to relieve the symptoms caused by high gastric acid. Sodium bicarbonate injection is recorded in the 2005 edition of the Chinese Pharmacopoeia. According to the cur...

Claims

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Application Information

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IPC IPC(8): A61K33/00A61K9/08A61P7/08A61K31/198
Inventor 邓志明邓志平邓志清秦怀国
Owner FUJIAN TIANQUAN PHARMA
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