Nicosulfuron soluble granule and preparation method thereof

A nicosulfuron-methyl and soluble technology is applied in the field of nicosulfuron-methyl soluble granules and the preparation thereof, which can solve the problems of reducing the exertion of drug efficacy, low content of active ingredients, affecting disintegration and suspension rate, etc. Packaging and transportation costs and storage space, improving the content of active ingredients, and facilitating the effect of drug efficacy

Active Publication Date: 2012-10-17
QINGDAO HANSEN BIOLOGIC SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This dosage form has problems such as low content of active ingredients, large dosage, high transportation cost, and a large amount of organic solvents, making the formulation cost relatively high.
Although wettable powder and water-dispersible granules can solve the above problems, due to the relatively backward processing equipment and uneven research and development levels, it is difficult to meet the technical requirements for the crushing fineness and granulation process, which affects the disintegration and suspension rate. and other indicators, reducing the efficacy of the product during use

Method used

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  • Nicosulfuron soluble granule and preparation method thereof
  • Nicosulfuron soluble granule and preparation method thereof
  • Nicosulfuron soluble granule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Components and weight: 31.6kg of nicosulfuron technical substance with a purity of 95%, 5kg of alkaline compound sodium carbonate, wetting and dispersing agent calcium lignosulfonate and sodium lauryl sulfate, 5kg and 1.5kg respectively, Penetrant fatty alcohol polyoxyethylene ether 10kg, filler sodium sulfate 46.9kg.

[0041] Absolute ethanol: 5kg.

Embodiment 2

[0043] Components and weight: 42.1kg of nicosulfuron technical substance with a purity of 95%, basic compound sodium carbonate and sodium bicarbonate, 5kg and 2kg respectively, wetting and dispersing agent methylnaphthalenesulfonic acid formaldehyde condensate sulfate and Sodium dodecylbenzene sulfonate, 8kg and 2kg respectively, penetrant dioctyl sulfosuccinate sodium salt 8kg, filler urea 34.9kg.

[0044] Absolute ethanol: 6kg.

Embodiment 3

[0046] Components and weight: 52.7kg of nicosulfuron technical substance with a purity of 95%, basic compound sodium bicarbonate and sodium hydroxide, 8kg and 2kg respectively, wetting and dispersing agent sodium methylene naphthalenesulfonate dibutyl The naphthalene sulfonic acid formaldehyde condensate and the pull-off powder are 6kg and 1.5kg respectively, the penetrant laurocaprazine is 3kg, and the filler sodium chloride is 26.8kg.

[0047] Absolute ethanol: 10kg.

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Abstract

The invention relates to a nicosulfuron soluble granule and a preparation method of the nicosulfuron soluble granule. The nicosulfuron soluble granule is prepared from the following components in percentage by weight: 1%-70% of nicosulfuron, 0.5%-30% of alkali compound, and the balance of agricultural preparation auxiliary elements. The preparation method for the nicosulfuron soluble granule comprises the steps of preparing the raw materials; uniformly mixing ethanol with penetrating agent for later use; crushing and mixing the raw materials; squeezing, pelleting, drying and sieving the raw materials. Due to the nicosulfuron soluble granule, the difficulty that a soluble granule is difficult to prepare as the nicosulfuron is difficult to solve in water is overcome. Compared with a dispersible oil suspension, the content of active ingredients is increased; the dosage in a unit area is reduced; a large quantity of packaging materials, transportation cost and storage space can be saved, no organic solvent is used; and the production cost is greatly lowered. Moreover, the prepared soluble granule has good water solubility, and is beneficial to bringing pesticide effects into play.

Description

technical field [0001] The invention belongs to the technical field of agricultural herbicides, and in particular relates to a nicosulfuron-methyl soluble granule and a preparation method thereof. Background technique [0002] Nicosulfuron (nicosulfuron), also known as Yu Nongle; its chemical name is 2-(4,6-dimethoxypyrimidin-2-ylcarbamoylaminosulfonyl)-N,N-dimethyl Niacinamide. Nicosulfuron is a systemic herbicide, which can be absorbed by the stems, leaves and roots of weeds, and then conducts in the plants, causing growth stagnation, chlorosis of stems and leaves, and gradual death of sensitive plants. Generally, they die within 20-25 days. But it takes longer for some perennial weeds in lower temperatures. The efficacy of pesticide application is good before the 4-leaf stage after budding, and the efficacy of pesticide application decreases when the seedlings are large. The drug has pre-emergence herbicidal activity, but the activity is lower than that of post-emergen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N47/36A01N25/14A01P13/00
Inventor 张黎辉薛泽程郝丽霞陶琳
Owner QINGDAO HANSEN BIOLOGIC SCI
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